34 research outputs found
Reliability and fault tolerance in the European ADS project
After an introduction to the theory of reliability, this paper focuses on a
description of the linear proton accelerator proposed for the European ADS
demonstration project. Design issues are discussed and examples of cases of
fault tolerance are given.Comment: 14 pages, contribution to the CAS - CERN Accelerator School: Course
on High Power Hadron Machines; 24 May - 2 Jun 2011, Bilbao, Spai
Cyclodipeptide synthases, a family of class-I aminoacyl-tRNA synthetase-like enzymes involved in non-ribosomal peptide synthesis
Cyclodipeptide synthases (CDPSs) belong to a newly defined family of enzymes that use aminoacyl-tRNAs (aa-tRNAs) as substrates to synthesize the two peptide bonds of various cyclodipeptides, which are the precursors of many natural products with noteworthy biological activities. Here, we describe the crystal structure of AlbC, a CDPS from Streptomyces noursei. The AlbC structure consists of a monomer containing a Rossmann-fold domain. Strikingly, it is highly similar to the catalytic domain of class-I aminoacyl-tRNA synthetases (aaRSs), especially class-Ic TyrRSs and TrpRSs. AlbC contains a deep pocket, highly conserved among CDPSs. Site-directed mutagenesis studies indicate that this pocket accommodates the aminoacyl moiety of the aa-tRNA substrate in a way similar to that used by TyrRSs to recognize their tyrosine substrates. These studies also suggest that the tRNA moiety of the aa-tRNA interacts with AlbC via at least one patch of basic residues, which is conserved among CDPSs but not present in class-Ic aaRSs. AlbC catalyses its two-substrate reaction via a ping-pong mechanism with a covalent intermediate in which l-Phe is shown to be transferred from Phe-tRNAPhe to an active serine. These findings provide insight into the molecular bases of the interactions between CDPSs and their aa-tRNAs substrates, and the catalytic mechanism used by CDPSs to achieve the non-ribosomal synthesis of cyclodipeptides
ETUDE DE CAVITES SUPRACONDUCTRICES POUR LES ACCELERATEURS DE PROTONS DE FORTE PUISSANCE
ORSAY-PARIS 11-BU Sciences (914712101) / SudocSudocFranceF
Dynamic compensation of an rf cavity failure in a superconducting linac
An accelerator driven system (ADS) for transmutation of nuclear waste typically requires a 600 MeV–1 GeV accelerator delivering a proton flux of a few mA for demonstrators, and of a few tens of mA for large industrial systems. Such a machine belongs to the category of the high-power proton accelerators, with an additional requirement for exceptional “reliability”: because of the induced thermal stress to the subcritical core, the number of unwanted “beam trips” should not exceed a few per year, a specification that is several orders of magnitude above usual performance. In order to meet this extremely high reliability, the accelerator needs to implement, to the maximum possible extent, a fault-tolerance strategy that would allow beam operation in the presence of most of the envisaged faults that could occur in its beam line components, and in particular rf systems’ failures. This document describes the results of the simulations performed for the analysis of the fault-tolerance capability of the XT-ADS superconducting linac in the case of an rf cavity failure. A new simulation tool, mixing transient rf behavior of the accelerating cavities with full 6D description of the beam dynamics, has been developed for this purpose. Fast fault-recovery scenarios are proposed, and required research and development is identified
Investigation of different layouts for the EURISOL driver
This technical note describes, first, the main parameters of the driver optimised for the protons and, in a second part, shows optimised layouts which include the additional features
The Myrrha linear accelerator
Accelerator Driven Systems (ADS) are promising tools for the efficient transmutation of nuclear waste products in dedicated industrial installations, called transmuters. The Myrrha project at Mol, Belgium, placed itself on the path towards these applications with a multipurpose and versatile system based on a liquid PbBi (LBE) cooled fast reactor (80 MWth) which may be operated in both critical and subcritical modes. In the latter case the core is fed by spallation neutrons obtained from a 600 MeV proton beam hitting the LBE coolant/target. The accelerator providing this beam is a high intensity CW superconducting linac which is laid out for the highest achievable reliability. The combination of a parallel redundant and of a fault tolerant scheme should allow obtaining an MTBF value in excess of 250 hours that is required for optimal integrity and successful operation of the ADS. Myrrha is expected to be operational in 2023. The forthcoming 4-year period is fully dedicated to R&D activities, and in the field of the accelerator they are strongly focused on the reliability aspects and on the proper shaping of the beam trip spectrum
Control System Developments for the MYRRHA Linac
International audienceThe goal of the MYRRHA project is to demonstrate the technical feasibility of transmutation in a 100 MWth Accelerator Driven System by building a new flexible irradiation complex in Mol (Belgium). The MYRRHA facility requires a 600 MeV linear accelerator delivering a maximum proton flux of 4 mA in continuous operation, with an additional requirement for exceptional reliability. The control system of the future MYRRHA linac will have an essential role to play in this extreme reliability scenario. On the one hand the intrinsic reliability of the entire control system must be ensured. On the other hand control system will have to take up very high level duties of complex decision taking. This paper summarizes the ongoing developments for the concept design of such a control system. The related experimental activities performed and planned around the MYRRHA injector platform (ECR ion source + LEBT + RFQ) will also be described