5 research outputs found
édition associative française : notes pour une étude (L\u27)
Mémoire du Master 2 Cultures de l\u27écrit et de l\u27image portant sur l\u27édition indépendante et plus particuliÚrement sur l\u27édition associative en France
Rencontres Henri-Jean Martin : vingt ans de patrimoine
Enregistrements vidéos des Rencontres Henri-Jean Martin qui se sont tenues les 8 et 9 octobre 2012 à l\u27enssib
Telomeres are shorter in myocardial infarction patients compared to healthy subjects: correlation with environmental risk factors
Shorter telomeres have been reported in premature myocardial infarction (MI) patients. Our work aimed at confirming the association of shorter telomere with MI in two caseâcontrol studies and in familial hypercholesterolemia (FH) patients with coronary heart disease (CHD). The HIFMECH study compared 598 white male patients (<60Â years) who survived a first MI and 653 age-matched controls from North and South Europe. Additionally, from the UK, 413 coronary artery bypass graft (CABG) patients and two groups of 367 and 94 FH patients, of whom 145 and 17 respectively had premature CHD, were recruited. Leukocyte telomere length (LTL) was measured using a real-time polymerase chain reaction-based method. In HIFMECH, LTL was significantly shorter in subjects from the North (7.99Â kb, SD 4.51) compared to the South (8.27Â kb, SD 4.14; pâ=â0.02) and in cases (7.85Â kb, SD 4.01) compared to controls (8.04Â kb, SD 4.46; pâ=â0.04). In the CABG study, LTL was significantly shorter (6.89Â kb, SD 4.14) compared to the HIFMECH UK controls (7.53, SD 5.29; pâ=â0.007). In both samples of FH patients, LTL was shorter in those with CHD (overall 8.68Â kb, SD 4.65) compared to the non-CHD subjects (9.23Â kb, SD 4.83; pâ=â0.012). Apart from a consistent negative correlation with age, LTL was not associated across studies with any measured CHD risk factors. The present data confirms that subjects with CHD have shorter telomeres than controls and extends this to those with monogenic and polygenic forms of CHD
Vingt ans de recherche sur le patrimoine : synthĂšse
SynthÚse sur vingt ans de recherche sur le patrimoine présentée par des élÚves et étudiants de l\u27enssib lors des Rencontres Henri-Jean Martin le 9 octobre 2012 à l\u27enssib