Acute Effects Of 24-h Sleep Deprivation On Salivary Cortisol And Testosterone Concentrations And Testosterone To Cortisol Ratio Following Supplementation With Caffeine Or Placebo

International Journal of Exercise Science 10(1): 108-120, 2017. Caffeine has become a popular ergogenic aid amongst athletes and usage to improve athletic performance has been well documented. The effect of caffeine on anabolic and catabolic hormones in a sleep-deprived state has had little investigation to date. The purpose of the current study was to investigate the potential of caffeine to offset the effects, if any, of short-term sleep deprivation and exercise on an athlete’s testosterone and cortisol concentrations via salivary technique. Eleven competitive male athletes volunteered to be part of this prospective double-blinded study. Three test days were scheduled for each athlete; one non-sleep deprived, one sleep-deprived with caffeine supplementation (6 mg.kg-1) and one sleep-deprived with placebo ingestion. Sleep deprivation was defined as 24-h without sleep. Each test day was composed of 2 aerobic components: a modified Hoff test and a Yo-Yo test. Testosterone and cortisol concentrations were measured via salivary analysis at 4 different time-points; T1 to T4, representing baseline, and pre- and post-aerobic components, respectively. Overall no significant differences were detected comparing the different sleep states for testosterone or cortisol concentrations. A trend existed whereby the sleep-deprived with caffeine ingestion state mirrored the non-sleep deprived state for cortisol concentration. Therefore, caffeine supplementation may have potential benefits for athletes during short-term aerobic exercise when sleep-deprived. An increase in mean testosterone concentration post-aerobic exercise was only observed in the sleep-deprived with caffeine ingestion state

Prediction of Rowing Functional Threshold Power using Body Mass, Blood Lactate and GxT Peak Power Data.

International Journal of Exercise Science 16(4): 31-41, 2023. Functional Threshold Power (FTP) is a validated index of a maximal quasi steady-state cycling intensity. The central component of the FTP test is a maximal 20-min time-trial effort. A model to predict FTP from a cycling graded exercise test (m-FTP) was published that estimated FTP without the requirement of the exhaustive 20-min time-trial. The predictive model (m-FTP) was trained (developed to find the best combination of weights and bias) on a homogenous group of highly-trained cyclists and triathletes. This investigation appraised the external validity of the m-FTP model vis-à-vis the alternate modality of rowing. The reported m-FTP equation purports to be sensitive to both changing levels of fitness, and exercise capacity. To assess this claim, eighteen (7 female, 11 male) heterogeneously-conditioned rowers were recruited from regional rowing clubs. The first rowing test was a 3-min graded incremental test with a 1-min break between increments. The second test was a rowing adapted FTP test. There were no significant differences between rowing FTP (r-FTP) and m-FTP (230 ± 64 versus 233 ± 60 W, respectively, F = 1.13, P = 0.80). Computed Bland-Altman 95% LoA between r-FTP and m-FTP were (-18 W to + 15 W), sy.x was 7 W, and 95 %CI of regression were 0.97 to 0.99. The r-FTP equation was demonstrated to be effective in predicting a rowers 20-min maximum power; further appraisal of the physiological response to rowing for 60-min at the corresponding calculated FTP requires investigation

Is the FTP Test a Reliable, Reproducible and Functional Assessment Tool in Highly-Trained Athletes?

International Journal of Exercise Science 12(4): 1334-1345, 2019. The aim of the current study was to assess reliability of the Functional Threshold Power test (FTP) and the corresponding intensity sustainable for 1-hour in a “quasi-steady state”. Highly-trained athletes (n = 19) completed four non-randomized tests over successive weeks on a Wattbike; a 3-min incremental test (GxT) to exhaustion, two 20-min FTP tests and a 60-min test at computed FTP (cFTP). Power at cFTP was calculated by reducing 20-min FTP data by 5% and was compared with power at Dmax and lactate threshold (TLac). Ventilatory and blood lactate (BLa) responses to cFTP were measured to determine whether cFTP was quasi-steady state. Agreement between consecutive FTP tests was quantified using a Bland-Altman plot with 95% limits of agreement (95% LoA) set at ± 20 W. Satisfactory agreement between FTP tests was detected (95% LoA = +13 and -17 W, bias +2 W). The 60-min effort at cFTP was successfully completed by 17 participants, and BLa and ventilatory data at cFTP were classified as quasi-steady state. A 5% increase in power above cFTP destabilized BLa data (p \u3c 0.05) and prompted VO2 to increase to peak GxT rates. The FTP test is therefore deemed representative of the uppermost power a highly-trained athlete can maintain in a quasi-steady state for 60-min. Agreement between repeated 20-min FTP tests was judged acceptable

The Knowledge Development Box: An Overview

Finance Act 2015 introduced the Knowledge Development Box (KDB). The broad objective of the KDB is to promote innovation and provide an incentive whereby profits arising from patented inventions, copyrighted software and certain other specific asset classes can effectively be taxed at a reduced rate of 6.25%

Do Critical and Functional Threshold Powers Equate in Highly- Trained Athletes?

International Journal of Exercise Science 14(4): 45-59, 2021. The purpose of this investigation was to determine whether Critical Power (CP) and Functional Threshold Power (FTP) can be used interchangeably for a highly-trained group of cyclists and triathletes. CP was ascertained using multiple fixed load trials and FTP determined from a single cycling trial. Three different models for the determination of CP were initially addressed, one hyperbolic (Hmodel) and two linear (Jmodel and Imodel). The Jmodel was identified as most appropriate for a comparison with FTP. The Jmodel and FTP were not found to be interchangeable as ANOVA detected significant differences (282 ± 53 vs. 266 ± 55 W, p \u3c 0.001) between these indices and the associated Bland-Altman 95% limits of agreement exceeded those set a priori. As the Jmodel was found to be consistently higher than FTP, a correction factor was posited to anticipate CP from FTP in this homogenous group of athletes using the mean bias (16 W). An alternate method for assessing CP trial intensities using Dmax as a proxy for ventilatory threshold is also proposed. The concept of both CP and FTP representing a maximal metabolic steady-state requires further investigation as the mechanical power at CP was significantly greater than at FTP

Research & Development Tax Credit

Ireland’s R&D tax credit system is ofmajor benefit to both multinational companies and SMEs operating in Ireland. The R&D tax credit was first introduced in Finance Act 2004 and offers a company undertaking R&D in Ireland a significant tax break, representing a potential 25% refund of costs incurred.This expenditure is also allowable as a Corporation Tax deduction, giving an effective deduction of 37.5% in a company’s tax liability

Accelerated capital allowances: An overview

ACA is based on the existing capital allowances tax structure or wear and tear allowance, for plants and machinery. Claiming the ACA is carried out the same way as for the standard capital allowances. Organisations who invest in eligible energy-efficient capital equipment can deduct the full cost of the equipment from their profits in the year of purchase. This reduces the taxable profit in year one by the full cost of the equipment

Best practice : an urban village

Shelter is one of mans most basic needs and the progression of its development over time has had to deal with an ever increasingly complex world that even now places renewed demands on the way we build, live, and work. The location of the site is at Kew Bridge, London, United Kingdom. It is at the important landmark junction of Kew Bridge north circular road and Kew Bridge road, with the immediate context consisting of 3 to 4 storey high built fabric to the north and west boundaries of the site. The Kew Bridge road slipway forms the eastern boundary of the site adjacent Kew Bridge, and the River Thames forms the southern boundary of the site. The aim of the project is to evaluate the existing condition of high-rise residential developments and to compare this to leading environmentally sensitive projects, which utilise sustainable development strategies and renewable energy sources. These strategies and energy sources will be applied in the residential high-rise typology in the form of the Kew Bridge Urban Village.Dissertation (MArch (Prof))--University of Pretoria, 2005.Architectureunrestricte

Centrality Dependence of Hadron Multiplicities in Nuclear Collisions in the Dual Parton Model

We show that, even in purely soft processes, the hadronic multiplicity in nucleus-nucleus interactions contains a term that scales with the number of binary collisions. In the absence of shadowing corrections, this term dominates at mid rapidities and high energies. Shadowing corrections are calculated as a function of impact parameter and the centrality dependence of mid-rapidity multiplicities is determined. The multiplicity per participant increases with centrality with a rate that increases between SPS and RHIC energies, in agreement with experiment.Comment: 15 pages, 4 postscript figure

The decreasing radial wood stiffness pattern of some tropical trees growing in the primary forest is reversed and increases when they are grown in a plantation

International audienceBackground : This study examines the radial trend in wood stiffness of tropical rainforest trees. The objective was to determine if the type of growing environment (exposed plantation or dense primary forest) would have an effect on this radial trend. Methods : The axial elastic modulus of wood samples, representing a pith to bark cross-section, of six trees from several French Guianese species (two of Eperua falcata, one of Eperua grandiflora, two of Carapa procera and one of Symphonia gloubulifera) was measured using a dynamic "forced vibration" method. Results : Primary forest trees were observed to have a decrease in wood stiffness from pith to bark, whereas plantation trees, from the same genus or species, displayed a corresponding increase in wood stiffness. Juvenile wood stiffness appears to vary depending on the environment in which the tree had grown. Conclusion : We suggest that the growth strategy of primary forest trees is to produce wood resistant to selfbuckling so that the height of the canopy may be obtained with the maximum of efficiency. In contrast, the growth strategy of the trees growing in an exposed plantation is to produce low-stiffness wood, important to provide flexibility in wind. Further experiments to study the behaviour of more species, with more individuals per species, growing across a range of physical environments, are required