Feasability of Preventing Encrustation of Urinary Catheters

Colonization of urinary catheters by bacteria which produce urease leads to an increase in urine pH, followed by deposition of the minerals struvite and hydroxyapatite. Adhesion of these encrusting deposits can be reduced, but not prevented, by using catheters with a smooth surface finish. Chemical methods for preventing encrustation are not completely satisfactory. A better way of preventing encrustation would be to prevent colonization of the catheter by bacteria. This might be achieved by controlled release of antimicrobial agents directly into the urine from the catheter itself. Preliminary experiments have demonstrated the feasibility of controlled release from solid silicone. However, a simpler approach is diffusion of an antimicrobial agent from a solution within the retention balloon of the catheter. Further experiments are required to determine the concentrations required and whether they are achievable in practice

Changes in Congressional Oversight

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68007/2/10.1177_000276427902200504.pd

'I would rather die': reasons given by 16-year-olds for not continuing their study of mathematics

Improving participation rates in specialist mathematics after the subject ceases to be compulsory at age 16 is part of government policy in England. This article provides independent and recent support for earlier findings concerning reasons for non- participation, based on free response and closed items in a questionnaire with a sample of over 1500 students in 17 schools, close to the moment of choice. The analysis supports findings that perceived difficulty and lack of confidence are important reasons for students not continuing with mathematics, and that perceived dislike and boredom, and lack of relevance, are also factors. There is a close relationship between reasons for non-participation and predicted grade, and a weaker relation to gender. An analysis of the effects of schools, demonstrates that enjoyment is the main factor differentiating schools with high and low participation indices. Building on discussion of these findings, ways of improving participation are briefly suggested

Further Education: Social Mobility, Skills and Second Chances

This report looks at data analysis which has uncovered good returns to learning at all levels of FE and challenges previous findings from survey-based studies that estimated insignificant, or even negative, returns to learning at level 2 and below. In the accompanying policy comment Professor Peter Unwin from the Centre welcomes the recent move away from the almost exclusive focus on more academic learning within HE over recent decades to a focus on apprenticeship learning. He argues that some of the greatest opportunities for boosting UK productivity will only be achieved if we can unlock the potential of those who have innate ability, but are not able to make the most of this, as they are born to levels of disadvantage that mean they are more likely to give up on education at an early age. FE, he argues, takes the most disadvantaged on the longest educational journeys

Robotic automation in computer controlled polishing

We first present a Case Study – the manufacture of 1.4 m prototype mirror-segments for the European Extremely Large Telescope, undertaken by the National Facility for Ultra Precision Surfaces, at the OpTIC facility operated by Glyndwr University. Scale-up to serial-manufacture demands delivery of a 1.4 m off-axis aspheric hexagonal segment with surface precision < 10 nm RMS every four days, compared with a typical year or more for an one-off part. This requires a radically-new approach to large optics fabrication, which will inevitably propagate into wider industrial optics. We report on how these ambitious requirements have stimulated an investigation into the synergy between robots and computer numerically controlled (‘CNC’) polishing machines for optical fabrication. The objective was not to assess which is superior. Rather, it was to understand for the first time their complementary properties, leading us to operate them together as a unit, integrated in hardware and software. Three key areas are reported. First is the novel use of robots to automate currently-manual operations on CNC polishing machines, to improve work-throughput, mitigate risk of damage to parts, and reduce dependence on highly-skilled staff. Second is the use of robots to pre-process surfaces prior to CNC polishing, to reduce total process time. The third draws the threads together, describing our vision of the automated manufacturing cell, where the operator interacts at cell rather than machine level. This promises to deliver a step-change in end-to-end manufacturing times and costs, compared with either platform used on its own or, indeed, the state-of-the-art used elsewhere

Contacting the spirits of the dead: paranormal belief and the teenage worldview

A number of previous studies have examined both the overall level of belief expressed by young people in the paranormal and the major demographic predictors of such belief. Building on this research tradition, the present study examines how one specific paranormal belief concerning contact with the spirits of the dead integrates with the wider teenage worldview. Data provided by 33,982 pupils age 13 to 15 years throughout England and Wales demonstrated that almost one in three young people (31%) believed that it is possible to contact the spirits of the dead. Compared with young people who did not share this belief, the young people who believed in the possibility of contacting the spirits of the dead displayed lower psychological wellbeing, higher anxiety, greater isolation, greater alienation, less positive social attitudes, and less socially conforming lifestyles. Overall, paranormal beliefs seem to be associated with a less healthy worldview, in both personal and social terms

A study of decomposition methods for refinement of H + -ZSM5 zeolite with powder diffraction data

Abstract. Profile and integrated intensity decomposition refinements have been carried out on H+ -ZSM5 X-ray powder diffractometer data (110 structural parameters). This compound is a zeolite catalyst. The Si04 tetrahedra were constrained towards regularity. Chemically sensible results and good fits between observed and calculated profiles and integrated intensities were obtained. It is concluded that larger structures (100-150 structural variables) can be refined from conventional X-ray powder diffractometer data with either of these methods if appropriate geometrical constraints are applied

Exploring the speed and performance of molecular replacement with AMPLE using QUARK ab initio protein models

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/110744/1/S1399004714025784.pd

Around the tangent cone theorem

A cornerstone of the theory of cohomology jump loci is the Tangent Cone theorem, which relates the behavior around the origin of the characteristic and resonance varieties of a space. We revisit this theorem, in both the algebraic setting provided by cdga models, and in the topological setting provided by fundamental groups and cohomology rings. The general theory is illustrated with several classes of examples from geometry and topology: smooth quasi-projective varieties, complex hyperplane arrangements and their Milnor fibers, configuration spaces, and elliptic arrangements.Comment: 39 pages; to appear in the proceedings of the Configurations Spaces Conference (Cortona 2014), Springer INdAM serie