392 research outputs found

    Transformations urbaines et Migrations dans les villes espagnoles

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    Les 8 et 9 dĂ©cembre 2011, deux journĂ©es d’étude portant sur le thĂšme des « transformations urbaines et migrations dans les villes espagnoles » se sont dĂ©roulĂ©es dans les locaux de la MSHS de l’UniversitĂ© de Poitiers. OrganisĂ©e par NaĂŻk Miret (Migrinter), cette rencontre a rassemblĂ© pour la quatriĂšme fois consĂ©cutive des chercheurs de plusieurs disciplines. Au travers de cas de villes espagnoles marquĂ©es par l’arrivĂ©e massive de migrants internationaux depuis la dĂ©cennie 1990, les intervenants..

    Le recrutement et la fidélisation des bénévoles retraités par les associations

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    National audienceEn raison du temps libre engendrĂ© par l’arrĂȘt de l’activitĂ© professionnelle, les retraitĂ©s deviennent une cible trĂšs convoitĂ©e par les associations Ă  la recherche de bĂ©nĂ©voles. Cependant, ils sont souvent considĂ©rĂ©s comme un segment homogĂšne, d’oĂč des difficultĂ©s de recrutement et de fidĂ©lisation par les associations. Pour y remĂ©dier, cet article propose une typologie de bĂ©nĂ©voles retraitĂ©s sur la base de leurs motivations et de caractĂ©ristiques psychosociales liĂ©es au vieillissement. Cinq profils se dĂ©gagent : les hĂ©donistes, les coupables, les affectifs, les soucieux de postĂ©ritĂ©, les ambitieux. Reste aux associations Ă  cibler un ou plusieurs profils selon la fonction Ă  pourvoir et Ă  adapter leurs campagnes de communication en consĂ©quence

    Hox genes define distinct progenitor sub-domains within the second heart field

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    AbstractMuch of the heart, including the atria, right ventricle and outflow tract (OFT) is derived from a progenitor cell population termed the second heart field (SHF) that contributes progressively to the embryonic heart during cardiac looping. Several studies have revealed anterior-posterior patterning of the SHF, since the anterior region (anterior heart field) contributes to right ventricular and OFT myocardium whereas the posterior region gives rise to the atria. We have previously shown that Retinoic Acid (RA) signal participates to this patterning. We now show that Hoxb1, Hoxa1, and Hoxa3, as downstream RA targets, are expressed in distinct sub-domains within the SHF. Our genetic lineage tracing analysis revealed that Hoxb1, Hoxa1 and Hoxa3-expressing cardiac progenitor cells contribute to both atria and the inferior wall of the OFT, which subsequently gives rise to myocardium at the base of pulmonary trunk. By contrast to Hoxb1Cre, the contribution of Hoxa1-enhIII-Cre and Hoxa3Cre-labeled cells is restricted to the distal regions of the OFT suggesting that proximo-distal patterning of the OFT is related to SHF sub-domains characterized by combinatorial Hox genes expression. Manipulation of RA signaling pathways showed that RA is required for the correct deployment of Hox-expressing SHF cells. This report provides new insights into the regulatory gene network in SHF cells contributing to the atria and sub-pulmonary myocardium

    Effect of the deposition route on the microstructure of plasma-sprayed hydroxyapatite coatings

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    Plasma-spray (PS) is the most common technique used to cover orthopaedic titanium-based implant surfaces with hydroxyapatite (HA - Ca10(PO4)6OH2). The objective of the current work was to explore the influence of the precursor nature and characteristics (mainly powder size, Ca/P ratio, and density) on the morphology and the microstructure of HA coatings, deposited either by conventional atmospheric plasma spray (APS) or by rf-suspension plasma spray (rf-SPS). Two powders with different size distribution, density and shape were sprayed with same operating APS conditions. In parallel two water-based suspensions with distinct particle size and chemistry (Ca/P ratio) were implemented in rf-SPS. The morphology of both APS and rf-SPS coatings observed by SEM exhibits micro and sub-micro sized structures respectively, with similar porosity and thickness. The difference in precursor particle size does not affect the coating structure in rf-SPS, unlike in APS conditions. Superimposition of topography and phases maps performed from profilometry and Raman cartographies showed no direct correlation between the surface profile and composition. But such analysis highlighted the heterogeneity of the phases composing the coating surface, opening the possibility of a better understanding of biological behaviour

    Dynamical modeling of bi-layer Aluminium adhesive tape for laser shock applications

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    The presented work covers the response of Aluminium tape (Al tape) under high strain rate of deformation (order of 106s−1) using laser shock. High power laser (J) with a short pulse duration (ns) is used to create laser shock within the water confinement regime on two Al tape configurations in order to apply low and high pressure (order of MPa and GPa). Al tape has been modeled using Johnson-Cook (J-C) material model for the Al layer, and Steinberg–Cochran–Guinan (SCG) material model (elastic with pressure dependence) for the adhesive layer, both material models are coupled with GrĂŒneisen equation of state. The Al tape model has been validated by comparing the simulated Back Face Velocity (BFV) of the target with the measured one by the Velocity Interferometer System for Any Reflector (VISAR). In addition, the validated material model is used to conduct the sensitivity studies about the transmitted pressure depending on the acoustical impedance of the target and adhesive thickness. Moreover, location and magnitude of maximum tensile stress within the target are calculated in function of the adhesive thickness of the Al tape. Finally, it has been proved that using one laser beam configuration, maximum tensile zone could appears close to the front face by increasing the adhesive thickness

    Laser induced plasma characterization in direct and water confined regimes: new advances in experimental studies and numerical modelling

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    Optimization of the laser shock peening (LSP) and LASer Adhesion Test (LASAT) processes requires control of the laser-induced target's loading. Improvements to optical and laser technologies allow plasma characterization to be performed with greater precision than 20 years ago. Consequently, the processes involved during laser-matter interactions can be better understood. For the purposes of this paper, a self-consistent model of plasma pressure versus time is required. The current approach is called the inverse method, since it is adjusted until the simulated free surface velocity (FSV) corresponds to the experimental velocity. Thus, it is not possible to predict the behavior of the target under shock without having done the experiments. For the first time, experimental data collected in different labs with the most up-to-date laser parameters are used to validate a self-consistent model for temporal pressure-profile calculation. In addition, the parameters characterizing the plasma (temperature, thickness and duration) are obtained from the ESTHER numerical code, together with the amount of ablated matter. Finally, analytic fits are presented that can reproduce any pressure-temporal profiles in the following domains of validity: Intensities, I, ranging from 10 to 500 GW cm-2 and pulse durations, T pul, between 5 and 40 ns for the direct-illumination regime at 1053 nm, I ranging from 1 to 6 GW cm-2 and T pul between 10 to 40 ns in the water-confined regime at 1053 nm, and I from 1 to 10 GW cm-2 and T pul between 7 and 20 ns in the water-confined regime at 532 nm. These temporal pressure profiles can then be used to predict the aluminum target's behavior under laser shock using mechanical simulation software

    Anterolateral Ligament Reconstruction Does Not Delay Functional Recovery, Rehabilitation, and Return to Sport After Anterior Cruciate Ligament Reconstruction: A Matched-Pair Analysis From the SANTI (Scientific ACL Network International) Study Group.

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    PurposeTo determine whether the addition of an anterolateral ligament reconstruction (ALLR) resulted in delayed functional recovery (based on the Knee Santy Athletic Return to Sport [K-STARTS] score) at 6 months after anterior cruciate ligament reconstruction (ACLR).MethodsA retrospective analysis of prospectively collected data from consecutive patients who underwent an ACLR between September 2017 and December 2020 was conducted. Patients who received an isolated hamstring autograft (isolated ACLR group) were propensity matched in a 1:1 ratio to patients who received a hamstring autograft ACLR combined with an ALLR (ACLR-ALLR group). Outcome measures included the Tegner Activity Scale and the K-STARTS test-a validated composite return-to-sports test (including the Anterior Cruciate Ligament-Return to Sport After Injury scale, Qualitative Assessment of Single-Leg Landing tool, limb symmetry index, and ability to change direction using the Modified Illinois Change of Direction Test).ResultsThe study included 111 matched pairs. At 6 months postoperatively, there were no significant differences between groups in the overall K-STARTS score (65.4 for isolated ACLR vs 61.2 for ACLR-ALLR, P = .087) or the Tegner Activity Scale score (3.7 for isolated ACLR vs 3.8 for ACLR-ALLR, P = .45). In addition, an evaluation of the subscales of the K-STARTS score revealed no disadvantage across the domains of neuromuscular control, limb symmetry index, agility, or psychological readiness to return to sport when an ALLR was performed.ConclusionsThe addition of ALLR at the time of ACLR does not delay functional recovery. Specifically, at 6 months postoperatively, there was no disadvantage in patients undergoing ALLR-ACLR, when compared with those undergoing isolated ACLR, with respect to neuromuscular control, limb symmetry indices (hop tests), agility, or psychological readiness to return to sport.Level of evidenceLevel III, retrospective comparative study
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