Natural linewidth analysis of d-band photoemission from Ag(110)

We report a high-resolution angle-resolved study of photoemission linewidths observed for Ag(110). A careful data analysis yields k$-resolved upper limits for the inverse inelastic lifetimes of$d$-holes at the X-point of the bulk band structure. At the upper$d$-band edge the hole-lifetime is$\tau_h \geq 22 $fs, i.e. more than one order of magnitude larger than predicted for a free-electron gas. Following calculations for$d$-hole dynamics in Cu (I.\ Campillo et al., Phys. Rev. Lett., in press) we interpret the lifetime enhancement by a small scattering cross-section of $d$- and $sp$-states below the Fermi level. With increasing distance to $E_F$ the $d$-hole lifetimes get shorter because of the rapidly increasing density of d-states and contributions of intra-$d$-band scattering processes, but remain clearly above free-electron-model predictions.Comment: 14 pages, 7 figure

Dielectrophoresis-Driven Spreading of Immersed Liquid Droplets

In recent years electrowetting-on-dielectric (EWOD) has become an effective tool to control partial wetting. EWOD uses the liquid−solid interface as part of a capacitive structure that allows capacitive and interfacial energies to adjust by changes in wetting when the liquid−solid interface is charged due to an applied voltage. An important aspect of EWOD has been its applications in micro fluidics in chemistry and biology and in optical devices and displays in physics and engineering. Many of these rely on the use of a liquid droplet immersed in a second liquid due to the need either for neutral buoyancy to overcome gravity and shield against impact shocks or to encapsulate the droplet for other reasons, such as in microfluidic-based DNA analyses. Recently, it has been shown that nonwetting oleophobic surfaces can be forcibly wetted by nonconducting oils using nonuniform electric fields and an interface-localized form of liquid dielectrophoresis (dielectrowetting). Here we show that this effect can be used to create films of oil immersed in a second immiscible fluid of lower permittivity. We predict that the square of the thickness of the film should obey a simple law dependent on the square of the applied voltage and with strength dependent on the ratio of difference in permittivity to the liquid-fluid interfacial tension, Δε/γLF. This relationship is experimentally confirmed for 11 liquid−air and liquid−liquid combinations with Δε/γLF having a span of more than two orders of magnitude. We therefore provide fundamental understanding of dielectrowetting for liquid-in-liquid systems and also open up a new method to determine liquid−liquid interfacial tensions

Understanding the role of long-acting muscarinic antagonists in asthma treatment

Objective: Long-acting muscarinic antagonists (LAMAs) have been used in the treatment of obstructive pulmonary diseases for years. Long-acting muscarinic antagonists were previously mainly used as bronchodilators in chronic obstructive pulmonary disease, but the use of LAMAs in the treatment of asthma has gained great interest. There is now ample evidence of the efficacy and safety of LAMAs as add-on therapy to inhaled corticosteroid (ICS) plus long-acting β 2-agonist (LABA) combinations in patients with moderate to severe uncontrolled asthma. Long-acting muscarinic antagonists have subsequently been included in asthma guidelines. This review summarizes the scientific evidence on the use of LAMAs in asthma and aims to provide a better understanding of the role of LAMAs in the asthma treatment care algorithm and the current gaps in our knowledge. Data sources: PubMed review using the following words: long-acting muscarinic antagonists, asthma, muscarinic receptors, tiotropium, glycopyrronium, umeclidinium. Study selections: This review focused on the key trials that led to the inclusion of LAMAs in asthma guidelines. In addition, we highlighted a number of studies with other study designs and populations. Results: We identified 6 major studies that led to inclusion in asthma guidelines and 3 studies with other study designs and populations. Conclusion: Long-acting muscarinic antagonists add-on therapy to ICS-LABA improves lung function, reduces exacerbations, and modestly improves asthma control in patients with moderate to severe asthma who are uncontrolled despite the use of ICS-LABA. Long-acting muscarinic antagonists are effective in all asthma phenotypes and endotypes

Enumeration of maps with self avoiding loops and the O(n) model on random lattices of all topologies

We compute the generating functions of a O(n) model (loop gas model) on a random lattice of any topology. On the disc and the cylinder, they were already known, and here we compute all the other topologies. We find that the generating functions (and the correlation functions of the lattice) obey the topological recursion, as usual in matrix models, i.e they are given by the symplectic invariants of their spectral curve.Comment: pdflatex, 89 pages, 12 labelled figures (15 figures at all), minor correction

Detailed spectral and morphological analysis of the shell type supernova remnant RCW 86

Aim. We aim for an understanding of the morphological and spectral properties of the supernova remnant RCW 86 and for insights into the production mechanism leading to the RCW 86 very high-energy γ-ray emission. Methods. We analyzed High Energy Spectroscopic System (H.E.S.S.) data that had increased sensitivity compared to the observations presented in the RCW 86 H.E.S.S. discovery publication. Studies of the morphological correlation between the 0.5–1 keV X-ray band, the 2–5 keV X-ray band, radio, and γ-ray emissions have been performed as well as broadband modeling of the spectral energy distribution with two different emission models. Results. We present the first conclusive evidence that the TeV γ-ray emission region is shell-like based on our morphological studies. The comparison with 2–5 keV X-ray data reveals a correlation with the 0.4–50 TeV γ-ray emission. The spectrum of RCW 86 is best described by a power law with an exponential cutoff at Ecut = (3.5 ± 1.2stat) TeV and a spectral index of Γ ≈ 1.6 ± 0.2. A static leptonic one-zone model adequately describes the measured spectral energy distribution of RCW 86, with the resultant total kinetic energy of the electrons above 1 GeV being equivalent to ~0.1% of the initial kinetic energy of a Type Ia supernova explosion (1051 erg). When using a hadronic model, a magnetic field of B ≈ 100 μG is needed to represent the measured data. Although this is comparable to formerly published estimates, a standard E−2 spectrum for the proton distribution cannot describe the γ-ray data. Instead, a spectral index of Γp ≈ 1.7 would be required, which implies that ∼7 × 1049/ncm−3 has been transferred into high-energy protons with the effective density ncm−3 = n/1 cm−3. This is about 10% of the kinetic energy of a typical Type Ia supernova under the assumption of a density of 1 cm−3

Grassmann Integral Representation for Spanning Hyperforests

Given a hypergraph G, we introduce a Grassmann algebra over the vertex set, and show that a class of Grassmann integrals permits an expansion in terms of spanning hyperforests. Special cases provide the generating functions for rooted and unrooted spanning (hyper)forests and spanning (hyper)trees. All these results are generalizations of Kirchhoff's matrix-tree theorem. Furthermore, we show that the class of integrals describing unrooted spanning (hyper)forests is induced by a theory with an underlying OSP(1|2) supersymmetry.Comment: 50 pages, it uses some latex macros. Accepted for publication on J. Phys.