Resistance to ceftaroline - 2018 review

Ceftaroline is a new fifth generation cephalosporin, active mostly against Gram-positive cocci, e.g. Staphylococcus aureus (including methicillin-resistant Staphylococcus aureus). It is used in treating acute bacterial skin and skin structure infections, community acquired respiratory tract infections and methicillin-resistant S. aureus bacteremia. The main resistance mechanisms of bacteria to β-lactam antibiotics, including ceftaroline, are mutations in PBP2a, PBP3 and PBP4. Clinically significant resistance has been noted among both archived and newly-isolated strains in a laboratory test using serial passages. Ceftaroline-resistant strains have also been found in patients suffering from cystic fibrosis, ventilator-associated pneumonia and infectious endocarditis. Irresponsible antibiotic treatment using ceftaroline or other antibiotics (due to a possibility of a cross-resistance) can lead to the spread of ceftaroline resistance and, consequently, its loss of value. DOI: http://dx.doi.org/10.5281/zenodo.130443

Physiotherapy in ankylosing spondylitis

Ankylosing spondylitis (AS) is a chronic and progressive systemic disease characterized by the occurrence of inflammation and later ossification in the sacroiliac joints, spine joints, peripheral joints and tendons. It causes pain, swelling, limitation of mobility and partial or complete stiffness of the spine joints. AS is the second most common inflammatory disease of the joints right after rheumatoid arthritis. In most patients, the first symptoms appear between 15 and 40 years of life. In 90% of patients, the presence of HLA-B27 antigen is found. However, not everyone with this antigen will be affected by AS. This disease is 2-3 times more likely to affect men than women

Kalcyfilaksja — śmiertelne powikłanie nie tylko u pacjentów ze schyłkową niewydolnością nerek

We present a fatal case of end-stage renal disease complication that is calciphylaxis, also known as calcific uremic arteriolopathy, characterized by vascular calcification, necrosis of the skin and adipose tissue and constant severe pain of the affected areas.We present a fatal case of end-stage renal disease complication that is calciphylaxis, also known as calcific uremic arteriolopathy, characterized by vascular calcification, necrosis of the skin and adipose tissue and constant severe pain of the affected areas

The role of physical activity in the treatment of type 2 diabetes – editorial article

Balcerska Kamila, Bielejewska Marta, Ciecierska Dominika, Wojtczak Paweł, Gąsior Paulina, Wrzesiński Bartłomiej. The role of physical activity in the treatment of type 2 diabetes – editorial article. Journal of Education, Health and Sport. 2018;8(9):1584-1591 eISNN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1438125 http://ojs.ukw.edu.pl/index.php/johs/article/view/6095 https://pbn.nauka.gov.pl/sedno-webapp/works/879780 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part b item 1223 (26/01/2017). 1223 Journal of Education, Health and Sport eissn 2391-8306 7 © The Authors 2018; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 02.08.2018. Revised: 18.08.2018. Accepted: 15.09.2018. The role of physical activity in the treatment of type 2 diabetes – editorial article Kamila Balcerska, Marta Bielejewska1, Dominika Ciecierska2, Paweł Wojtczak2, Paulina Gąsior1, Bartłomiej Wrzesiński3 1Department and Clinic of Geriatrics, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus in Torun, Poland 2Interdisciplinary Research Club of Geriatrics at the Clinical Geriatry clinic of University Hospital No.1 in Bydgoszcz, Poland 3Scientific Circle at the Department of Ergonomics and Physiology of Physical Effort, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus in Torun, Poland [email protected], ORCID: 0000-0002-5219-720X [email protected], ORCID: 0000-0002-3692-4315 [email protected], ORCID: 0000-0001-9420-9451 [email protected], ORCID: 0000-0003-0683-7007 [email protected], ORCID: 0000-0001-7176-0080 [email protected] ORCID: 0000-0002-4731-5371 Abstract Type 2 diabetes belongs to the group of civilization diseases of the 21st century. In Poland, over 3 million people suffer from diabetes, including 1 million being undiagnosed. In the initial stage, this disease does not hinder functioning in everyday life, often people get to know about being affected by this disease during other diagnostic tests related to another illness. As diabetes develops, there may be numerous complications, including: retinopathy, nephropathy, neuropathy, cerebrovascular disease, ischemic heart disease, peripheral artery disease. Untreated type 2 diabetes can lead to death, so it is very important to start treatment quickly. The aim of therapy is to balance carbohydrate and lipid metabolism, achieve optimal blood pressure, proper body weight, and prevent complications. This can be achieved by combining a properly selected diet, physical activity and pharmacotherapy. [1,2

Physiotherapeutic treatment after break and reconstruction of ACL

Injuries of the knee joint are amongst the most common diseases that affect the human body. It is estimated that they affect about 15-30% of all body injuries. Beside the lateral ligaments the most the structure exposed for the any kind of damage is ACL. Concerning the cruciate ligaments, as much as 90% of the injuries are related to ACL [52]. Most often the damage to this structure occurs when practicing sports, both contact (for example basketball, football, martial arts) and non-contact like skiing

Ostre uszkodzenie nerek i mikroangiopatia zakrzepowa spowodowane nadciśnieniem złośliwym u 21-letniego pacjenta

We present a case of a severe cardiovascular emergency in a 21-year-old patient — malignant hypertension complicated by acute kidney injury and thrombotic microangiopathy.Przedstawiono opis przypadku zagrażającego życiu stanu nagłego u 21-letniego pacjenta, jakim jest nadciśnienie złośliwe powikłane ostrym uszkodzeniem nerek i mikroangiopatią zakrzepową

The use of physiotherapy and the role of physical exercise in cancer

After the application of oncological treatment, it is important to implement physiotherapy, the basic component of which is kinesitherapy. It is not always possible to implement the rehabilitation procedure early enough, so you should take into account the time spent in bed before starting the exercise and assess the physical performance. Research shows that the best benefits are achieved by activity undertaken 5 days a week, lasting a minimum of 30 minutes, with moderate intensity. Physical activity in the advanced stage of cancer can positively affect the physical and mental well-being, the level of fatigue experienced, and even increase the independence of the patient. The aim of using palliative procedures is primarily to control persistent and severe pain, prevent the negative effects of immobilization and provide psychological support for the patient and family members. Numerous studies also indicate that exercise can also help to reduce the risk of certain forms of cancer, and increase the survival time from the moment of diagnosis. Researchers also confirming a favorable correlation between physical effort and the quality of life of patients suffering from cancer

Orientational order parameters of a de Vries–type ferroelectric liquid crystal obtained by polarized Raman spectroscopy and x-ray diffraction

The orientational order parameters 〈P2〉 and 〈P4〉 of the ferroelectric, de Vries–type liquid crystal 9HL have been determined in the SmA* and SmC* phases by means of polarized Raman spectroscopy, and in the SmA* phase using x-ray diffraction. Quantum density functional theory predicts Raman spectra for 9HL that are in good agreement with the observations and indicates that the strong Raman band probed in the experiment corresponds to the uniaxial, coupled vibration of the three phenyl rings along the molecular long axis. The magnitudes of the orientational order parameters obtained in the Raman and x-ray experiments differ dramatically from each other, a discrepancy that is resolved by considering that the two techniques probe the orientational distributions of different molecular axes. We have developed a systematic procedure in which we calculate the angle between these axes and rescale the orientational order parameters obtained from x-ray scattering with results that are then in good agreement with the Raman data. At least in the case of 9HL, the results obtained by both techniques support a “sugar loaf” orientational distribution in the SmA* phase with no qualitative difference to conventional smectics A. The role of individual molecular fragments in promoting de Vries–type behavior is considered

The role of physical activity in the treatment of type 2 diabetes

Type 2 diabetes belongs to the group of civilization diseases of the 21st century. In Poland, over 3 million people suffer from diabetes, including 1 million being undiagnosed. In the initial stage, this disease does not hinder functioning in everyday life, often people get to know about being affected by this disease during other diagnostic tests related to another illness. As diabetes develops, there may be numerous complications, including: retinopathy, nephropathy, neuropathy, cerebrovascular disease, ischemic heart disease, peripheral artery disease. Untreated type 2 diabetes can lead to death, so it is very important to start treatment quickly. The aim of therapy is to balance carbohydrate and lipid metabolism, achieve optimal blood pressure, proper body weight, and prevent complications. This can be achieved by combining a properly selected diet, physical activity and pharmacotherapy

Possibilities of physiotherapy in Chronic Obstructive Lung Disease

COPD is a progressive disease of the respiratory system that, if untreated, decreases the quality of life of patients. The treatment of COPD is mainly based on the use of bronchodilators and the use of appropriate exercise training. Numerous studies show that properly selected physical effort has a beneficial effect on improving exercise tolerance, spirometric indexes and reducing dyspnoea in patients. Treatments such as: postural drainage, inhalations, chest patting and learning an effective cough also contribute to improving the quality of life in patients suffering from COPD. The appearance of special NIV apparatus very effectively facilitates lung ventilation, and most importantly - allows the patient to support treatment at home