Pollution Prevention and Business Management. Curricula for Schools of Business and Public Health. Volume 1: Modules 1-3

These instructional modules are based on the premise that sustained economic development is dependent upon sustained protection ofthe environment. They also reflect the fact that preventing waste is far more cost effective than managing the waste once it is generated. Pollution prevention not only offers businesses a competitive opportunity, it is a natural extension of sound management practices. Incorporating pollution prevention into business management and government regulation will enhance longterm economic prosperity.published or submitted for publicatio

The Canons of Dordt as a Missional Document

Editor\u27s Note: Dr. Lyle Bierma presented this paper at the Prodigal Love of God Conference, sponsored by Dordt University and co-sponsored by the Lilly Fellowship Program as a regional conference, April 2019, at Dordt University, in celebration of the 400th anniversary of the Canons of Dort. In the subsequent articles, Dordt and Dort will be used interchangeably

A Feminist Critique of Human Resource Development Research

This paper shares the results of a critique of human resource development (HRD) research, according to a feminist research framework. The paper offers a brief description of feminist research and challenges HRD researchers to be more critical of their practice

Gewoon artrose

Gewoon artrose. Is artrose inderdaad zo gewoon? Ja, helaas wel. Iedereen weet wel een familielid of bekende op te noemen die geopereerd is voor artrose, en als u in uw omgeving navraagt, blijken er nog veel meer mensen last van te hebben. Artrose, in de volksmond gewrichtslijtage, is een heel gewone aandoening die veel voorkomt, vooral op oudere leeftijd, die niet levensbedreigend is. “Ach, het is de ouderdom, ik moet er maar mee leren leven” zal u niet onbekend in de oren klinken. Gewoon, een hinderlijke aandoening. Maar ondanks dat artrose, èn de last die mensen daarvan hebben, zoveel voorkomt, hebben we op heel veel gewone vragen over artrose nog geen antwoord. Vandaag aanvaard ik mijn benoeming op een bijzondere leerstoel voor deze zeer gewone aandoening, de eerste in Nederland. Ik ga u de komende drie kwartier laten zien waarom deze nieuwe leerstoel noodzakelijk is, èn wat u van mij en mijn team aan inspanningen mag verwachten. Rede, uitgesproken ter gelegenheid van het aanvaarden van het ambt van bijzonder hoogleraar met als leeropdracht Artrose en gerelateerde aandoeningen, aan het Erasmus MC, faculteit van de Erasmus Universiteit Rotterdam op 16 december 201

Every Tribe and Tongue: A Biblical Vision for Language in Society

Every Tribe and Tongue offers a way, first, to rediscover biblical stories and principles that relate to questions about immigration and societal multilingualism, and, second, to outline possible ways to guide thoughtful engagement in the discourse of the public square based on the biblical witness. We will try to show that, far from being an afterthought in the Bible, the call to love our neighbors and to gather people of every nation together in the worship of God is at the very core of the gospel message.Two powerful passions animate this book from beginning to end. First, this work is saturated in a deeply rooted love of the diversity of human languages that are one of God\u27s gracious gifts to human beings. Second, this book is dedicated to calling the North American church to take seriously its charge not simply to love the stranger and alien but to live as strangers and aliens within the American nation to which it has been called to witness to Jesus Christ.https://digitalcommons.cedarville.edu/alum_books/1042/thumbnail.jp

Osteoarthritis subpopulations and implications for clinical trial design

Treatment guidelines for osteoarthritis have stressed the need for research on clinical predictors of response to different treatments. However, identifying such clinical predictors of response is less easy than it seems, and there is not a given classification of osteoarthritis subpopulations. This review article highlights the key methodical issues when analyzing and designing clinical studies to detect important subgroups with respect to treatment effect. In addition, we discuss the main osteoarthritis subpopulations and give examples of how specific treatment effects in these subpopulations have been assessed

Multimodal Machine Learning-based Knee Osteoarthritis Progression Prediction from Plain Radiographs and Clinical Data

Knee osteoarthritis (OA) is the most common musculoskeletal disease without a cure, and current treatment options are limited to symptomatic relief. Prediction of OA progression is a very challenging and timely issue, and it could, if resolved, accelerate the disease modifying drug development and ultimately help to prevent millions of total joint replacement surgeries performed annually. Here, we present a multi-modal machine learning-based OA progression prediction model that utilizes raw radiographic data, clinical examination results and previous medical history of the patient. We validated this approach on an independent test set of 3,918 knee images from 2,129 subjects. Our method yielded area under the ROC curve (AUC) of 0.79 (0.78-0.81) and Average Precision (AP) of 0.68 (0.66-0.70). In contrast, a reference approach, based on logistic regression, yielded AUC of 0.75 (0.74-0.77) and AP of 0.62 (0.60-0.64). The proposed method could significantly improve the subject selection process for OA drug-development trials and help the development of personalized therapeutic plans