46 research outputs found
American College of Rheumatology/European League Against Rheumatism Sjögren's Syndrome Classification Criteria May Not Be Adequate for Extraglandular Disease and Necessitate Defining "Seronegative Sjögren's Syndrome": Comment on the Article by Shiboski et al.
American College of Rheumatology/European League Against Rheumatism Sjogren's Syndrome Classification Criteria May Not Be Adequate for Extraglandular Disease and Necessitate Defining ``Seronegative Sjogren's Syndrome{''}: Comment on the Article by Shiboski et al
Long-term effects of lateral wedge orthotics on hip and ankle joint space widths.
Lateral wedge insoles have been used for the treatment of medial knee osteoarthritis (OA) and have been shown to reduce loading of the medial compartment of the knee. However, as the entire lower extremity acts as a single kinetic chain, altering the biomechanics of the knee may also have significant effects at the ankles or hips. We aimed to evaluate the effects of lateral wedge orthotics on ankle and hip joints, compared to neutral orthotics, by assessing the changes in joint space width (JSW) during 36 months of continuous use
Utility of First Trimester Ultrasonography before 11 Weeks of Gestation: A Retrospective Study
Long-term effects of lateral wedge orthotics on hip and ankle joint space widths
Background: Lateral wedge insoles have been used for the treatment of
medial knee osteoarthritis (OA) and have been shown to reduce loading of
the medial compartment of the knee. However, as the entire lower
extremity acts as a single kinetic chain, altering the biomechanics of
the knee may also have significant effects at the ankles or hips. We
aimed to evaluate the effects of lateral wedge orthotics on ankle and
hip joints, compared to neutral orthotics, by assessing the changes in
joint space width (JSW) during 36 months of continuous use.
Methods: We prospectively enrolled 109 subjects with symptomatic
osteoarthritis of the medial knee according to the American College of
Rheumatology criteria. The trial was double blind and patients were
randomized to either wedged or neutral orthotic shoe inserts. Hip and
ankle JSWs were quantified using plain radiographies at baseline and at
36-months follow-up.
Findings: 45 patients completed the 36 month study. 31 of those who
completed the study were using the lateral wedge versus 14 were using
neutral orthotics. 2 patients in the wedge group had missing radiographs
and were not included in the JSW analyses. There were no significant
differences between the wedge and the neutral orthotics groups in the
magnitude of JSW change at either the hip or the ankles at 36 month.
Interpretation: We found no significant adverse effects of the lateral
wedges on ankles or hips. (C) 2016 Elsevier B.V. All rights reserved
Serum ferritin as an activity marker for granulamotosis with polyangiitis.
Serum ferritin correlates well with the activities of systemic lupus erythematosus (SLE) and dermatomyositis, but it has not been previously studied in patients with vasculitis
Cardiac dimensions during extracorporeal membrane oxygenation.
Contains fulltext :
48407.pdf (publisher's version ) (Closed access)Our aim was to analyze left ventricular fractional shortening during extracorporeal membrane oxygenation under the influence of changing volume loading conditions induced by a ductal left-to-right shunt. In all patients, the fractional shortening was observed using echocardiography before, during, and after bypass, irrespective of the presence or absence of the ductal left-to-right shunt. During membrane oxygenation, there was a significant decrease in fractional shortening (p less than 0.001), with no difference before and after membrane oxygenation. A greater decrease in fractional shortening was observed in the group with a ductal left-to-right shunt when compared to patients lacking the ductal shunt (p less than 0.006). The diastolic diameter of the left ventricle also increased significantly during the membrane oxygenation in those patients with left-to-right ductal shunting. Moreover, the patients with left-to-right shunting showed a very severe decreased fractional shortening, lower than 10 per cent, with significantly greater frequency (p less than 0.05) during the course of membrane oxygenation. Conclusion: An important decrease in left ventricular fractional shortening is observed during veno-arterial extracorporeal membrane oxygenation. Left-to-right shunting during bypass, as seen in the patients with patency of the arterial duct, increases the loading conditions on the left ventricle, and produces a significant increase in left ventricular diastolic dimensions. Despite the effects of volume loading produced by the ductal shunt during bypass, the decrease in fractional shortening is significantly more pronounced for these patients. Therefore, during membrane oxygenation the volume loading produced by the ductal shunt is unable to prevent a decrease in left ventricular fractional shortening