16,219 research outputs found

    Care Management of Patients With Complex Health Care Needs

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    Explores how patients' complexity of healthcare needs, vulnerability, and age affect the cost and quality of their health care. Examines the potential for care management to improve quality of care and reduce costs, elements of success, and challenges

    Stable coronary syndromes: pathophysiology, diagnostic advances and therapeutic need

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    The diagnostic management of patients with angina pectoris typically centres on the detection of obstructive epicardial CAD, which aligns with evidence-based treatment options that include medical therapy and myocardial revascularisation. This clinical paradigm fails to account for the considerable proportion (approximately one-third) of patients with angina in whom obstructive CAD is excluded. This common scenario presents a diagnostic conundrum whereby angina occurs but there is no obstructive CAD (ischaemia and no obstructive coronary artery disease—INOCA). We review new insights into the pathophysiology of angina whereby myocardial ischaemia results from a deficient supply of oxygenated blood to the myocardium, due to various combinations of focal or diffuse epicardial disease (macrovascular), microvascular dysfunction or both. Macrovascular disease may be due to the presence of obstructive CAD secondary to atherosclerosis, or may be dynamic due to a functional disorder (eg, coronary artery spasm, myocardial bridging). Pathophysiology of coronary microvascular disease may involve anatomical abnormalities resulting in increased coronary resistance, or functional abnormalities resulting in abnormal vasomotor tone. We consider novel clinical diagnostic techniques enabling new insights into the causes of angina and appraise the need for improved therapeutic options for patients with INOCA. We conclude that the taxonomy of stable CAD could improve to better reflect the heterogeneous pathophysiology of the coronary circulation. We propose the term ‘stable coronary syndromes’ (SCS), which aligns with the well-established terminology for ‘acute coronary syndromes’. SCS subtends a clinically relevant classification that more fully encompasses the different diseases of the epicardial and microvascular coronary circulation

    Anomalous Hall effect in the Co-based Heusler compounds Co2_{2}FeSi and Co2_{2}FeAl

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    The anomalous Hall effect (AHE) in the Heusler compounds Co2_{2}FeSi and Co2_{2}FeAl is studied in dependence of the annealing temperature to achieve a general comprehension of its origin. We have demonstrated that the crystal quality affected by annealing processes is a significant control parameter to tune the electrical resistivity ρxx\rho_{xx} as well as the anomalous Hall resistivity ρahe\rho_{ahe}. Analyzing the scaling behavior of ρahe\rho_{ahe} in terms of ρxx\rho_{xx} points to a temperature-dependent skew scattering as the dominant mechanism in both Heusler compounds

    The Christian Future and the Fate of Earth

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    "[This book] may be the best guide yet to the work of Thomas Berry. It is as though these essays embody the bonding force he calls the Great Compassionate Curve of the universe."--Catherine Keller  "A highly readable gem."--Catholic Library World  "Inspiring, often lyrical."--St. Anthony Messenger  Like no other religious thinker, Thomas Berry has been a prophetic voice regarding Earth's destruction and the urgent need for human response from the Christian community. This book collects Berry's signature views on the interrelatedness of both Earth's future and the Christian future. He ponders why Christians have been late in coming to the issue of the environment. He reflects insightfully on how the environment must be seen as a religious issue, not simply a scientific or economic problem. In powerful and poetic language Berry presents a compelling vision of the sacredness of the universe and the interrelatedness of the Earth community. Drawing on Thomas Aquinas and Teilhard de Chardin he brings the Christian tradition into a cosmology of care for the whole of creation

    Explaining the Persistence of the “Ample Alternative Channels” Test

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    Orbital Spacecraft Consumables Resupply System

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    This paper describes the work completed on the Orbital Spacecraft Consumables Resupply System (OSCRS) for the Johnson Space Center (JSC) under Contract NAS9-17586. The study objective was to provide a concept to NASA for supplying earth storable liquids and gases to a variety of orbiting vehicles, including Space Station, OMV and other satellites in orbits compatible with Shuttle resupply. The design developed by the Fairchild Space Company was driven by life cycle cost. The aesign is based on a cylindrical propellant tank optimized for transporting liquids in the Orbiter bay. The tank is polar mounted with the attachment fittings configured as Orbiter sill trunnions. The pressurant tanks provide support between the sill and keel fittings. Two potential spacecraft interface mechanisms were investigated. Continuing OSCRS effort will be directed toward further standardization studies, adapting the design to the Space Station Servicing Bay and investigating the possibilities of using ELV launchers

    Pre-Test Assessment

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    Pre-tests are a non-graded assessment tool used to determine pre-existing subject knowledge.  Typically pre-tests are administered prior to a course to determine knowledge baseline, but here they are used to test students prior to topical material coverage throughout the course.  While counterintuitive, the pre-tests cover material the student is not expected to know, but serve as a motivational tool and a ‘road map’ for the students, resulting in improved course performance.
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