Everything at a glance: BAföG - Student Housing - Student Dining Counseling - Social Affairs Culture - International Affairs

Das Studentenwerk Dresden unterstützt die Studierenden als Anstalt des öffentlichen Rechts mit seinen umfangreichen Service-Angeboten ca. 40.000 Studierende von sieben Hochschulen und einer Berufsakademie an den Standorten Dresden, Tharandt, Zittau und Görlitz

Service rund ums Studium: Geschäftsbereich Oberlausitz

Das Studentenwerk Dresden ist für die Studierenden der Hochschule Zittau/Görlitz und des Internationalen Hochschulinstituts Zittau, das seit 2013 zur TU Dresden gehört, zuständig. Ganz im Sinne unseres Slogans „Zusammen. Wirken.“ arbeiten unsere Mitarbeiter in Zittau und Görlitz. Sie sorgen dafür, dass die Studierenden einen Wohnheimplatz finden, das Mensa-Essen immer frisch auf den Teller kommt und Ihr Antrag auf Ausbildungsförderung (BAföG) korrekt und zügig bearbeitet wird. Wenn Sie Fragen zur Sozial- und Rechtsberatung haben oder das Angebot der Psychosozialen Beratungsstelle nutzen möchten, kommen Sie zu „Ihrem“ Studentenwerk in Zittau oder Görlitz

Evaluation of Two Web-Based Interventions (Res-Up! and REMOTION) in Routine Outpatient Psychotherapy (Therapy Online Plus-TOP): Protocol for a Randomized Controlled Trial.

BACKGROUND Only 11%-40% of those with a mental disorder in Germany receive treatment. In many cases, face-to-face psychotherapy is not available because of limited resources, such as an insufficient number of therapists in the area. New approaches to improve the German health care system are needed to counter chronification. Web-based interventions have been shown to be effective as stand-alone and add-on treatments to routine practice. Interventions designed for a wide range of mental disorders such as transdiagnostic interventions are needed to make treatment for mental disorders more accessible and thus shorten waiting times and mitigate the chronification of mental health problems. In general, interventions can be differentiated as having either a capitalization (CAP) focus-thus drawing on already existing strengths-or a compensation (COMP) focus-trying to compensate for deficits. Up to now, the effectiveness of transdiagnostic web-based interventions with either a CAP or a COMP focus has not yet been evaluated. OBJECTIVE This study is the first to examine the effectiveness of two transdiagnostic web-based interventions: (1) the activation of resilience and drawing on existing strengths (CAP: Res-Up!) and (2) the improvement of emotion regulation (COMP: REMOTION), compared with care as usual (CAU) in routine outpatient psychotherapy. METHODS Adults with at least 1 mental health disorder will be recruited at 4 outpatient centers in Germany. Participants will then be randomized equally into 1 of the 2 intervention groups Res-Up! (CAP) and REMOTION (COMP) or into the control group (CAU). Assessments will be made at baseline (T0), at 6 weeks after treatment start (T1), and at 12 weeks after treatment start (T2). A primary outcome will be symptom severity (Brief Symptom Inventory-18). Secondary outcomes will focus on emotion regulation and resilience. RESULTS Participant recruitment and data collection started in April 2020 and were ongoing as of July 2022. We expect participants to benefit more from the interventions than from the CAU control on the dimensions of symptom severity, resilience, and emotion regulation. Furthermore, we expect to find possible differences between CAP and COMP. The results of the study are expected in 2023. CONCLUSIONS This randomized controlled trial will compare CAU with the transdiagnostic web-based interventions Res-Up! and REMOTION, and will thus inform future studies concerning the effectiveness of transdiagnostic web-based interventions in routine outpatient psychotherapy. TRIAL REGISTRATION ClinicalTrials.gov NCT04352010; https://clinicaltrials.gov/ct2/show/NCT04352010. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID) DERR1-10.2196/41413

Serum response factor is crucial for actin cytoskeletal organization and focal adhesion assembly in embryonic stem cells

The activity of serum response factor (SRF), an essential transcription factor in mouse gastrulation, is regulated by changes in actin dynamics. Using Srf(−/−) embryonic stem (ES) cells, we demonstrate that SRF deficiency causes impairments in ES cell spreading, adhesion, and migration. These defects correlate with defective formation of cytoskeletal structures, namely actin stress fibers and focal adhesion (FA) plaques. The FA proteins FA kinase (FAK), β1-integrin, talin, zyxin, and vinculin were downregulated and/or mislocalized in ES cells lacking SRF, leading to inefficient activation of the FA signaling kinase FAK. Reduced overall actin expression levels in Srf(−/−) ES cells were accompanied by an offset treadmilling equilibrium, resulting in lowered F-actin levels. Expression of active RhoA-V14 rescued F-actin synthesis but not stress fiber formation. Introduction of constitutively active SRF-VP16 into Srf(−/−) ES cells, on the other hand, strongly induced expression of FA components and F-actin synthesis, leading to a dramatic reorganization of actin filaments into stress fibers and lamellipodia. Thus, using ES cell genetics, we demonstrate for the first time the importance of SRF for the formation of actin-directed cytoskeletal structures that determine cell spreading, adhesion, and migration. Our findings suggest an involvement of SRF in cell migratory processes in multicellular organisms

Alles auf einen Blick: BAföG, Wohnen, Mensa, Beratung, Soziales, Kultur, Internationales

Das Studentenwerk Dresden unterstützt die Studierenden als Anstalt des öffentlichen Rechts mit seinen umfangreichen Service-Angeboten ca. 40.000 Studierende von sieben Hochschulen und einer Berufsakademie an den Standorten Dresden, Tharandt, Zittau und Görlitz

Quantitative single-molecule microscopy reveals that CENP-A(Cnp1) deposition occurs during G2 in fission yeast

The inheritance of the histone H3 variant CENP-A in nucleosomes at centromeres following DNA replication is mediated by an epigenetic mechanism. To understand the process of epigenetic inheritance, or propagation of histones and histone variants, as nucleosomes are disassembled and reassembled in living eukaryotic cells, we have explored the feasibility of exploiting photo-activated localization microscopy (PALM). PALM of single molecules in living cells has the potential to reveal new concepts in cell biology, providing insights into stochastic variation in cellular states. However, thus far, its use has been limited to studies in bacteria or to processes occurring near the surface of eukaryotic cells. With PALM, one literally observes and 'counts' individual molecules in cells one-by-one and this allows the recording of images with a resolution higher than that determined by the diffraction of light (the so-called super-resolution microscopy). Here, we investigate the use of different fluorophores and develop procedures to count the centromere-specific histone H3 variant CENP-A(Cnp1) with single-molecule sensitivity in fission yeast (Schizosaccharomyces pombe). The results obtained are validated by and compared with ChIP-seq analyses. Using this approach, CENP-A(Cnp1) levels at fission yeast (S. pombe) centromeres were followed as they change during the cell cycle. Our measurements show that CENP-A(Cnp1) is deposited solely during the G2 phase of the cell cycle

Walk & Feel – a New Integrated Walkability Research ApproachWalk & Feel – a New Integrated Walkability Research Approach

Walking is healthy, promotes social contacts and is a basic requirement of mobility. Nevertheless, between 1995 and 2013/14 the modal share of walking in Austria declined from 27% to 17%. However, walking is abig unknown factor in the overall transport system, as it is statistically often unrecorded. This also expresses an underestimation of the importance and positive effects of walking in the overall transport system. The term “walkability” is often used to describe the attractiveness of walking which not only includes the path quality but also attractive and animating conditions to walk. The project presented in this paper aims to develop a methodology, which should improve the conditions for pedestrians on their daily walks and increase the quality of life. A major requirement for this purpose is a comprehensive and high-quality data basis for assessing the quality of walking – leading to more insights into the needs of pedestrians. Biosensoric technology to gather physiologic data about people’s reaction concerning walking infrastructure will support this new approach. The approach will join subjective and objective methods to create a new view about perception and emotions of pedestrians. By this means it will evaluate spatial conditions like street design, built environment, perceived safety to achieve “walkability” or a more walkable infrastructure. This contribution introduces the topic, presents the state of research concerning walkability as well as a concept of a theoretical framework of the project. This includes a methodology to collect, analyse andvisualise the collected data, and further describes technologies for sensor-based measurement of perceptions and emotions while walking. Finally, the paper gives a first glance to the web-based platform, where different data sources are combined and visualised for various user groups and purposes

La organización de la información, los lenguajes documentales y la normalización

La calidad de la información que se maneja actualmente ha aumentado debido a las nuevas tecnologías. Esta comunicación se plantea la calidad de la información que los bibliotecarios ofrecen a sus usuarios a través de diversas herramientas : control de autoridades, normalización, normas bibliográficas, lenguajes documentales y encabezamientos de materia