11 research outputs found

    Antinociceptive and Toxicological Effects of Dioclea grandiflora Seed Pod in Mice

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    The acute treatment of mice with an ethanolic extract from the seed pod of Dioclea grandiflora (EDgP) at doses of 75, 150 and 300 mg/kg by intraperitoneal administration produced a significant antinociceptive effect as displayed by the acetic acid-induced writhing test and the formalin test. The antinociception was observed through the first (neurogenic pain) and second (inflammatory pain) phases in the formalin test. The hot plate test did not show an increase in the antinociceptive latency whereas the motor performance was affected by the administration at 300 mg/kg at the beginning (30 minutes) of the observation period but not at later periods (60 and 120 minutes). These results suggest that EDgP has a central antinociceptive action and a possible anti-inflammatory activity in mice

    Constituents of Ipomoea horrida Humber ex ducke: spectroscopic identification of the flavonoids

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    As part of a systematic investigation of the Ipomoea species of Northeastern Brazil, a mixture of 7,4'-di­O-methylkaempferol and 7,3',4'-tri-O­methylquercetin were identified in extracts obtained from the aerial parts of Ipomoea horrida

    Constituents of Encyclia longifolia Schltr. (Orchidaceae)

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    A detailed chemical analysis of the non-volatile secondary metabolites of Encyclia longifolia Schltr. syn. Epidendrum longifolium Barb. Rodr. was carried out in an attempt to lend a chemotaxonomic support for the recent separation of the genus Encyclia into Encyclia Hook and Prosthechea Knowles & Westc
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