37 research outputs found
Domestic Dog and Cat Bites: Epidemiology and Analysis of 823 Cases over the Last 5 Years
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Anticoagulation Therapy in Microsurgery: A Review
The advent of microsurgical tissue transfer including replantation greatly has expanded the scope of reconstructive surgery. There are few recent innovations in anticoagulation therapies for microsurgery, however, and anastomotic thrombosis remains an occasional cause of surgical failure. No consensus exists on the ideal anticoagulation protocol for microsurgery. This article reviews major pharmacologic modalities of anticoagulation, delineates the mechanism of action and study of efficacy of each agent, and compares the risks and benefits of popular anticoagulation therapies. Finally, it examines available human outcomes–based data and attempts to provide a glimpse of the future direction of microsurgical anticoagulation research
The Anatomy behind Adverse Events in Hand Volumizing Procedures: Retrospective Evaluations of 11 Years of Experience
Background: To retrospectively evaluate the rate of adverse events after hand volumizing procedures using a calcium hydroxylapatite product and to investigate the relationship between injector used (i.e., needle versus cannula) and technique applied (i.e., bolus, tenting, proximal-to-distal fanning, distal-toproximal single line). Methods: Two hundred twenty individuals, including 214 women (97.3 percent) aged 52.3 +/- 11.4 years, treated bilaterally for hand rejuvenation were investigated between the years 2006 and 2017. Cadaveric dissections (n = 12), fluoroscopic (n = 4), ultrasound (n = 22), and computed tomographic (n = 4) imaging were also performed to guide conclusions. Results: Thirty-two of 440 hands (7.3 percent) developed adverse events within the first 15 days, with swelling in 11 (5 percent), pain in four (1.8 percent), erythema in three (1.4 percent), and discoloration in one (0.5 percent). Using a needle (versus a cannula) was significantly related to the occurrence of adverse events (OR, 7.57;95 percent CI, 3.76 to 15.24;p < 0.001). The proximalto- distal fanning technique with access to the dorsal superficial lamina was identified as a safer application technique, with each of the other techniques having a significantly increased odds ratio for adverse events: bolus technique (OR, 26.9;95 percent CI, 6.87 to 105.2;p < 0.001), tenting technique (OR, 24.73;95 percent CI, 7.48 to 81.76;p < 0.001), and single-line technique (OR, 26.68;95 percent CI, 7.45 to 95.48;p < 0.001). Conclusions: The results of this study support the use of cannula versus needle and the proximal-to-distal fanning technique. The underlying anatomy supports the positioning of the material into the subdermal space, which can be identified less than 1 mm deep to the skin surface, and is termed the dorsal superficial lamina
Blinded Evaluation of Hyaluronic Acid Hand Filler Injections and Effects on First Impressions
Anatomic, histologic, and ultrasound analyses of the dorsum of the hand for volumetric rejuvenation
Does seeding density affect in vitro mineral nodules formation in novel composite scaffolds?
10.1002/jbm.a.30685Journal of Biomedical Materials Research - Part A781183-193JBMR