102 research outputs found

    Embeddings of Product Graphs Where One Factor is a Hypercube

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    Voltage graph theory can be used to describe embeddings of product graphs if one factor is a Cayley graph. We use voltage graphs to explore embeddings of various products where one factor is a hypercube, describing some minimal and symmetrical embeddings. We then define a graph product, the weak symmetric difference, and illustrate a voltage graph construction useful for obtaining an embedding of the weak symmetric difference of an arbitrary graph with a hypercube

    Congenital leukemia presenting as fever in a neonate

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    Background Emergency department workup of pediatric fever typically focuses on ruling out serious bacterial infection, but other disease processes can cause fever. Congenital leukemia is a rare but important cause of fever in neonates. We review the presentation, pathophysiology, and potential complications of congenital leukemia presenting to the emergency department as pediatric fever. Case Report We report a case of a 4-week-old infant brought to the emergency department for fever and “not acting normally.” Complete blood count demonstrated hyperleukocytosis. Subsequent bone marrow biopsy and flow cytometry confirmed the diagnosis of congenital leukemia. The extreme elevation of the patient's white blood cell count put her at high risk for complications, necessitating aggressive treatment, close monitoring, and appropriate consultation for comprehensive care. Why Should an Emergency Physician Be Aware of This Congenital leukemia is a rare but serious cause of neonatal fever. While the workup for fever without a source in young pediatric patients primarily focuses on ruling out serious bacterial illness, emergency physicians must be familiar with other potentially life-threatening causes of this complaint

    Enough Is Enough : Ten Years of Carcieri v . Salazar

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    Ten years ago, the United States Supreme Court issued its watershed decision in Carcieri v. Salazar, landing a gut punch to Indian country. Through that decision, the Supreme Court upended decades of Department of the Interior regulations, policy, and practice related to the eligibility of all federally recognized tribes for the restoration of tribal homelands through the Indian Reorganization Act (IRA) of 1934. The Court held that tribes must demonstrate that they were “under federal jurisdiction” in 1934 to qualify for land into trust under the first definition of “Indian” in the IRA. Carcieri has impacted all tribes by upending the land-into-trust process and requiring tribes (and Interior) to spend scant resources to establish statutory authority for trust land acquisitions, a burdensome task that had previously been straight forward. In addition, Carcieri has complicated, if not prevented altogether, trust acquisition for tribes who face difficulty in making the requisite jurisdictional showing. This Article provides the first comprehensive analysis of the last ten years of Indian law and policy that have unfurled from the Supreme Court’s decision. It describes how Carcieri has been weaponized by states, local governments, citizens’ groups, individuals, corporations, and even other tribes, to challenge the exercise of tribal sovereignty through the acquisition of tribal lands, and, at times, the very existence of Indian tribes.This Article details the litigation that has since ballooned, illustrating the dangerous scope creep of Carcieri, while categorizing and evaluating the underlying claims. It also looks to the future, and concludes that, while unlikely, a universal, clean congressional fix is the only real solution. The last ten years of litigation, hearings, and never-ending debate demonstrate that Carcieri is not a constructive or appropriate framework for resolving larger policy questions about the land-into-trust process. Finally, the Article ends by providing practice tips for tribes navigating the current Carcieri landscape

    Testing for Transition

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    This article describes multiple stages of usability testing that were conducted before and after a large research library’s transition to a new platform for its research guides. A large interdepartmental team sought user feedback on the design, content, and organization of the guide homepage, as well as on individual subject guides. This information was collected using an open-card-sort study, two face-to-face, think-aloud testing protocols, and an online survey. Significant findings include that users need clear directions and titles that incorporate familiar terminology, do not readily understand the purpose of guides, and are easily overwhelmed by excess information, and that many of librarians’ assumptions about the use of library resources may be mistaken. This study will be of value to other library workers seeking insight into user needs and behaviors around online resources

    Beyond the Paleolithic prescription: incorporating diversity and flexibility in the study of human diet evolution

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    Evolutionary paradigms of human health and nutrition center on the evolutionary discordance or “mismatch” model whereby human bodies, reflecting adaptations established in the Paleolithic era, are ill-suited to modern industrialized diets resulting in rapidly increasing rates of chronic metabolic disease. Whereas this model remains useful, we argue that its utility in explaining the evolution of human dietary tendencies is limited. The assumption that human diets are mismatched to our evolved biology implies that they are instinctual or genetically determined and rooted in the Paleolithic. We review current research indicating that human eating habits are primarily learned through behavioral, social and physiological mechanisms starting in utero and extending throughout the life course. Those adaptations that appear to be strongly genetic likely reflect Neolithic, rather than Paleolithic, adaptations and are significantly influenced by human niche-constructing behavior. Incorporating a broader understanding of the evolved mechanisms by which humans learn and imprint eating habits and the reciprocal effects of those habits on physiology would provide useful tools for structuring more lasting nutrition interventions

    Climate change: Helping nature survive the human response

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    Climate change poses profound, direct, and well-documented threats to biodiversity. A significant fraction of Earth\u27s species is at risk of extinction due to changing precipitation and temperature regimes, rising and acidifying oceans, and other factors. There is also growing awareness of the diversity and magnitude of responses, both proactive and reactive, that people will undertake as lives and livelihoods are affected by climate change. Yet to date few studies have examined the relationship between these two powerful forces. The natural systems upon which people depend, already under direct assault from climate change, are further threatened by how we respond to climate change. Human history and recent studies suggest that our actions to cope with climate change (adaptation) or lessen its rate and magnitude (mitigation) could have impacts that match-and even exceed-the direct effects of climate change on ecosystems. If we are to successfully conserve biodiversity and maintain ecosystem services in a warming world, considerable effort is needed to predict and reduce the indirect risks created by climate change. ©2010 Wiley Periodicals, Inc.
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