111 research outputs found
Composing leads-to properties
AbstractCompositionality is of great practical importance when building systems from individual components. Unfortunately, leads-to properties are not, in general, compositional, and theorems describing the special cases where they are, are needed. In this paper, we develop a general theory of compositional leads-to properties, and use it to derive a composition theorem based on the notion of progress sets, where progress sets can be defined in various ways. Appropriate definitions of progress sets yield new results and generalized versions of known theorems
An Algorithm for Distributed Location Management in Networks of Mobile Computers
In a network supporting mobile communication devices, a mechanism to find the location of a device, wherever it may be, is needed. In this paper, we present a distributed algorithm for this purpose along with its formal specification and proof sketch. Inspired by our experiences with Wang's algorithm [9], one goal of this paper is to demonstrate that the process of formalization together with careful attention to abstraction and presentation can yield significant benefits in algorithm design. In this case, we obtained a more regular, general, and robust algorithm with a clearer description. An incidental contribution is a useful theorem for proving progress properties in distributed algorithms that use tokens
Predictive coupled-cluster isomer orderings for some SiC () clusters; A pragmatic comparison between DFT and complete basis limit coupled-cluster benchmarks
The accurate determination of the preferred
isomer is important to guide experimental efforts directed towards synthesizing
SiC nano-wires and related polymer structures which are anticipated to be
highly efficient exciton materials for opto-electronic devices. In order to
definitively identify preferred isomeric structures for silicon carbon
nano-clusters, highly accurate geometries, energies and harmonic zero point
energies have been computed using coupled-cluster theory with systematic
extrapolation to the complete basis limit for set of silicon carbon clusters
ranging in size from SiC to . It is found that
post-MBPT(2) correlation energy plays a significant role in obtaining converged
relative isomer energies, suggesting that predictions using low rung density
functional methods will not have adequate accuracy. Utilizing the best
composite coupled-cluster energy that is still computationally feasible,
entailing a 3-4 SCF and CCSD extrapolation with triple- (T) correlation,
the {\it closo} isomer is identified to be the
preferred isomer in support of previous calculations [J. Chem. Phys. 2015, 142,
034303]. Additionally we have investigated more pragmatic approaches to
obtaining accurate silicon carbide isomer energies, including the use of frozen
natural orbital coupled-cluster theory and several rungs of standard and
double-hybrid density functional theory. Frozen natural orbitals as a way to
compute post MBPT(2) correlation energy is found to be an excellent balance
between efficiency and accuracy
When Will Adolescents Tell Someone About Dating Violence Victimization?
This study examined factors that influence help-seeking among a diverse sample of
adolescents who experienced dating violence. A sample of 57 high school students in
an urban community reported on the prevalence and characteristics of dating violence
in their relationships. Someone observing a dating violence incident and a survivor’s
attaching an emotional meaning to the event significantly influenced adolescents to talk
to someone. When dating violence occurred in isolation, survivors were more likely to
receive no support from others in the aftermath of the incident. Differences between
boys’ and girls’ help-seeking and implications for dating violence intervention and prevention
programming are discussed.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90887/1/Black-Tolman-Callahan-Saunders- Weisz- 2008-When will adolescents tell someone about dating violence VAW.pd
The PEPPHER Approach to Programmability and Performance Portability for Heterogeneous many-core Architectures
International audienceThe European FP7 project PEPPHER is addressing programmability and performance portability for current and emerging heterogeneous many-core archi- tectures. As its main idea, the project proposes a multi-level parallel execution model comprised of potentially parallelized components existing in variants suitable for different types of cores, memory configurations, input characteristics, optimization criteria, and couples this with dynamic and static resource and architecture aware scheduling mechanisms. Crucial to PEPPHER is that components can be made performance aware, allowing for more efficient dynamic and static scheduling on the concrete, available resources. The flexibility provided in the software model, combined with a customizable, heterogeneous, memory and topology aware run-time system is key to efficiently exploiting the resources of each concrete hardware configuration. The project takes a holistic approach, relying on existing paradigms, interfaces, and languages for the parallelization of components, and develops a prototype framework, a methodology for extending the framework, and guidelines for constructing performance portable software and systems  including paths to migration of existing software  for heterogeneous many-core processors. This paper gives a high-level project overview, and presents a specific example showing how the PEPPHER component variant model and resource-aware run-time system enable performance portability of a numerical kernel
ANSI/NISO Z39.99-2017 ResourceSync Framework Specification
This ResourceSync specification describes a synchronization framework for the web consisting of various capabilities that allow third-party systems to remain synchronized with a server’s evolving resources. The capabilities may be combined in a modular manner to meet local or community requirements. This specification also describes how a server should advertise the synchronization capabilities it supports and how third-party systems may discover this information. The specification repurposes the document formats defined by the Sitemap protocol and introduces extensions for them
Autoantibodies to Agrin in Myasthenia Gravis Patients
To determine if patients with myasthenia gravis (MG) have antibodies to agrin, a proteoglycan released by motor neurons and is critical for neuromuscular junction (NMJ) formation, we collected serum samples from 93 patients with MG with known status of antibodies to acetylcholine receptor (AChR), muscle specific kinase (MuSK) and lipoprotein-related 4 (LRP4) and samples from control subjects (healthy individuals and individuals with other diseases). Sera were assayed for antibodies to agrin. We found antibodies to agrin in 7 serum samples of MG patients. None of the 25 healthy controls and none of the 55 control neurological patients had agrin antibodies. Two of the four triple negative MG patients (i.e., no detectable AChR, MuSK or LRP4 antibodies, AChR-/MuSK-/LRP4-) had antibodies against agrin. In addition, agrin antibodies were detected in 5 out of 83 AChR+/MuSK-/LRP4- patients but were not found in the 6 patients with MuSK antibodies (AChR-/MuSK+/LRP4-). Sera from MG patients with agrin antibodies were able to recognize recombinant agrin in conditioned media and in transfected HEK293 cells. These sera also inhibited the agrin-induced MuSK phosphorylation and AChR clustering in muscle cells. Together, these observations indicate that agrin is another autoantigen in patients with MG and agrin autoantibodies may be pathogenic through inhibition of agrin/LRP4/MuSK signaling at the NMJ
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