Leeds and the Northern Arts Prize

Purpose - This paper aims to look at the nature of the relationship between the marketing of the contemporary visual arts, cultural tourism and city and urban regeneration. This exploratory study of the marketing of the contemporary visual arts in Leeds has, as its background narrative, the emergence of BritArt. Design/methodology/approach - The growth of contemporary visual arts provides the context for a case study of the Northern Art Prize, which was first awarded in 2007. Findings - The study found a number of factors for success that can aid urban renewal and city regeneration. Private sector marketing expertise levered into the management of the project was one critical success factor. Another was that private sector funding freed up marketers and artists and allowed risk-taking. Participants highlighted a lack of vision for the contemporary visual arts in the city and region and a strong desire for new collaborative working and new governance structures for the delivery of arts marketing and cultural tourism. Originality/value - The Northern Art Prize offers much for the marketing of contemporary visual arts, cultural tourism, city branding and urban renewal. Investing in and marketing of the arts is argued to serve as a stimulus that can bring a range of benefits for the business and wider community. Marketing, especially arts marketing, can help deliver social, economic and urban regeneration

Endocrine disruption in juvenile roach from English rivers: A preliminary study

Juvenile roach Rutilus rutilus from seven rivers of varying water quality were examined for evidence of endocrine disruption. The majority of roach from five of these rivers had femalelike reproductive ducts. The results suggest that juvenile, rather than adult, fish could be used in studies of endocrine disruption in wild fish populations

Investigating Engagement with In-Video Quiz Questions in a Programming Course

In-video quizzes are common in many distance learning platforms, including those from Coursera and EdX. However the effectiveness of in-video quizzes has not previously been assessed. In this paper we describe the construction and instrumentation of an Interactive Video Lecture Platform to measure student engagement with in-video quizzes. We also investigate the use of in-video quizzes as an approach to mitigate the lack of feedback available to students and lecturers in videos and traditional lectures. Finally, we evaluate the effectiveness of augmenting video with the ability to answer and receive feedback to quiz questions embedded directly within the video. We observed that student engagement with in-video questions was consistently high (71-86%) across two cohorts (N1=81, N2=84) with a rate of 1 question per 8.7 minutes of video. We identified three broad levels of engagement with the quiz questions and four motivations, including challenge seeking and completionism, which explain some of the observed behaviour. The results from this investigation demonstrate that in-video quizzes were successful in creating an engaging and interactive mode of content delivery. We recommend that in-video quizzes be used to increase the interactivity of video content as well as supporting formative assessment within a flipped classroom environment.This is the author accepted manuscript. The final version is available from IEEE via http://dx.doi.org/10.1109/TLT.2015.244437

Linkages Between the Phenologies of Jack Pine \u3ci\u3e(Pinus Banksiana)\u3c/i\u3e Foliage and Jack Pine Budworm (Lepidoptera: Tortricidae)

A field study conducted in 2001 and 2002 in the Michigan Upper Peninsula investigated seasonal associations between the development of jack pine, Pinus banksiana Lamb., and larvae of the jack pine budworm Choristoneura pinus Freeman (Lepidoptera: Tortricidae). There was almost no active relationship between post-diapause emerging second instars and elongation of vegetative shoots. Early instars were not closely synchronized with the flushing of current-year needle fascicles, which is required to optimize larval feeding. How- ever, there were close feeding and shelter relationships between early instars and year-2 pollen cone development. Associations with, and larval damage to, year-2 seed cones were dependent upon larval population size and posed only minimal and periodic threats to jack pine seed production. As a consequence, early instar jack pine budworm relied almost exclusively on pollen cones for survival. Third to fifth instars vacated pollen cones as soon as they became desiccated. Only then did these larvae start close associations with vegetative shoots. First, they excised partially emerged needles at their base, and when the needle-pairs completely escaped their fascicle sheath, the larvae fed routinely on the complete needle lamina. Late instars, pupae and adults were associated with previous years’ and current-year foliage without any apparent bias. This study has shown that it might be more practical to time insecticide strategies, which are intended to manage jack pine budworm larvae, to the tree’s phenology rather than jack pine budworm larval indices

The rodent uterotrophic assay: Critical protocol features, studies with nonyl phenols, and comparison with a yeast estrogenicity assay

The major protocol features of the immature rat uterotrophic assay have been evaluated using a range of reference chemicals. The protocol variables considered include the selection of the test species and route of chemical administration, the age of the test animals, the maintenance diet used, and the specificity of the assay for estrogens. It is concluded that three daily oral administrations of test chemicals to 21- to 22-day-old rats, followed by determination of absolute uterus weights on the fourth day, provide a sensitive and toxicologically relevant in vivo estrogenicity assay. Rats are favored over mice for reasons of toxicological practice, but the choice of test species is probably not a critical protocol variable, as evidenced by the similar sensitivity of rats and mice to the uterotrophic activity of methoxychlor. Vaginal opening is shown to be a useful, but nondefinitive, adjunct to the uterotrophic assay. The ability of test chemicals to reduce or abolish the uterotrophic response of estradiol is suggested to provide a useful extension of the uterotrophic assay for the purpose of detecting antiestrogens. The results of a series of studies on the environmental estrogen nonyl phenol (NP), and its linear isomer n -nonyl phenol, confirm that branching of the aliphatic side chain is important for activity. 17beta-Desoxyestradiol is shown to be of similar activity to estradiol in the uterotrophic assay and is suggested to represent the "parent" estrogen of NP. Benzoylation of NP and 17-desoxyestradiol did not affect their uterotrophic activity, in contrast to the enhancing effect of benzoylation on estradiol. Selected chemicals shown to be active in the immature rat uterotrophic assay were also evaluated in an in vitro yeast human estrogen receptor transactivation assay. Most of the chemicals gave similar qualitative responses to those seen in the uterotrophic assay, and the detection of the estrogen methoxychlor by the yeast assay evidenced a degree of intrinsic metabolic competence. However, the assay had a reduced ability (compared to rodents) to hydrolyze the benzoate ester of estradiol, and the estrogenic benzoate derivative of NP was not active in the yeast assay. These last results indicate that current metabolic deficiencies of in vitro estrogenicity assays will limit the value of negative data for the immediate future. The results described illustrate the intrinsic complexity of evaluating chemicals for estrogenic activities and confirm the need for rigorous attention to experimental design and criteria for assessing estrogenic activity

Evaluation of three models for predicting Venturia inaequalis ascospore release in Southern Brazil.

Ascospores of Venturia inaequalis constitute the principal source of primary inoculum for epidemics of apple black spot (scab). Mathematical models that describe ascospore release have been developed in USA, New Zealand and Italy. These models are based upon degree-day accumulation. In this work, the seasonal pattern of released ascospores of V. inaequalis in Vacaria, Brazil, was evaluated. During four apple growth seasons (2009 to 2012) the natural release of ascospores from ive orchards was recorded. The cumulative percentage of ascospore release was predicted using three different degreeday models. The released ascospore data showed the best it to the model developed in Italy, with a start date of 22 August rather than the phenological stage of apple bud break. It is concluded that in regions with warm winter temperatures, models that use bud break to initiate ascospore maturation will tend to underestimate availability of ascospores at the beginning of the apple growth season

Association between diabetes, diabetes treatment and risk of developing endometrial cancer.

BackgroundA growing body of evidence suggests that diabetes is a risk factor for endometrial cancer incidence. However, most of these studies used case-control study designs and did not adjust for obesity, an established risk factor for endometrial cancer. In addition, few epidemiological studies have examined the association between diabetes treatment and endometrial cancer risk. The objective of this study was to assess the relationships among diabetes, diabetes treatment and endometrial cancer risk in postmenopausal women participating in the Women's Health Initiative (WHI).MethodsA total of 88 107 postmenopausal women aged 50-79 years who were free of cancer and had no hysterectomy at baseline were followed until date of endometrial cancer diagnosis, death, hysterectomy or loss to follow-up, whichever came first. Endometrial cancers were confirmed by central medical record and pathology report review. Multivariate Cox proportional hazards regression models were used to estimate hazard ratios (HRs) (95% confidence interval (CI)) for diagnosis of diabetes and metformin treatment as risk factors for endometrial cancer.ResultsOver a mean of 11 years of follow-up, 1241 endometrial cancers developed. In the primary analysis that focused on prevalent diabetes at enrolment, compared with women without diabetes, women with self-reported diabetes, and the subset of women with treated diabetes, had significantly higher risk of endometrial cancer without adjusting for BMI (HR=1.44, 95% CI: 1.13-1.85 for diabetes, HR=1.57, 95% CI: 1.19-2.07 for treated diabetes). However after adjusting for BMI, the associations between diabetes, diabetes treatment, diabetes duration and the risk of endometrial cancer became non-significant. Elevated risk was noted when considering combining diabetes diagnosed at baseline and during follow-up as time-dependent exposure (HR=1.31, 95% CI: 1.08-1.59) even after adjusting for BMI. No significant association was observed between metformin use and endometrial cancer risk.ConclusionsOur results suggest that the relationship observed in previous research between diabetes and endometrial cancer incidence may be largely confounded by body weight, although some modest independent elevated risk remains

Equality: A tool for free-form equation editing

We describe a new tool, Equality, for equation entry using free-form layout of components drawn from a palette of symbols. Our approach is designed to enable learners to easily manipulate the structure of their equations, to be functional in both desktop and mobile environments, and to minimize the amount of learning required to use the tool.We present the results of a study comparing a prototype of our approach with Microsoft Equation Editor using a desktop machine. The initial results are promising with participants reporting that the mechanism is easy to learn and an easy way to manipulate their equations. We report the results of the study and the views of the participants and identify how these will inform the future development of Equality.We thank the Department for Education (United Kingdom) for their support in funding this work through the Isaac Physics project.This is the author accepted manuscript. The final version is available from IEEE via http://dx.doi.org/10.1109/ICALT.2015.3

How many children and young people with life-limiting conditions are clinically unstable? A national data linkage study

Objective: To determine the clinical stage (stable, unstable, deteriorating or dying) for children and young people (CYP) aged 0-25 years in Scotland with lifelimiting conditions (LLCs). Design: National cohort of CYP with LLCs using linked routinely collected healthcare data. Setting: Scotland. Patients: 20 436 CYP identified as having LLCs and resident in Scotland between 1 April 2009 and 31 March 2014. Main outcome: Clinical stage based on emergency inpatient and intensive care unit admissions and date of death. Results: Over 2200 CYP with LLCs in Scotland were unstable, deteriorating or dying in each year. Compared with 1-year-olds to 5-year-olds, children under 1 year of age had the highest risk of instability (OR 6.4, 95% CI 5.7 to 7.1); all older age groups had lower risk. Girls were more likely to be unstable than boys (OR 1.15, 95% CI 1.06 to 1.24). CYP of South Asian (OR 1.61, 95% CI 1.28 to 2.01), Black (OR 1.58, 95% CI 1.04 to 2.41) and Other (OR 1.33, 95% CI 1.02 to 1.74) ethnicity were more likely to experience instability than White CYP. Deprivation was not a significant predictor of instability. Compared with congenital abnormalities, CYP with most other primary diagnoses had a higher risk of instability; only CYP with a primary perinatal diagnosis had significantly lower risk (OR 0.23, 95% CI 0.19 to 0.29). Conclusions: The large number of CYP with LLCs who are unstable, deteriorating or dying may benefit from input from specialist paediatric palliative care. The age group under 1 and CYP of South Asian, Black and Other ethnicities should be priority groups

Longitude : a privacy-preserving location sharing protocol for mobile applications

Location sharing services are becoming increasingly popular. Although many location sharing services allow users to set up privacy policies to control who can access their location, the use made by service providers remains a source of concern. Ideally, location sharing providers and middleware should not be able to access users’ location data without their consent. In this paper, we propose a new location sharing protocol called Longitude that eases privacy concerns by making it possible to share a user’s location data blindly and allowing the user to control who can access her location, when and to what degree of precision. The underlying cryptographic algorithms are designed for GPS-enabled mobile phones. We describe and evaluate our implementation for the Nexus One Android mobile phone