AYURVEDA MANAGEMENT OF DYSFUNCTIONAL UTERINE BLEEDING - A CASE REPORT

A 41yrs. female patient came to our clinic outpatient department Gune Ayurved College, Ahmednagar, Maharashtra with complaints of excessive vaginal bleeding. The case was diagnosed as Adhoga Raktapitta by Ayurvedic nidan, symptomatic relief by Stambhana dravyas was not ultimate solution to avoid hysterectomy. This case was successfully treated on basic principles of Ayurveda Panchbhautic chikitsa. A symptom free follow up in this case was noticed after completion of 8 months Ayurved therapy. The treatment options offered here primary aim at reducing Kshardharmiushnata in the body with Parthivdravya and increasing uterine tone (Dharana).Dysfunctional Uterine Bleeding is defined as a state of abnormal uterine bleeding without any clinically detectable organic, systemic & iatrogenic cause. Heavy Bleeding interferes with womens physical emotional, social & material quality & life. Currently DUB is defined as a state of abnormal uterine bleeding following anovulation due to dysfunction & hypothalamo-pituitary-ovarian axis endocrine origin. It is more prevalent in premenopausal & abortion. Overall 70%-80% results of endometrial ablation or resection amongst 10% of the patients need hysterectomy. In present case study we are presenting here with more than 2 yrs. history of Dysfunctional Uterine Bleeding without any response from modern medicine.

Quantitative Analysis of Propranolol Hydrochloride by High Performance Thin Layer Chromatography

A simple, accurate and precise HPTLC method has been developed for estimation of propranolol hydrochloride from bulk drug and tablet formulations. The separation was achieved on TLC plates using appropriate solvent system. The spots so developed were densitometrically scanned at 290 nm. The linearity of the method was found to be within the concentration range of 200–2000 ng/spot. The validation parameters, tested in accordance with the requirements of ICH guidelines, prove the suitability of this method. The method was successively applied for determination of drug in tablets, wherein, no interference from tablet excipients was observed

Validated HPTLC Method for Simultaneous Determination of Quinapril Hydrochloride and Hydrochlorothiazide in a Tablet Dosage Form

Quinapril hydrochloride and hydrochlorothiazide were simultaneously determined by HPTLC in pharmaceutical formulations. The drugs were separated on silica gel 60 F254 plates using suitable combination of solvents as mobile phase. The validation parameters, tested in accordance with the requirements of ICH guidelines, prove the suitability of methods