4-[(E)-({4-[Bis­(2-hy­droxy­eth­yl)amino]­phen­yl}imino)­meth­yl]phenol

In the title compound, C17H20N2O3, the amino N atom is in a planar environment (sum of angles = 360.0°). All hy­droxy H atoms are involved in hydrogen bonding. In the crystal structure, two O—H⋯O and an O—H⋯Nimino hydrogen bond result in the formation of a three-dimensional network. The latter hydrogen bonding causes distortion of the planarity of the 4-HO–C6H4–CH=N–C6H4– fragment by rotation around the =N—CPh bond. The crystal studied was a non-merohedral twin [refined BASF parameter for the major component = 0.5293 (7)]

2,2′-(4-{[(E)-4-Meth­oxy­benzyl­idene]amino}­phenyl­imino)­diethanol

In the title compound, C18H22N2O3, the dihedral angle between the aromatic rings is 3.9 (2)°. Both H atoms of the hy­droxy groups are involved in inter­molecular O—H⋯O hydrogen bonding. In the crystal structure, this hydrogen bonding assembles mol­ecules into chains of 21 symmetry extending parallel to the b axis. The almost planar (within 0.09 and 0.06 Å) 4-CH3O–C6H4–CH=N–C6H4– groups are oriented outwards the twofold screw axis

Evaluation of portable colposcopy and human papillomavirus testing for screening of cervical cancer in rural China

OBJECTIVE: To evaluate the use of a portable, rechargeable colposcope combined with human papillomavirus (HPV) testing, as compared with HPV testing alone, for screening of cervical cancer and pre-cancerous lesions. METHODS: This was a cross-sectional study among 488 women in Baoshan County, Yunnan. The women underwent HPV testing followed by Gynocular portable colposcopy with visual inspection with acetic acid. Obvious lesions were biopsied. If portable colposcopy testing was negative but HPV testing was positive, the women underwent follow-up testing with thin-prep cytology and traditional colposcopy. Cervical biopsies were performed for any abnormalities. Histopathology was followed up with diagnosis and treatment. RESULTS: Among 488 women screened with portable colposcopy, 24 women underwent biopsy based on positive colposcopy screening. Of these 24 women, three were HPV positive and 21 were HPV negative. Five women had cervical intra-epithelial neoplasia (CIN) I and one had advanced cervical cancer. Forty-six women tested positive for HPV. Three of these women had screened positive on preliminary colposcopy, with one positive for CIN III/squamous cell carcinoma and one woman with CIN I. Forty-three women underwent follow-up testing with thin-prep cytology. Two women had atypical squamous cells of undetermined significance and five had low-grade squamous intra-epithelial lesions and were biopsied; three women had CIN I, one had CIN II and one had CIN III. HPV testing and portable colposcopy was more sensitive but slightly less specific than portable colposcopy or HPV testing alone. CONCLUSION: While HPV testing has high sensitivity and specificity for the detection of pre-cancerous and cancerous lesions and portable colposcopy has lower specificity, both methods of detection have low positive predictive value and high negative predictive value. In tandem, HPV testing and portable colposcopy had higher sensitivity for detection among women who underwent biopsies. In clinical practice, portable colposcopy was an effective, easy and affordable tool to transport to villages where cytology is not currently feasible

6-(4-Methyl­phen­yl)-2,10-dioxo-3,9-dioxa-6-aza-1(1,1′)-ferrocenacyclo­deca­phane

In the title compound, [Fe(C23H23NO4)], the two cyclo­penta­dienyl (Cp) rings are nearly parallel, with a dihedral angle of 2.1 (1)°. The distance between the centroids of the Cp rings is 3.277 (8) Å. The relative orientation of the two Cp rings is characterized by a torsion angle of −64.3 (3)° defined by the two centroids and two substituted atoms

4-Methyl-2,7-dioxo-3,6-dioxa-1(1,1′)-ferrocenacyclo­hepta­phane

In the title compound, [Fe(C15H14O4)], the two cyclo­penta­dienyl (Cp) rings are nearly parallel, making a dihedral angle of 2.6 (1)°. The distance between the centroids of the Cp rings is 3.309 (8) Å. The relative orientation of the two Cp rings is characterized by a torsion angle of −43.99 (6)° defined by the two centroids and the two substituted C atoms

Understanding health and social challenges for aging and long-term care in China

The second King’s College London Symposium on Ageing and Long-term Care in China was convened from 4 to 5th July 2019 at King’s College London in London. The aim of the Symposium was to have a better understanding of health and social challenges for aging and long-term care in China. This symposium draws research insights from a wide range of disciplines, including economics, public policy, demography, gerontology, public health and sociology. A total of 20 participants from eight countries, seek to identify the key issues and research priorities in the area of aging and long-term care in China. The results published here are a synthesis of the top four research areas that represent the perspectives from some of the leading researchers in the field. © The Author(s) 2020

Skills' sets and shared benefits: perceptions of resettled people from the Yangtze-Huai River Diversion Project in China

Development induced displacement and resettlement (DIDR) projects should share their benefits with those affected by them. This paper shows that in the case of the Yangtze-Huai River Diversion Project in China perceptions of compensation received differs amongst different groups of resettled people even if levels of compensation are similar. Based on a survey with displaced people, a fuzzy comprehensive evaluation concludes that those with generic skills’ sets are the most satisfied, mainly because they are able to find new work and re-establish livelihoods after resettlement more quickly. On the other hand, those with only agricultural skills find it difficult to re-establish their livelihood and are often dissatisfied. Finally, those who did not have any work before resettlement were found to be satisfied overall as their life quality is said to have improved. The skills of those affected are therefore a key explanatory factor for satisfaction with compensation following resettlement