571 research outputs found
The Photometric Period of the Cataclysmic Variable HV Andromedae
We present four nights of time-resolved photometry of the cataclysmic
variable star HV And. Our time series analysis has revealed a prominent period
at 3.368 +/- 0.060 hours, as well as some low frequency power. We interpret
this signal, from saw-tooth waves in the light curve, as evidence of superhumps
in HV And.Comment: 7 pages, 3 figures; accepted for publication in New Astronom
Cyanobacterial Toxins as Allelochemicals with Potential Applications as Algaecides, Herbicides and Insecticides
Cyanobacteria (“blue-green algae”) from marine and freshwater habitats are known to produce a diverse array of toxic or otherwise bioactive metabolites. However, the functional role of the vast majority of these compounds, particularly in terms of the physiology and ecology of the cyanobacteria that produce them, remains largely unknown. A limited number of studies have suggested that some of the compounds may have ecological roles as allelochemicals, specifically including compounds that may inhibit competing sympatric macrophytes, algae and microbes. These allelochemicals may also play a role in defense against potential predators and grazers, particularly aquatic invertebrates and their larvae. This review will discuss the existing evidence for the allelochemical roles of cyanobacterial toxins, as well as the potential for development and application of these compounds as algaecides, herbicides and insecticides, and specifically present relevant results from investigations into toxins of cyanobacteria from the Florida Everglades and associated waterways
Stratigraphic and material interpretations of site evidence : investigations towards the nature of archaeological deposits
This dissertation addresses the failure in common practice to fully integrate different parts of the archaeological record systematically, thus leading to a breakdown between excavation theory and practice. The relationship between deposit and assemblage, and thereby the use of deposit status designation is examined. A more accurate definition of status is adopted, overcoming the conceptual inadequacy linking find to deposit. The analysis of status is based on the following basic assumptions: firstly, that status is the relationship between the find and the context; secondly, that this relationship is based upon information on the function, chronology and spatial characteristics of the finds and contexts. With the concept of deposit status established, this thesis presents a method that ates all the relevant elements of the archaeological record that enable an understanding of deposit signatures; deposits and assemblages. Deposit types are examined, checking the relationships between basic physical descriptions and interpreted function. Assemblage data for ceramics and faunal remains are integrated based upon quantification that reflects their separate formafion histories. The resulting deposit signatures provide a platform for new and interesting means of reating site narrative. The new narratives reflect developments and changes in eposit formation, and ultimately, the landuse history of a site. This thesis demonstrates that the integration of finds and site data allows for more fruitful interpretation of excavation data. This approach helps to match site details with specific research agendas in both academic and commercial contexts, and can help achieve the maximum potential for research output
Mosquito Larvicides from Cyanobacteria
Cyanobacteria (blue-green algae) produce a diverse array of toxic or otherwise bioactive metabolites. These allelochemicals may also play a role in defense against potential predators and grazers, particularly aquatic invertebrates and their larvae, including mosquitoes. Compounds derived from cyanobacteria collected from the Florida Everglades and other Florida waterways were investigated as insecticides against the mosquito Aedes aegypti, a vector of dengue and yellow fever. Screening of cyanobacterial biomass revealed several strains that exhibited mosquito larvicidal activity. Guided via bioassay guided fractionation, a non-polar compound from Leptolyngbya sp. 21-9-3 was found to be the most active component. Characterization revealed the prospective compound to be a monounsaturated fatty acid with the molecular formula C16H30O2. This is the first evidence of mosquito larvicidal activity for this particular fatty acid. With larvicidal becoming more prevalent, fatty acids should be explored for future mosquito control strategies
Cyclin D1 and p16 expression in recurrent nasopharyngeal carcinoma
Abstract
Background
Cyclin D1 and p16 are involved in the regulation of G1 checkpoint and may play an important role in the tumorigenesis of nasopharyngeal carcinoma (NPC). Previous studies have examined the level of expression of cyclin D1 and p16 in primary untreated NPC but no such information is available for recurrent NPC. We set out in this study to examine the expression level of cyclin D1 and p16 in recurrent NPC that have failed previous treatment with radiation +/- chemotherapy.
Patients and methods
A total of 42 patients underwent salvage nasopharyngectomy from 1984 to 2001 for recurrent NPC after treatment failure with radiation +/- chemotherapy. Twenty-seven pathologic specimens were available for immunohistochemical study using antibodies against cyclin D1 and p16.
Results
Positive expression of cyclin D1 was observed in 7 of 27 recurrent NPC specimens (26%) while positive p16 expression was seen in only 1 of 27 recurrent NPC (4%).
Conclusion
While the level of expression of cyclin D1 in recurrent NPC was similar to that of previously untreated head and neck cancer, the level of p16 expression in recurrent NPC samples was much lower than that reported for previously untreated cancer. The finding that almost all (96%) of the recurrent NPC lack expression of p16 suggested that loss of p16 may confer a survival advantage by making cancer cells more resistant to conventional treatment with radiation +/- chemotherapy. Further research is warranted to investigate the clinical use of p16 both as a prognostic marker and as a potential therapeutic target
OH-bearing planar defects in olivine produced by the breakdown of Ti-rich humite minerals from Dabie Shan (China)
The partial breakdown of Ti-chondrodite and Ti-clinohumite during exhumation from ultra-high pressure to amphibolite facies conditions in garnet-pyroxenites from Dabie Shan (China) produces coronas of olivine coexisting with ilmenite blebs. Fourier transform infrared (FTIR) spectra of this newly formed olivine exhibit absorption bands in the hydroxyl-stretching region. Two intense peaks were observed at 3,564 and 3,394 cm-1, identical in energy to peaks in Ti-clinohumite. Transmission electron microscopy (TEM) of the same olivine domains revealed the presence of a complex (001) planar intergrowth. These interlayers have a 1.35 nm repeat distance, which is characteristic of clinohumite. Such interlayers are also enriched in Ti with respect to the adjacent olivine as shown by energy dispersive spectrometry. The combined evidence from FTIR spectroscopy and TEM indicates that OH is incorporated along Ti-clinohumite planar defects. This study provides evidence that the nominally anhydrous phase olivine may contain OH as a humite-type defect beyond the breakdown of the hydrous humite minerals and confirms earlier suggestions that Ti plays a key role in OH incorporation in mantle olivine. We suggest that olivine containing Ti-clinohumite defects is an important phase for water transport in subduction zones and for the storage of water in cold subcontinental mantle. However, these defects are unlikely to be stable in hotter parts of the oceanic mantle such as where basaltic magmas are generated
The Photometric Period and Variability of the Cataclysmic Variable V849 Herculis (PG 1633+115)
We report time-resolved photometry of the cataclysmic variable V849 Her, and
measure a period of 0.1414 \pm 0.0030 days (3.394 \pm 0.072 hours). We also
present photometry taken over several weeks in 2010 and 2011, as well as light
curves from 1995 to 2011 by the American Association of Variable Star
Observers. The spectra, absolute magnitude derived from infrared magnitudes,
and variability all suggest that V849 Her is a nova-like variable. The shallow
(0.5-magnitude) low states we observe resemble the erratic low states of the VY
Sculptoris stars, although they may recur quasi-periodically over an average
cycle of 12.462 \pm 0.074 days.Comment: 18 pages, 9 figures, accepted for publication in New Astronom
Overview of Boundary Layer Transition Research in Support of Orbiter Return To Flight
A predictive tool for estimating the onset of boundary layer transition resulting from damage to and/or repair of the thermal protection system was developed in support of Shuttle Return to Flight. The boundary layer transition tool is part of a suite of tools that analyze the aerothermodynamic environment to the local thermal protection system to allow informed disposition of damage for making recommendations to fly as is or to repair. Using mission specific trajectory information and details of each damage site or repair, the expected time (and thus Mach number) at transition onset is predicted to help define the aerothermodynamic environment to use in the subsequent thermal and stress analysis of the local thermal protection system and structure. The boundary layer transition criteria utilized for the tool was developed from ground-based measurements to account for the effect of both protuberances and cavities and has been calibrated against select flight data. Computed local boundary layer edge conditions were used to correlate the results, specifically the momentum thickness Reynolds number over the edge Mach number and the boundary layer thickness. For the initial Return to Flight mission, STS-114, empirical curve coefficients of 27, 100, and 900 were selected to predict transition onset for protuberances based on height, and cavities based on depth and length, respectively
Pediatric Plastic Bronchitis: Case Report and Retrospective Comparative Analysis of Epidemiology and Pathology
Plastic bronchitis (PB) is a pathologic condition in which airway casts develop in the tracheobronchial tree causing airway obstruction. There is no standard treatment strategy for this uncommon condition. We report an index patient treated using an emerging multimodal strategy of directly instilled and inhaled tissue plasminogen activator (t-PA) as well as 13 other cases of PB at our institution between 2000 and 2012. The majority of cases (n = 8) occurred in patients with congenital heart disease. Clinical presentations, treatments used, histopathology of the casts, and patient outcomes are reviewed. Further discussion is focused on the epidemiology of plastic bronchitis and a systematic approach to the histologic classification of casts. Comorbid conditions identified in this study included congenital heart disease (8), pneumonia (3), and asthma (2). Our institutional prevalence rate was 6.8 per 100,000 patients, and our case fatality rate was 7%
Helicity, polarization, and Riemann-Silberstein vortices
Riemann-Silberstein (RS) vortices have been defined as surfaces in spacetime
where the complex form of a free electromagnetic field given by F=E+iB is null
(F.F=0), and they can indeed be interpreted as the collective history swept out
by moving vortex lines of the field. Formally, the nullity condition is similar
to the definition of "C-lines" associated with a monochromatic electric or
magnetic field, which are curves in space where the polarization ellipses
degenerate to circles. However, it was noted that RS vortices of monochromatic
fields generally oscillate at optical frequencies and are therefore
unobservable while electric and magnetic C-lines are steady. Here I show that
under the additional assumption of having definite helicity, RS vortices are
not only steady but they coincide with both sets of C-lines, electric and
magnetic. The two concepts therefore become one for waves of definite frequency
and helicity. Since the definition of RS vortices is relativistically invariant
while that of C-lines is not, it may be useful to regard the vortices as a
wideband generalization of C-lines for waves of definite helicity.Comment: 5 pages, no figures. Submitted to J of Optics A, special issue on
Singular Optics; minor changes from v.
- …