Effective Vector Data Transmission and Visualization Using HTML5

In this paper we evaluate the potential of the next major revision of HTML (Hypertext Markup Language), that is HTML5, to provide an effective platform for the transmission and visualization of vector based geographical data. Relative to the current version of HTML, HTML 4.01, HTML5 offers an improved platform to perform these tasks through greater interoperability with existing technologies and the introduction of many new API’s. Visualization of vector data can be achieved using the new methods of inline-SVG and the Canvas API. An analysis of the pros and cons of each method is presented. HTML5 introduces a novel WebSocket API which defines a full-duplex communication channel between client and server. This provides improved data communication both in terms of bandwidth utilization and network latency relative to existing push technologies. To demonstrate the effectiveness of HTML5 for vector data delivery a novel selective progressive transmission methodology is implemented using the WebSocket and Canvas API’s

The added value of simultaneous palpation during scrotal ultrasound

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Hyperhidrosis treatment with bornaprine in the acute phase of spinal cord-injured patients

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Multiple Sclerosis State of the Art (SMART): A Qualitative and Quantitative Analysis of Therapy’s Adherence, Hospital Reliability’s Perception, and Services Provided Quality

The purpose of this study was to assess the adherence to therapy in patients with relapsing remitting multiple sclerosis (RR-MS) and to analyze the possible influence of factors such as hospital care and patients socioeconomic status. Two hundred eighty-five patients with RR-MS according to Mc Donald’s criteria and naïve disease-modifying drugs (DMDs) naïve were enrolled. Two self-administered questionnaires addressing the management of patients at therapy prescription and the personal perception of the daily life changes caused by DMDs were administered at months 3 and 12. Full adherence, considered as correct use of the therapy prescribed, was observed in a very high percentage of subjects (97.3% and 93.9% at 3 and 12 months). The main cause for reduced adherence was single dose forgetfulness, followed by anxiety, pain at the injection site, and tiredness of “doing all injections.” Nurses and neurologists of MS Center were identified as the major resource in coping with the disease at 3 and 12 months by patients. The neurologist was the health professional involved in MS management in 95% of cases and the nurse appeared to play a central role in patient training and drug administration management (50.3%)

Partial wave analysiss of pbar-p -> piminus-piplus, pizero-pizero, eta-eta and eta-etaprime

A partial wave analysis is presented of Crystal Barrel data on pbar-p -> pizero-pizero, eta-eta and eta-etaprime from 600 to 1940 MeV/c, combined with earlier data on d\sigma /d\Omega and P for pbar-p->piminus-piplus. The following s-channel I=0 resonances are identified: (i) J^{PC} = 5^{--} with mass and width (M,\Gamma) at (2295+-30,235^{+65}_{-40}) MeV, (ii) J^{PC} = 4^{++} at (2020+-12, 170+-15) MeV and (2300+-25, 270+-50) MeV, (iii) 3D3 JPC = 3^{--} at (1960+-15, 150+-25) MeV and (2210+-4$, 360+-55) MeV, and a 3G3 state at (2300 ^{+50}_{-80}, 340+-150) MeV, (iv) JPC = 2^{++} at (1910+-30, 260+-40) MeV, (2020+-30, 275+-35) MeV, (2230+-30, 245+-45) MeV, and (2300+-35, 290+-50) MeV, (v) JPC = 1^{--} at (2005+-40, 275+-75) MeV, and (2165+-40, 160 ^{+140}_{-70}) MeV, and (vi) JPC = 0^{++} at (2005+-30, 305+-50) MeV, (2105+-15, 200+-25) MeV, and (2320+-30, 175+-45) MeV. In addition, there is a less well defined 6^{++} resonance at 2485+-40 MeV, with Gamma = 410+-90 MeV. For every JP, almost all these resonances lie on well defined linear trajectories of mass squared v. excitation number. The slope is 1.10+-0.03 Gev^2 per excitation. The f_0(2105) has strong coupling to eta-\eta, but much weaker coupling to pizero-pizero. Its flavour mixing angle between q-qbar and s-sbar is (59-71.6)deg, i.e. dominant decays to s-sbar. Such decays and its strong production in pbar-p interactions strongly suggest exotic character.Comment: Makes available the combined fit to Crystal Barrel data on pbar-p -> 2-body final states. 29 pages, 11 figures. Typo corrected in version

Myostatin mediates abdominal aortic atherosclerosis progression by inducing vascular smooth muscle cell dysfunction and monocyte recruitment

Myostatin (Mstn) is a skeletal muscle growth inhibitor involved in metabolic disorders and heart fibrosis. In this study we sought to verify whether Mstn is also operative in atherosclerosis of abdominal aorta. In human specimens, Mstn expression was almost absent in normal vessels, became detectable in the media of non-progressive lesions and increased with the severity of the damage. In progressive atherosclerotic lesions, Mstn was present in the media, neointima, plaque shoulder and in infiltrating macrophages. Mstn co-localized with \uce\ub1-smooth muscle actin (\uce\ub1-SMA) staining and with some CD45+ cells, indicating Mstn expression in VSMCs and bloodstream-derived leukocytes. In vitro, Mstn was tested in VSMCs and monocytes. In A7r5 VSMCs, Mstn downregulated proliferation and Smoothelin mRNA, induced cytoskeletal rearrangement, increased migratory rate and MCP-1/CCR2 expression. In monocytes (THP-1 cells and human monocytes), Mstn acted as a chemoattractant and increased the MCP-1-dependent chemotaxis, F-actin, \uce\ub1-SMA, MCP-1 and CCR2 expression; in turn, MCP-1 increased Mstn mRNA. Mstn induced JNK phosphorylation both in VSMCs and monocytes. Our results indicate that Mstn is overexpressed in abdominal aortic wall deterioration, affects VSMCs and monocyte biology and sustains a chronic inflammatory milieu. These findings propose to consider Mstn as a new playmaker in atherosclerosis progression