63 research outputs found

    Teacher's experiences of the teaching of personal capabilities through the science curriculum.

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    This thesis represents the study of teachers' perceptions and experiences of the teaching of Personal Capabilities (PCs) through the Science curriculum. It documents the process by which teachers were successfully enabled to incorporate the teaching of PCs through the Science curriculum. An action research methodology provided the basis for the development of the study which benefited from flexible, collaborative partnerships between teachers and the researcher. Facilitation and support prompted action and continuous reflection on research interventions, their outcomes and influence on pedagogy, student development and learning. Emphasis on regular teacher-researcher interactions during curriculum innovation had significant implications on teachers' professional development, and was critical in affecting pedagogic change. Collaborative partnerships emerged as a powerful tool for understanding the teaching and learning of PCs. Semi-structured interviews and questionnaires, classroom observations, reflective logbook entries and discussions formed the main sources of data, represented in case studies which provide contextualised representations of teacher activity. Using ten operationally-defined PCs, it is shown that students' development can be enhanced through the Science curriculum. A process model including: knowing, self-assessing, action planning, acting and reviewing, illustrates the teachers' and students' actions during PC development. Strategies for facilitating students' PC improvement are illustrative of the teachers' modified pedagogic approaches to subject teaching, which encourage self-awareness and prompt behavioural change. Findings from this study suggest further research and provide recommendations for policy makers, teachers and educational researchers, highlighting the constraining nature of current National Curriculum (NC) assessment strategies

    Immortalized Mouse Inner Ear Cell Lines Demonstrate a Role for Chemokines in Promoting the Growth of Developing Statoacoustic Ganglion Neurons

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    The target-derived factors necessary for promoting initial outgrowth from the statoacoustic ganglion (SAG) to the inner ear have not been fully characterized. In the present study, conditioned medium from embryonic Immortomouse inner ear cell lines that maintain many characteristics of developing inner ear sensory epithelia were screened for neurite-promoting activity. Conditioned medium found to be positive for promoting SAG neurite outgrowth and neuronal survival was then tested for the presence of chemokines, molecules that have not previously been investigated for promoting SAG outgrowth. One candidate molecule, monocyte chemotactic protein 1 (MCP-1), was detected in the conditioned medium and subsequently localized to mouse hair cells by immunocytochemistry. In vitro studies demonstrated that function-blocking MCP-1 antibodies decreased the amount of SAG neurite outgrowth induced by the conditioned medium and that subsequent addition of MCP-1 protein was able to promote outgrowth when added to the antibody-treated conditioned medium. The use of the Immortomouse cell lines proved valuable in identifying this candidate cofactor that promotes outgrowth of early-stage SAG nerve fibers and is expressed in embryonic hair cells.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/41388/1/10162_2005_Article_13.pd

    The Ups and Downs in Women's Employment: Shifting Composition or Behavior from 1970 to 2010?

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    This paper tracks factors contributing to the ups and downs in women’s employment from 1970 to 2010 using regression decompositions focusing on whether changes are due to shifts in the means (composition of women) or due to shifts in coefficients (inclinations of women to work for pay). Compositional shifts in education exerted a positive effect on women’s employment across all decades, while shifts in the composition of other family income, particularly at the highest deciles, depressed married women’s employment over the 1990s contributing to the slowdown in this decade. A positive coefficient effect of education was found in all decades, except the 1990s, when the effect was negative, depressing women’s employment. Further, positive coefficient results for other family income at the highest deciles bolstered married women’s employment over the 1990s. Models are run separately for married and single women demonstrating the varying results of other family income by marital status. This research was supported in part by an Upjohn Institute Early Career Research Award

    Three New Eclipsing White-dwarf - M-dwarf Binaries Discovered in a Search for Transiting Planets Around M-dwarfs

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    We present three new eclipsing white-dwarf / M-dwarf binary systems discovered during a search for transiting planets around M-dwarfs. Unlike most known eclipsing systems of this type, the optical and infrared emission is dominated by the M-dwarf components, and the systems have optical colors and discovery light curves consistent with being Jupiter-radius transiting planets around early M-dwarfs. We detail the PTF/M-dwarf transiting planet survey, part of the Palomar Transient Factory (PTF). We present a Graphics Processing Unit (GPU)-based box-least-squares search for transits that runs approximately 8X faster than similar algorithms implemented on general purpose systems. For the discovered systems, we decompose low-resolution spectra of the systems into white-dwarf and M-dwarf components, and use radial velocity measurements and cooling models to estimate masses and radii for the white dwarfs. The systems are compact, with periods between 0.35 and 0.45 days and semimajor axes of approximately 2 solar radii (0.01 AU). We use the Robo-AO laser guide star adaptive optics system to tentatively identify one of the objects as a triple system. We also use high-cadence photometry to put an upper limit on the white dwarf radius of 0.025 solar radii (95% confidence) in one of the systems. We estimate that 0.08% (90% confidence) of M-dwarfs are in these short-period, post-common-envelope white-dwarf / M-dwarf binaries where the optical light is dominated by the M-dwarf. Similar eclipsing binary systems can have arbitrarily small eclipse depths in red bands and generate plausible small-planet-transit light curves. As such, these systems are a source of false positives for M-dwarf transiting planet searches. We present several ways to rapidly distinguish these binaries from transiting planet systems.Comment: 14 pages, 14 figures, submitted to Ap

    Abstracts from the Food Allergy and Anaphylaxis Meeting 2016

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    Developmental Neurobiology

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    Development of the Inner Ear

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