414 research outputs found
Anharmonic properties of double giant dipole resonance
A systematic microscopic study of the anharmonic properties of the double
giant dipole resonance (DGDR) has been carried out, for the first time, for
nuclei with mass number spanning the whole mass table. It is concluded that
the corrections of the energy centroid of the and
components of the DGDR from its harmonic limit are negative, have a value of
the order of few hundred keV and follow an dependence.Comment: 4 pages, 2 figure
Characterization of Spatiooral Cardiac Action Potential Variability at Baseline and under ß-Adrenergic Stimulation by Combined Unscented Kalman Filter and Double Greedy Dimension Reduction
Objective: Elevated spatiooral variability of human ventricular repolarization has been related to increased risk for ventricular arrhythmias and sudden cardiac death, particularly under ß-adrenergic stimulation (ß-AS). This work presents a methodology for theoretical characterization of temporal and spatial repolarization variability at baseline conditions and in response to ß-AS. For any measured voltage trace, the proposed methodology estimates the parameters and state variables of an underlying human ventricular action potential (AP) model by combining Double Greedy Dimension Reduction (DGDR) with automatic selection of biomarkers and the Unscented Kalman Filter (UKF). Such theoretical characterization can facilitate subsequent characterization of underlying variability mechanisms.
Material and Methods: Given an AP trace, initial estimates for the ionic conductances in a stochastic version of the baseline human ventricular O'Hara et al. model were obtained by DGDR. Those estimates served to initialize and update model parameter estimates by the UKF method based on formulation of an associated nonlinear state-space representation and joint estimation of model parameters and state variables. Similarly, ß-AS-induced phosphorylation levels of cellular substrates were estimated by the DGDR-UKF methodology. Performance was tested by building an experimentally-calibrated population of virtual cells, from which synthetic AP traces were generated for baseline and ß-AS conditions.
Results: The combined DGDR-UKF methodology led to 25% reduction in the error associated with estimation of ionic current conductances at baseline conditions and phosphorylation levels under ß-AS with respect to individual DGDR and UKF methods. This improvement was not at the expense of higher computational load, which was diminished by 90% with respect to the individual UKF method. Both temporal and spatial AP variability of repolarization were accurately characterized by the DGDR-UKF methodology. Conclusions: A combined DGDR-UKF methodology is proposed for parameter and state variable estimation of human ventricular cell models from available AP traces at baseline and under ß-AS. This methodology improves the estimation performance and reduces the convergence time with respect to individual DGDR and UKF methods and renders a suitable approach for computational characterization of spatiooral repolarization variability to be used for ascertainment of variability mechanisms and its relation to arrhythmogenesis
Lowest-lying Tetra-Quark Hadrons in Anisotropic Lattice QCD
We present a detailed study of lowest-lying hadrons in
quenched improved anisotropic lattice QCD. Using the and
diquark-antidiquark local and smeared operators, we attempt to isolate the
signal for and states in two flavour
QCD. In the chiral limit of light-quark mass region, the lowest scalar
state is found to have a mass, MeV, which is slightly
lower than the experimentally observed . The results from our
variational analysis do not indicate a signature of a tetraquark resonance in
I=1 and I=2 channels. After the chiral extrapolation the lowest
state is found to have a mass, MeV. We analysed the
static potential extracted form a tetraquark Wilson loop and illustrated
the behaviour of the state as a bound state, unbinding at some critical
diquark separation. From our analysis we conclude that scalar system
appears as a two-pion scattering state and that there is no spatially-localised
state in the light-quark mass region.Comment: 9 pages, 10 figure
Calculation of the properties of the rotational bands of Gd
We reexamine the long-standing problem of the microscopic derivation of a
particle-core coupling model. We base our research on the Klein-Kerman
approach, as amended by D\"onau and Frauendorf. We describe the formalism to
calculate energy spectra and transition strengths in some detail. We apply our
formalism to the rotational nuclei Gd, where recent experimental
data requires an explanation. We find no clear evidence of a need for Coriolis
attenuation.Comment: 27 pages, 13 uuencoded postscript figures. Uses epsf.st
Correlation energy contribution to nuclear masses
The ground state correlation energies associated with collective surface and
pairing vibrations are calculated for Pb- and Ca-isotopes. It is shown that
this contribution, when added to those predicted by one of the most accurate
modern nuclear mass formula (HFBCS MSk7 mass formula), reduces the associated
rms error by an important factor, making mean field theory, once its time
dependence is taken into account, a quantitative predictive tool for nuclear
masses.Comment: 4 pages, 2 figures, RevTeX
Parametrization of the octupole degrees of freedom
A simple parametrization for the octupole collective variables is proposed
and the symmetries of the wave functions are discussed in terms of the
solutions corresponding to the vibrational limit. [PACS: 21.60Ev, 21.60.Fw,
21.10.Re]Comment: 14 page
Nanostructured gadolinium-doped ceria microsphere synthesis from ion exchange resin: Multi-scale in-situ studies of solid solution formation
Nuclear Scissors Mode with Pairing
The coupled dynamics of the scissors mode and the isovector giant quadrupole
resonance are studied using a generalized Wigner function moments method taking
into account pair correlations. Equations of motion for angular momentum,
quadrupole moment and other relevant collective variables are derived on the
basis of the time dependent Hartree-Fock-Bogoliubov equations. Analytical
expressions for energy centroids and transitions probabilities are found for
the harmonic oscillator model with the quadrupole-quadrupole residual
interaction and monopole pairing force. Deformation dependences of energies and
values are correctly reproduced. The inclusion of pair correlations
leads to a drastic improvement in the description of qualitative and
quantitative characteristics of the scissors mode.Comment: 36 pages, 5 figures, the results of calculation by another method and
the section concerning currents are adde
Quark-hadron-duality in the charmonium and upsilon system
In this work we discuss the practical and conceptual issues related to
quark-hadron-duality in heavy-heavy systems. Recent measurements in the
charmonium region allow a direct test of quark-hadron-duality. We present a
formula for non-resonant background production in e^+ e^- \to D{\bar D} and
extract the resonance parameters of the \psi(3S)-\psi(6S). The obtained results
are used to investigate the upsilon energy range.Comment: 21 pages, 3 figures, references adde
SU(3) realization of the rigid asymmetric rotor within the IBM
It is shown that the spectrum of the asymmetric rotor can be realized quantum
mechanically in terms of a system of interacting bosons. This is achieved in
the SU(3) limit of the interacting boson model by considering higher-order
interactions between the bosons. The spectrum corresponds to that of a rigid
asymmetric rotor in the limit of infinite boson number.Comment: 9 pages, 2 figures, LaTeX, epsfi
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