Меры по борьбе с экономическим спадом во Вьетнаме

Мировой финансовый кризис в 2008 г., вызванный крахом рынка ипотечных кредитов и субстандартного кредитования в США в августе 2007 г., оставил в мировой экономике серьезные последствия. Статья направлена на изучение влияния последствий мирового экономического спада в 2008-2010 гг. на экономику Вьетнама; уроков СРВ, извлеченных из борьбы с "деградацией"; изучение пакета мероприятий по предотвращению спада и повышения устойчивости экономики. Сделаны выводы о положительных результатах, а также обнаруженных недостатках в процессе реализации мер пакета

Überlegungen zu Thomas Bauer: Kultur der Ambiguität

Forschungsfragen: 1. Bestand im Vorderen Orient in der untersuchten Epoche eine Ambiguitätstoleranz wie von Bauer beschrieben? 2. Warum verfügten die Menschen in vorderorientalischen Gesellschaften der untersuchten Epoche über große Ambiguitätstoleranz? 3. Ist Ambiguitätstoleranz ein spezifisch vorderorientalisches Phänomen? 4. Warum ist die ehedem große Ambiguitätstoleranz im Vorderen Orient verloren gegangen

Heroes and Villains: Erinnerungskultur in der zeitgenössischen Türkei

Die Geschichtsbetrachtung in der zeitgenössischen Türkei ist in den letzten Jahren intensiv erforscht worden. Im Zentrum dieser Arbeiten stand dabei, angefangen bei der Arbeit Martin Strohmeiers zur Erfor- schung der Seldschukenzeit, stets die Funktion, die der älteren türki- schen Geschichte bei der Schaffung einer neuen nationalen Identität in der republikanischen Türkei zugewiesen wurde

Handlebar injuries in children

Introduction: Handlebar injuries in children may lead to severe organ lesions despite minimal initial signs and without visible skin bruise. We present our experiences applying a diagnostic and therapeutic algorithm for blunt abdominal trauma, and present the history of two selected cases. Materials and methods: We retrospectively assessed the charts of children below 16years of age, only who were observed for 24h or more in our institution due to a handlebar injury between 2004 and 2011. All children were treated according to an institutional algorithm. Results: 40 patients with a median age of 9.5years were included. Diagnosed lesions were: ruptures of the liver (n=6), spleen (n=5), kidney (n=1), and pancreas (n=2), small bowel perforation (n=3), and hernias of the abdominal (n=2) or thoracic wall (n=1). Surgical interventions were performed in 8 patients. The outcome was favorable in all the cases. Overall median hospitalization duration was 4.5days (range 1-19days). The overall duration between the accident and arrival at our emergency unit was 2.75h (median, range 1-19h). 20 children presented directly at our emergency unit after a median of 1.7h (range 1-19.5h). 20 children were referred by a family physician or a primary hospital after a median of 4.0h (range 1-46h). Conclusion: Handlebar injuries in children resulted in serious trunk lesions in half of the present patient series. The spectrum of injuries in handlebar accidents varies widely, especially injuries to the abdomen can unmask often only in the course. We advocate close observation of patients with thoracic and abdominal handlebar injuries which may be regarded as blunt stab wounds. An institutional algorithm for blunt abdominal trauma management is supportive for emergency care in patients with handlebar injurie

TUBA Nova - A novel industrial EB-PVD coater platform for state-of-the-art TBCs and multi-layer coatings

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Alterations in Platelet Alpha-Granule Secretion and Adhesion on Collagen under Flow in Mice Lacking the Atypical Rho GTPase RhoBTB3

Typical Rho GTPases, such as Rac1, Cdc42, and RhoA, act as molecular switches regulating various aspects of platelet cytoskeleton reorganization. The loss of these enzymes results in reduced platelet functionality. Atypical Rho GTPases of the RhoBTB subfamily are characterized by divergent domain architecture. One family member, RhoBTB3, is expressed in platelets, but its function is unclear. In the present study we examined the role of RhoBTB3 in platelet function using a knockout mouse model. We found the platelet count, size, numbers of both alpha and dense granules, and surface receptor profile in these mice were comparable to wild-type mice. Deletion of Rhobtb3 had no effect on aggregation and dense granule secretion in response to a range of agonists including thrombin, collagen, and adenosine diphosphate (ADP). By contrast, alpha-granule secretion increased in mice lacking RhoBTB3 in response to thrombin, collagen related peptide (CRP) and U46619/ADP. Integrin activation and spreading on fibrinogen and collagen under static conditions were also unimpaired; however, we observed reduced platelet accrual on collagen under flow conditions. These defects did not translate into alterations in tail bleeding time. We conclude that genetic deletion of Rhobtb3 leads to subtle alterations in alpha-granule secretion and adhesion to collagen without significant effects on hemostasis in vivo