State of Utah v. Christena White : Appellant\u27s Reply Brief to Appellee\u27s Brief

DISTRICT COURT NO. 021900588FS APPELLANT COURT NO. 20040201-C

A rare cause of acute coronary syndromes in young adults - myeloproliferative neoplasms: A case series

WOS: 000503202800001PubMed: 31784298Introduction: Acute coronary syndromes (ACS) mostly occur in patients with traditional risk factors. Especially in young adults without major cardiovascular (CV) risk factors, one of the less common causes of ACS is myeloproliferative neoplasms (MPNs). Methods: We retrospectively collected data on 11 consecutive patients (nine men, two women, mean age 40.18 +/- 8.4 years) with a diagnosis of MPN who presented with ACS. the demographic characteristics of the study population, type of MPN, clinical manifestations, location of myocardial infarction (MI), coronary angiography findings, complete blood count and other related findings, and treatment strategy before and after diagnosis were analyzed. Results: Six patients were diagnosed with polycythemia vera, four with essential thrombocytosis and one with primary myelofibrosis. A JAK2 mutation was found in nine patients. Mean time to diagnosis of MPN was 2.81 years after presenting ACS and mean age at first MI was 32.9 +/- 6 years. Six patients had no major CV risk factors. Ten patients had anterior MI and one had inferior MI. After initiation of specific treatment for MPN, no recurrent thrombotic events were observed in a mean follow-up of 4 +/- 2.44 years. Conclusions: in young adults presenting with ACS, MPNs should be considered, especially in the absence of atherosclerotic coronary artery lesions. It is also important to pay attention to blood cell count abnormalities seen in intracoronary thrombotic events. Early diagnosis and treatment of MPNs is essential to prevent recurrence of thrombotic events and may reduce mortality and morbidity related to thrombotic complications. (C) 2019 Sociedade Portuguesa de Cardiologia. Published by Elsevier Espana, S.L.U

A huge multilocular hydatid cyst with an unusual localization

WOS: 000367502600024PubMed ID: 26717232

Subclinical Left Ventricular Systolic Dysfunction in Patients with Coronary Artery Anomaly: A Speckle Tracking and Velocity Vector Imaging-Based Study

29th Turkish Cardiology Congress of the Turkish-Society-of-Cardiology (TSC) with International Participation -- OCT 26-29, 2013 -- Antalya, TURKEYWOS: 000329858400497…Turkish Soc Cardio

Evaluation of Carotid Intima- Media Thickness and Aortic Elasticity in Patients with Nondipper Hypertension

WOS: 000334864400024PubMed ID: 24219389BackgroundThe relationship between cardiovascular diseases and the diurnal blood pressure (BP) rhythm was researched in many studies. It has been demonstrated that the nondipping pattern has been associated with target organ damage and worsened cardiovascular outcomes. The aim of our study was to assess the relationship between aortic elasticity parameters and carotid intima-media thickness (CIMT) and diastolic dysfunction in terms of dipper and nondipper hypertension subtypes. MethodsA total of 60 hypertensive patients without known coronary heart disease were recruited to our study. All patients were classified as dipper or nondipper after ambulatory BP follow-up. Patients' left ventricular (LV) systolic and diastolic functions were assessed with transthoracic echocardiography. Ascending aorta diameters and CIMT were measured by ultrasonography and the elasticity parameters of aorta were calculated by using relevant formula. ResultsThere were no significant differences between the groups with respect to demographic, biochemical data, and cardiovascular risk factors. Aortic stiffness was significantly increased in nondippers, whereas aortic strain and distensibility were significantly decreased (P=0.005, P=0.005, and P=0.024, respectively). Carotid artery IMT was significantly increased in nondippers compared to dippers (P=0.013). A significant correlation was noted between CIMT and mean BP. No significant difference was detected between 2 groups in terms of LV hypertrophy and diastolic dysfunction. ConclusionIn our study, we showed that impairment of aortic elasticity parameters and increase in CIMT as a predictor of end organ damage were more often in the nondipper hypertensive patients

Ganglioneuroma of the neck: A case report

Objectives: An unusual left parapharyngeal ganglioneuroma case was discussed in the context of diagnostic difficulties, surgical tricks and Horner syndrome as a main surgical complication.Methods: The patient presented with a painless neck mass. Fine needle aspiration did not give any clue regarding diagnosis. The mass was removed totally by a challenging surgery.&nbsp;Results: Histopathology revealed ganglioneuroma. Horner syndrome occurred after surgery.Conclusion: Due to the scarcity of ganglioneuromas and the lack of specific signs and symptoms, it is often difficult to reach a definitive diagnosis prior to pathological examination. Ganglioneuromas should be considered in differential diagnosis of cervical neck masses located medial to main neurovascular structures. The patients should be warned of the possible complication of Horner syndrome.</p

Lobular breast cancer metastasis to uterus during adjuvant tamoxifen treatment: A case report and review of the literature.

Tamoxifen plays a critical role in the treatment of hormone receptor-positive breast cancer. Despite these great benefits against breast cancer, tamoxifen increases the risk of endometrial pathologies such as endometrial hyperplasia, polyp, and neoplasms because of agonistic effect on endometrial tissues. Therefore, gynecologic follow-up should be carried out during tamoxifen treatment. Uterine tumors are frequently detected as the result of presentation with abnormal uterine bleeding. In addition, genital tract's metastases from distant primary tumors can present with abnormal uterine bleeding. Therefore, it is important to determine whether the uterine mass is metastatic or primary because different treatment modalities are used for them. In this context, breast carcinomas are the most frequent metastatic tumors, particularly invasive lobular carcinoma. Here, we report an invasive lobular carcinoma case that presented with abnormal uterine bleeding while receiving tamoxifen therapy and has metastasize in the uterus

Unexpected diagnosis in a liver donor candidate

WOS: 000388798200013PubMed ID: 27865675

A case of membranous glomerulopathy associated with lung cancer and review of the literature.

Membraneous nephropathy (MN) is the most commonly occurring nephrotic syndrome in adults as well as the most common paraneoplastic nephropathy associated with solid tumors, and it is mostly associated with gastrointestinal system and lung carcinomas. Accurate diagnosis is important as the treatment of paraneoplastic glomerulonephritis is very varied from that of idiopathic ones. In the current report, a case of a patient that was referred with proteinuria and edema and was diagnosed with lung cancer, and responded markedly to treatment of malignancy, with improvement of MN, is presented. Active cancer is present in all patients with paraneoplastic MN. In numerous patients, the paraneoplastic MN and cancer diagnoses are made within one year of each other. The treatment of paraneoplastic syndromes is usually associated with the treatment of primary malignancy. There are conflicting data on which treatment modality is more suitable. In conclusion, further studies are required in order to determine the actual incidence of cancer in patients with nephropathy, explain the physiopathological association between cancer and nephropathy and to determine the most suitable treatment approaches