406 research outputs found
Social Media, Professional Media, and Mobilization in Contemporary Britain:Explaining the Strengths and Weaknesses of the Citizensā Movement 38 Degrees
This article was published in the journal Political Studies [SAGE Ā© The Author(s)] and the definitive version is available at: https://doi.org/10.1177/0032321716631350Digital media continue to reshape political activism in unexpected ways. Within a period of a few years, the internet-enabled UK citizensā movement 38 Degrees has amassed a membership of 3 million and now sits alongside similar entities such as Americaās MoveOn, Australiaās GetUp! and the transnational movement Avaaz. In this article, we contribute to current thinking about digital media and mobilisation by addressing some of the limitations of existing research on these movements and on digital activism more generally. We show how 38 Degreesā digital network repertoires coexist interdependently with its strategy of gaining professional news media coverage. We explain how the oscillations between choreographic leadership and member influence and between digital media horizontalism and elite media-centric work constitute the space of interdependencies in which 38 Degrees acts. These delicately balanced relations can quickly dissolve and be replaced by simpler relations of dependence on professional media. Yet despite its fragility, we theorise about how 38 Degrees may boost individualsā political efficacy, irrespective of the outcome of individual campaigns. Our conceptual framework can be used to guide research on similar movements
Digital Politics: Mobilization, Engagement, and Participation
The article provides insights into the driving forces that underpin new forms of political participation. Digital technologies offer opportunities for engaging in a wide range of civicallyoriented activities, each of which can contribute to deeper democratic engagement. Conventional acts of political participation are argued to be driven primarily by intrinsic motivations relating to self-efficacy and empowerment with participants feeling they can have influence over decision makers. Little research explores whether similar motivations drive participation in less conventional acts, as well as whether mobilisation attempts via social media by peers or political organisations mediate those motivations. Drawing on data from a survey among a representative sample of the UK electorate, we find the offline and online spheres of agency remain fairly distinct. Intrinsic and extrinsic motivations both matter but extrinsic motivations have the strongest explanatory power independent of the sphere of activity. The mediating effect of mobilisation tactics has a minimal effect on extrinsic motivations, online or offline, but online intrinsic motivations lose their explanatory power. As intrinsic factors offer little explanatory power some forms of online political participation may lack meaning to the individual. Rather, these non-conventional acts result from reward seeking and are more likely to be encouraged by non-governmental campaigning organizations suggesting social media users are most likely to perform simple acts in support of non-contentious causes
Developing serious games for cultural heritage: a state-of-the-art review
Although the widespread use of gaming for leisure purposes has been well documented, the use of games to support cultural heritage purposes, such as historical teaching and learning, or for enhancing museum visits, has been less well considered. The state-of-the-art in serious game technology is identical to that of the state-of-the-art in entertainment games technology. As a result, the field of serious heritage games concerns itself with recent advances in computer games, real-time computer graphics, virtual and augmented reality and artificial intelligence. On the other hand, the main strengths of serious gaming applications may be generalised as being in the areas of communication, visual expression of information, collaboration mechanisms, interactivity and entertainment. In this report, we will focus on the state-of-the-art with respect to the theories, methods and technologies used in serious heritage games. We provide an overview of existing literature of relevance to the domain, discuss the strengths and weaknesses of the described methods and point out unsolved problems and challenges. In addition, several case studies illustrating the application of methods and technologies used in cultural heritage are presented
Why People Dual Screen Political Debates and Why It Matters for Democratic Engagement
Dual screening during televised election debates is a new domain in which political elites and journalists seek to influence audience attitudes and behavior. But to what extent do non-elite dual screeners seek to influence others, particularly their social media followers, social media users in general, and even politicians and journalists? And how does this behavior affect short- and longer-term engagement with election campaigns? Using unique, event-based, panel survey data from the main 2015 UK general election debate (Wave 1 = 2,351; Wave 2 = 1,168) we reveal the conditions under which people experience agency, empowerment, and engagement now that social media have reconfigured broadcast political television
Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques
Hepatitis B virus (HBV) is a major global health concern, and the development of curative therapeutics is urgently needed. Such efforts are impeded by the lack of a physiologically relevant, pre-clinical animal model of HBV infection. Here, we report that expression of the HBV entry receptor, human sodium-taurocholate cotransporting polypeptide (hNTCP), on macaque primary hepatocytes facilitates HBV infection in vitro, where all replicative intermediates including covalently closed circular DNA (cccDNA) are present. Furthermore, viral vector-mediated expression of hNTCP on hepatocytes in vivo renders rhesus macaques permissive to HBV infection. These in vivo macaque HBV infections are characterized by longitudinal HBV DNA in serum, and detection of HBV DNA, RNA, and HBV core antigen (HBcAg) in hepatocytes. Together, these results show that expressing hNTCP on macaque hepatocytes renders them susceptible to HBV infection, thereby establishing a physiologically relevant model of HBV infection to study immune clearance and test therapeutic and curative approaches
Adolescent Religiosity and Selective Exposure to Television
Relying on the Adolescent Media Practice Model and selective exposure theory, this study investigated whether religious adolescents watch less mature television entertainment programs than their less religious peers. Program maturity was measured using V-chip ratings, with higher maturity scores indicating content that included more sexuality, violence, and/or adult and sexual language. The responses from 1,335 16- to 18-year-olds who completed Wave 2 of the National Study of Youth and Religion (NSYR) survey were analyzed. Findings indicate that religiosity contributes to explaining the variance in television maturity means, with more religious adolescents indicating a preference for less mature television entertainment. Gender, race, income, and parentsā monitoring of teensā media were also found to influence television maturity. Teensā attitudes toward premarital sex appeared to mediate the effect of religiosity on their television entertainment choices
Geographical imagination and technological connectivity in East Africa
The paper analyses and compares two transformative moments of technologically-mediated change in East Africa, the construction of the Uganda railway between Mombasa and Lake Victoria (1896-1903) and the introduction of fibre-optic cables that landed into the ports of Dar Es Salaam and Mombasa in 2009.
It uses discourse analysis to examine how technologically-mediated connectivity has been represented by political and economic actors during these transformative moments. In both cases, we explore the origins of the expectations of connectivity and the hope and fear associated with them.
Building on Masseyās notion of power-geometry and Sheppardās concept of positionality the paper focuses on power relationships in discussions of connectivity and asks how people understand the abilities of transformative technologies to modify positionalities and alter relational distance and proximity. Ultimately, by examining historical and contemporary expectations of connectivity in East Africa, this paper allows us to work towards creating more grounded and historicised understandings of the coming-together of technology and connectivity
I Click, Therefore I am:Predicting Clicktivist-Like Actions on Candidatesā Facebook Posts During the 2016 US Primary Election
Synergistic Activation of Cardiac Genes by Myocardin and Tbx5
Myocardial differentiation is associated with the activation and expression of an array of cardiac specific genes. However, the transcriptional networks that control cardiac gene expression are not completely understood. Myocardin is a cardiac and smooth muscle-specific expressed transcriptional coactivator of Serum Response Factor (SRF) and is able to potently activate cardiac and smooth muscle gene expression during development. We hypothesize that myocardin discriminates between cardiac and smooth muscle specific genes by associating with distinct co-factors. Here, we show that myocardin directly interacts with Tbx5, a member of the T-box family of transcription factors involved in the Holt-Oram syndrome. Tbx5 synergizes with myocardin to activate expression of the cardiac specific genes atrial natriuretic factor (ANF) and alpha myosin heavy chain (Ī±-MHC), but not that of smooth muscle specific genes SM22 or smooth muscle myosin heavy chain (SM-MHC). We found that this synergistic activation of shared target genes is dependent on the binding sites for Tbx5, T-box factor-Binding Elements (TBEs). Myocardin and Tbx5 physically interact and their interaction domains were mapped to the basic domain and the coil domain of myocardin and Tbx5, respectively. Our analysis demonstrates that the Tbx5G80R mutation, which leads to the Holt-Oram syndrome in humans, failed to synergize with myocardin to activate cardiac gene expression. These data uncover a key role for Tbx5 and myocardin in establishing the transcriptional foundation for cardiac gene activation and suggest that the interaction of myocardin and Tbx5 maybe involved in cardiac development and diseases
Making sense of policy choices: understanding the roles of value predispositions, mass media, and cognitive processing in public attitudes toward nanotechnology
Using a nationally representative telephone survey of 1,015 adults in the United States, this study examines how value predispositions, communication variables, and perceptions of risks and benefits are associated with public support for federal funding of nanotechnology. Our findings show that highly religious individuals were less supportive of funding of nanotech than less religious individuals, whereas individuals who held a high deference for scientific authority were more supportive of funding of the emerging technology than those low in deference. Mass media use and elaborative processing of scientific news were positively associated with public support for funding, whereas factual scientific knowledge had no significant association with policy choices. The findings suggest that thinking about and reflecting upon scientific news promote better understanding of the scientific world and may provide a more sophisticated cognitive structure for the public to form opinions about nanotech than factual scientific knowledge. Finally, heuristic cues including trust in scientists and perceived risks and benefits of nanotech were found to be associated with public support for nanotech funding. We conclude with policy implications that will be useful for policymakers and science communication practitioners
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