Spatio-Temporal Tuples Transformer for Skeleton-Based Action Recognition

Capturing the dependencies between joints is critical in skeleton-based action recognition task. Transformer shows great potential to model the correlation of important joints. However, the existing Transformer-based methods cannot capture the correlation of different joints between frames, which the correlation is very useful since different body parts (such as the arms and legs in "long jump") between adjacent frames move together. Focus on this problem, A novel spatio-temporal tuples Transformer (STTFormer) method is proposed. The skeleton sequence is divided into several parts, and several consecutive frames contained in each part are encoded. And then a spatio-temporal tuples self-attention module is proposed to capture the relationship of different joints in consecutive frames. In addition, a feature aggregation module is introduced between non-adjacent frames to enhance the ability to distinguish similar actions. Compared with the state-of-the-art methods, our method achieves better performance on two large-scale datasets.Comment: 14 pages, 5 figure

Adaptive transmission in heterogeneous networks

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/166243/1/cmu2bf00018.pd

Verrucisidinol and Verrucosidinol Acetate, Two Pyrone-Type Polyketides Isolated from a Marine Derived Fungus, Penicillium aurantiogriseum

The new secondary metabolites verrucosidinol (1) and its derivative verrucosidinol acetate (2), together with a potent neurotoxin verrucosidin (3), a congener norverrucosidin (4) and a mixture of two known phytotoxic metabolites terrestric acids (5 and 6), were isolated from the marine derived fungus Penicillium aurantiogriseum. Verrucosidinol has a ring-opened ethylene oxide moiety in the polyene α-pyrone skeleton, and verrucosidinol acetate is its acetate derivative. The chemical structures were determined by comparing with literature data and a combination of spectroscopic techniques, including high resolution mass spectrum and two-dimentional nuclear magnetic resonance spectroscopic analysis

Taiji Data Challenge for Exploring Gravitational Wave Universe

The direct observation of gravitational waves (GWs) opens a new window for exploring new physics from quanta to cosmos and provides a new tool for probing the evolution of universe. GWs detection in space covers a broad spectrum ranging over more than four orders of magnitude and enables us to study rich physical and astronomical phenomena. Taiji is a proposed space-based GW detection mission that will be launched in the 2030s. Taiji will be exposed to numerous overlapping and persistent GW signals buried in the foreground and background, posing various data analysis challenges. In order to empower potential scientific discoveries, the Mock LISA Data Challenge and the LISA Data Challenge (LDC) were developed. While LDC provides a baseline framework, the first LDC needs to be updated with more realistic simulations and adjusted detector responses for Taiji's constellation. In this paper, we review the scientific objectives and the roadmap for Taiji, as well as the technical difficulties in data analysis and the data generation strategy, and present the associated data challenges. In contrast to LDC, we utilize second-order Keplerian orbit and second-generation time delay interferometry techniques. Additionally, we employ a new model for the extreme-mass-ratio inspiral waveform and stochastic GW background spectrum, which enables us to test general relativity and measure the non-Gaussianity of curvature perturbations. Furthermore, we present a comprehensive showcase of parameter estimation using a toy dataset. This showcase not only demonstrates the scientific potential of the Taiji Data Challenge but also serves to validate the effectiveness of the pipeline. As the first data challenge for Taiji, we aim to build an open ground for data analysis related to Taiji sources and sciences. More details can be found on the official website at http://taiji-tdc.ictp-ap.org.Comment: 15 pages, 3 figure

Retrieving Soil and Vegetation Temperatures From Dual-Angle and Multipixel Satellite Observations

Land surface component temperatures (LSCTs), i.e., the temperatures of soil and vegetation, are important parameters in many applications, such as estimating evapotranspiration and monitoring droughts. However, the multiangle algorithm is affected due to different spatial resolution between nadir and oblique views. Therefore, we propose a combined retrieval algorithm that uses dual-angle and multipixel observations together. The sea and land surface temperature radiometer onboard ESA\u27s Sentinel-3 satellite allows for quasi-synchronous dual-angle observations, from which LSCTs can be retrieved using dual-angle and multipixel algorithms. The better performance of the combined algorithm is demonstrated using a sensitivity analysis based on a synthetic dataset. The spatial errors in the oblique view due to different spatial resolution can reach 4.5 K and have a large effect on the multiangle algorithm. The introduction of multipixel information in a window can reduce the effect of such spatial errors, and the retrieval results of LSCTs can be further improved by using multiangle information for a pixel. In the validation, the proposed combined algorithm performed better, with LSCT root mean squared errors of 3.09 K and 1.91 K for soil and vegetation at a grass site, respectively, and corresponding values of 3.71 K and 3.42 K at a sparse forest site, respectively. Considering that the temperature differences between components can reach 20 K, the results confirm that, in addition to a pixel-average LST, the combined retrieval algorithm can provide information on LSCTs. This article demonstrates the potential of utilizing additional information sources for better LSCT results, which makes the presented combined strategy a promising option for deriving large-scale LSCT products

Leveraging GPT-4 for Food Effect Summarization to Enhance Product-Specific Guidance Development via Iterative Prompting

Food effect summarization from New Drug Application (NDA) is an essential component of product-specific guidance (PSG) development and assessment. However, manual summarization of food effect from extensive drug application review documents is time-consuming, which arouses a need to develop automated methods. Recent advances in large language models (LLMs) such as ChatGPT and GPT-4, have demonstrated great potential in improving the effectiveness of automated text summarization, but its ability regarding the accuracy in summarizing food effect for PSG assessment remains unclear. In this study, we introduce a simple yet effective approach, iterative prompting, which allows one to interact with ChatGPT or GPT-4 more effectively and efficiently through multi-turn interaction. Specifically, we propose a three-turn iterative prompting approach to food effect summarization in which the keyword-focused and length-controlled prompts are respectively provided in consecutive turns to refine the quality of the generated summary. We conduct a series of extensive evaluations, ranging from automated metrics to FDA professionals and even evaluation by GPT-4, on 100 NDA review documents selected over the past five years. We observe that the summary quality is progressively improved throughout the process. Moreover, we find that GPT-4 performs better than ChatGPT, as evaluated by FDA professionals (43% vs. 12%) and GPT-4 (64% vs. 35%). Importantly, all the FDA professionals unanimously rated that 85% of the summaries generated by GPT-4 are factually consistent with the golden reference summary, a finding further supported by GPT-4 rating of 72% consistency. These results strongly suggest a great potential for GPT-4 to draft food effect summaries that could be reviewed by FDA professionals, thereby improving the efficiency of PSG assessment cycle and promoting the generic drug product development.Comment: 22 pages, 6 figure