8 research outputs found
Why the article that led to the widespread use of hydroxychloroquine in COVID-19 should be retracted.
Commentary: Microbial panaceas: does development have the answer? – reflections on Cowan, Dinan, & Cryan (2020)
Is the microbiome a promising adjunct, a potential panacea, or a distraction from feasible treatments for neurodevelopmental disorders? Taking a developmental approach may get us closer to understanding the data and give us pause in trying to translate this nascent field to the clinic right now
Genetic heterogeneity among Vibrio alginolyticus isolated from shrimp farms by PCR fingerprinting
Molecular epidemiology of Vibrio cholerae and campylobacters isolated in Asian countries
The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway
The incretin hormone glucagon-like peptide 1 (GLP-1) promotes glucose homeostasis and enhances beta-cell function. GLP-1 receptor agonists (GLP-1 RAs) and dipeptidyl peptidase-4 (DPP-4) inhibitors, which inhibit the physiological inactivation of endogenous GLP-1, are used for the treatment of type 2 diabetes. Using the Metabochip, we identified three novel genetic loci with large effects (30-40%) on GLP-1-stimulated insulin secretion during hyperglycemic clamps in nondiabetic Caucasian individuals (TMEM114; CHST3 and CTRB1/2; n = 232; all