880 research outputs found
Second-order Democratic Aggregation
Aggregated second-order features extracted from deep convolutional networks
have been shown to be effective for texture generation, fine-grained
recognition, material classification, and scene understanding. In this paper,
we study a class of orderless aggregation functions designed to minimize
interference or equalize contributions in the context of second-order features
and we show that they can be computed just as efficiently as their first-order
counterparts and they have favorable properties over aggregation by summation.
Another line of work has shown that matrix power normalization after
aggregation can significantly improve the generalization of second-order
representations. We show that matrix power normalization implicitly equalizes
contributions during aggregation thus establishing a connection between matrix
normalization techniques and prior work on minimizing interference. Based on
the analysis we present {\gamma}-democratic aggregators that interpolate
between sum ({\gamma}=1) and democratic pooling ({\gamma}=0) outperforming both
on several classification tasks. Moreover, unlike power normalization, the
{\gamma}-democratic aggregations can be computed in a low dimensional space by
sketching that allows the use of very high-dimensional second-order features.
This results in a state-of-the-art performance on several datasets
Self-Titrating Anticoagulant Nanocomplexes That Restore Homeostatic Regulation of the Coagulation Cascade
Antithrombotic therapy is a critical portion of the treatment regime for a number of life-threatening conditions, including cardiovascular disease, stroke, and cancer; yet, proper clinical management of anticoagulation remains a challenge because existing agents increase the propensity for bleeding in patients. Here, we describe the development of a bioresponsive peptide–polysaccharide nanocomplex that utilizes a negative feedback mechanism to self-titrate the release of anticoagulant in response to varying levels of coagulation activity. This nanoscale self-titrating activatable therapeutic, or nanoSTAT, consists of a cationic thrombin-cleavable peptide and heparin, an anionic polysaccharide and widely used clinical anticoagulant. Under nonthrombotic conditions, nanoSTATs circulate inactively, neither releasing anticoagulant nor significantly prolonging bleeding time. However, in response to life-threatening pulmonary embolism, nanoSTATs locally release their drug payload and prevent thrombosis. This autonomous negative feedback regulator may improve antithrombotic therapy by increasing the therapeutic window and decreasing the bleeding risk of anticoagulants.National Institutes of Health (U.S.) (R01CA124427-01)National Cancer Institute (U.S.) (U54CA119349)National Cancer Institute (U.S.) (U54CA119335)National Cancer Institute (U.S.) (Center of Cancer Nanotechnology Excellence at MIT-Harvard U54CA151884)David & Lucile Packard Foundation (Fellowship)David H. Koch Institute for Integrative Cancer Research at MIT (Marie D. and Pierre Casimir-Lambert Fund)National Cancer Institute (U.S.) (Koch Institute Support (Core) Grant P30-CA14051)MIT-Harvard Center of Cancer Nanotechnology Excellence (5 U54 CA151884-03)National Institutes of Health (U.S.). Medical Scientist Training Program (T32GM007753)National Institutes of Health (U.S.) (Ruth L. Kirschstein National Research Service Award F32CA159496-02)Burroughs Wellcome Fund (Career Award at the Scientific Interface
Additivity and non-additivity of multipartite entanglement measures
We study the additivity property of three multipartite entanglement measures,
i.e. the geometric measure of entanglement (GM), the relative entropy of
entanglement and the logarithmic global robustness. First, we show the
additivity of GM of multipartite states with real and non-negative entries in
the computational basis. Many states of experimental and theoretical interests
have this property, e.g. Bell diagonal states, maximally correlated generalized
Bell diagonal states, generalized Dicke states, the Smolin state, and the
generalization of D\"{u}r's multipartite bound entangled states. We also prove
the additivity of other two measures for some of these examples. Second, we
show the non-additivity of GM of all antisymmetric states of three or more
parties, and provide a unified explanation of the non-additivity of the three
measures of the antisymmetric projector states. In particular, we derive
analytical formulae of the three measures of one copy and two copies of the
antisymmetric projector states respectively. Third, we show, with a statistical
approach, that almost all multipartite pure states with sufficiently large
number of parties are nearly maximally entangled with respect to GM and
relative entropy of entanglement. However, their GM is not strong additive;
what's more surprising, for generic pure states with real entries in the
computational basis, GM of one copy and two copies, respectively, are almost
equal. Hence, more states may be suitable for universal quantum computation, if
measurements can be performed on two copies of the resource states. We also
show that almost all multipartite pure states cannot be produced reversibly
with the combination multipartite GHZ states under asymptotic LOCC, unless
relative entropy of entanglement is non-additive for generic multipartite pure
states.Comment: 45 pages, 4 figures. Proposition 23 and Theorem 24 are revised by
correcting a minor error from Eq. (A.2), (A.3) and (A.4) in the published
version. The abstract, introduction, and summary are also revised. All other
conclusions are unchange
Analyzing power measurements in high‐P2∥ p‐p elastic scattering
The analyzing power in 28 GeV/c proton/proton elastic scattering was measured at P2∥=5.95 and 6.56 (GeV/c)2 using a polarized proton target and an unpolarized proton beam at the Brookhaven National Laboratory AGS. Results indicate that the analyzing power, A, is rising sharply with P2∥.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87401/2/1123_1.pd
Pion interferometry in Au+Au collisions at = 200 GeV
We present a systematic analysis of two-pion interferometry in Au+Au
collisions at = 200 GeV using the STAR detector at RHIC. We
extract the HBT radii and study their multiplicity, transverse momentum, and
azimuthal angle dependence. The Gaussianess of the correlation function is
studied. Estimates of the geometrical and dynamical structure of the freeze-out
source are extracted by fits with blast wave parameterizations. The expansion
of the source and its relation with the initial energy density distribution is
studied.Comment: 21 pages, 30 figures. As published in Physics Review
Pion interferometry in Au+Au collisions at sqrt[sNN]=200GeV
We present a systematic analysis of two-pion interferometry in Au+Au collisions at sqrt[sNN]=200GeV using the STAR detector at Relativistic Heavy Ion Collider. We extract the Hanbury-Brown and Twiss radii and study their multiplicity, transverse momentum, and azimuthal angle dependence. The Gaussianness of the correlation function is studied. Estimates of the geometrical and dynamical structure of the freeze-out source are extracted by fits with blast-wave parametrizations. The expansion of the source and its relation with the initial energy density distribution is studied
Transverse-momentum dependent modification of dynamic texture in central Au+Au collisions at sqrt(S_NN)=200 GeV
Correlations in the hadron distributions produced in relativistic Au+Au
collisions are studied in the discrete wavelet expansion method. The analysis
is performed in the space of pseudorapidity (|eta| < 1) and azimuth (full 2 pi)
in bins of transverse momentum (p_t) from 0.14 < p_t < 2.1 GeV/c. In peripheral
Au+Au collisions a correlation structure ascribed to mini-jet fragmentation is
observed. It evolves with collision centrality and p_t in a way not seen before
which suggests strong dissipation of minijet fragmentation in the
longitudinally-expanding medium.Comment: 6 pages, 3 figure, accepted as Phys.Rev.C Rapid Communication. This
version fixes journal style issue
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