Problems and Suggestions for Professional Course Teaching of Finance

Finance is one of the most popular majors in higher education, whose professional courses cover the theoretical basis and practical skills related to finance. Learning finance knowledge is the basic path for students to master finance related knowledge and carry out financial work. This paper analyzes the characteristics of finance courses, based on the example of Financial Engineering, identifies the problems in classroom teaching and proposes appropriate countermeasures

Digital photoprogramming of liquid-crystal superstructures featuring intrinsic chiral photoswitches

Dynamic patterning of soft materials in a fully reversible and programmable manner with light enables applications in anti-counterfeiting, displays and labelling technology. However, this is a formidable challenge due to the lack of suitable chiral molecular photoswitches. Here, we report the development of a unique intrinsic chiral photoswitch with broad chirality modulation to achieve digitally controllable, selectable and extractable multiple stable reflection states. An anti-counterfeiting technique, embedded with diverse microstructures, featuring colour-tunability, erasability, reversibility, multi-stability and viewing-angle dependency of pre-recorded patterns, is established with these photoresponsive superstructures. This strategy allows dynamic helical transformation from the molecular and supramolecular to the macroscopic level using light-activated intrinsic chirality, demonstrating the practicality of photoprogramming photonics

Analysis on the evolution process of BFW-like model with explosive percolation of multiple giant components

Recently, the modified BFW model on random graph [Phys. Rev. Lett., 106, 115701 (2011)], which shows a strongly discontinuous percolation transition with multiple giant components, has attracted much attention from physicists, statisticians and materials scientists. In this paper, by establishing the theoretical expression of evolution equations on the modified BFW model, the steady-state and evolution process are analyzed and a close correspondence is built between the values of parameter \alpha and the number of giant components in steady-states, which fits very well with the numerical simulations. In fact, with the value of \alpha decreasing to 0.25, the error between theoretical and numerical results is smaller than 4% and trends to 0 rapidly. Furthermore, the sizes of giant components for different evolution strategies can also be obtained by solving some constraints derived from the evolution equations. The analysis of the steady-state and evolution process is of great help to explain why the percolation of modified BFW model is explosive and how explosive it is.Comment: 12 pages, 5 figure

Quantitative proteomics analysis reveals an important role of the transcriptional regulator UidR in the bacterial biofilm formation of Aeromonas hydrophila

IntroductionBacterial biofilm is a well-known characteristic that plays important roles in diverse physiological functions, whereas the current intrinsic regulatory mechanism of its formation is still largely unknown. MethodsIn the present study, a label-free based quantitative proteomics technology was conducted to compare the differentially expressed proteins (DEPs) between ΔuidR and the wild-type strain in the biofilm state.ResultsThe results showed that the deletion of gene uidR encoding a TetR transcriptional regulator significantly increased the biofilm formation in Aeromonas hydrophila. And there was a total of 220 DEPs, including 120 up-regulated proteins and 100 down-regulated proteins between ΔuidR and the wild-type strain based on the quantitative proteomics. Bioinformatics analysis suggested that uidR may affect bacterial biofilm formation by regulating some related proteins in glyoxylic acid and dicarboxylic acid pathway. The expressions of selected proteins involved in this pathway were further confirmed by q-PCR assay, and the results was in accordance with the quantitative proteomics data. Moreover, the deletion of four genes (AHA_3063, AHA_3062, AHA_4140 and aceB) related to the glyoxylic acid and dicarboxylic acid pathway lead to a significant decrease in the biofilm formation. DiscussionThus, the results indicated that uidR involved in the regulatory of bacterial biofilm formation, and it may provide a potential target for the drug development and a new clue for the prevention of pathogenic A. hydrophila in the future

ATP-dependent dynamic protein aggregation regulates bacterial dormancy depth critical for antibiotic tolerance

Cell dormancy is a widespread mechanism used by bacteria to evade environmental threats including antibiotics. Here we monitored bacterial antibiotic tolerance and regrowth at the single-cell level and found that each individual survival cell shows different ‘dormancy depth’, which in return regulates the lag time for cell resuscitation after removal of antibiotic. We further established that protein aggresome - a collection of endogenous protein aggregates - is an important indicator of bacterial dormancy depth, whose formation is promoted by decreased cellular ATP level. For cells to leave the dormant state and resuscitate, clearance of protein aggresome and recovery of proteostasis are required. We revealed the ability to recruit functional DnaK-ClpB machineries, which facilitate protein disaggregation in an ATP-dependent manner, determines the lag time for bacterial regrowth. Better understanding of the key factors regulating bacterial regrowth after surviving antibiotic attack could lead to new therapeutic strategies for combating bacterial antibiotic tolerance

Electrostatic Self-Assembling Formation of Pd Superlattice Nanowires from Surfactant-Free Ultrathin Pd Nanosheets

A facile method has been developed for face-to-face assembly of two-dimensional surfactant-free Pd nanosheets into one-dimensional Pd superlattice nanowires. The length of the Pd nanowires can be well controlled by introducing cations of different concentration and charge density. Our studies reveal that cations with higher charge density have stronger charge-screening ability, and their introduction leads to more positive zeta-potential and decreased electrostatic repulsion between negatively charged Pd nanosheets. Moreover, their surfactant-free feature is of great importance in assembling the Pd nanosheets into superlattice nanowires. While the cations are important for the assembly of Pd nanosheets, the use of poly(vinylpyrrolidone) is necessary to enhance the stability of the assembled superlattice nanowires. The as-assembled segmented Pd nanowires display tunable surface plasmon resonance features and excellent hydrogen-sensing properties.MOST of China 2011CB932403 2014CB932004 NSFC 21131005 21333008 21420102001 NFFTBS J131002