Living on the walls of super-QCD

We study BPS domain walls in four-dimensional N = 1 massive SQCD with gauge group SU (N) and F < N flavors. We propose a class of three-dimensional Chern-Simons-matter theories to describe the effective dynamics on the walls. Our proposal passes several checks, including the exact matching between its vacua and the solutions to the four-dimensional BPS domain wall equations, that we solve in the small mass regime. As the flavor mass is varied, domain walls undergo a second-order phase transition, where multiple vacua coalesce into a single one. For special values of the parameters, the phase transition exhibits supersymmetry enhancement. Our proposal includes and extends previous results in the literature, providing a complete picture of BPS domain walls for F < N massive SQCD. A similar picture holds also for SQCD with gauge group Sp (N) and F < N + 1 flavors

New record on Rushia parreyssi (Mulsant, 1856), Melandrydae Leach, 1815 and other interesting beetles of the Sierra de Prades, Tarragona (Coleoptera)

En el estudio de la mortalidad de Pinus sylvestris por estrés hídrico en el área mediterránea, se ha querido ver la relación existente entre dicha mortalidad y los artrópodos, en concreto con los coleópteros. El área ibérica escogida para realizar el estudio ha sido el Tillar, situado en la sierra de Prades, en el término de Vimbodí i Poblet (Tarragona). La zona es un bosque mixto de P. sylvestris y Quercus sp. (robles y encinas) con árboles viejos y sin manejos recientes. Para conocer la fauna de coleópteros relacionados con P. sylvestris, se ha realizado una prospección exhaustiva con trampas de interceptación de vuelo, de caída y de berlese in situ. Se ha recolectado un grupo de especies de gran interés faunístico que merecen ser comentadas independientemente del proyecto.In a study on drought-induced Pinus sylvestris mortality in the Mediterranean, we explored the relationship between trees’ mortality and arthropods, specifically with beetles. The Iberian area chosen for the study was the Tillar, located in the Sierra de Prades, nearby Vimbodí i Poblet (Tarragona). The area is in a mixed forest of P. sylvestris and Quercus sp. (oaks), including old trees and without any recent management. In order to study the fauna of beetles associated with P. sylvestris, we carried out a comprehensive survey by using flight interception traps, pitfall trap and in situ Berlese traps. We recovered a very interesting group of species which deserve to be discussed independently of the project

Evaluation of the Efficacy and Safety of an Exercise Program for Persons with Total Hip or Total Knee Replacement:Study Protocol for a Randomized Controlled Trial

Total hip replacement (THR) and total knee replacement (TKR) are among the most common elective surgical procedures. There is a large consensus on the importance of physical activity promotion for an active lifestyle in persons who underwent THR or TKR to prevent or mitigate disability and improve the quality of life (QoL) in the long term. However, there is no best practice in exercise and physical activity specifically designed for these persons. The present protocol aims to evaluate the efficacy and safety of an exercise program (6 month duration) designed for improving quality of life in people who had undergone THR or TKR. This paper describes a randomized controlled trial protocol that involves persons with THR or TKR. The participant will be randomly assigned to an intervention group or a control group. The intervention group will perform post-rehabilitation supervised training; the control group will be requested to follow the usual care. The primary outcome is QoL, measured with the Short-Form Health Survey (SF-36); Secondary outcomes are clinical, functional and lifestyle measures that may influence QoL. The results of this study could provide evidence for clinicians, exercise trainers, and policymakers toward a strategy that ensures safe and effective exercise physical activity after surgery

Protein kinase CK2 is widely expressed in follicular, Burkitt and diffuse large B-cell lymphomas and propels malignant B-cell growth.

Serine-threonine kinase CK2 is highly expressed and pivotal for survival and proliferation in multiple myeloma, chronic lymphocytic leukemia and mantle cell lymphoma. Here, we investigated the expression of \u3b1 catalytic and \u3b2 regulatory CK2 subunits by immunohistochemistry in 57 follicular (FL), 18 Burkitt (BL), 52 diffuse large B-cell (DLBCL) non-Hodgkin lymphomas (NHL) and in normal reactive follicles. In silico evaluation of available Gene Expression Profile (GEP) data sets from patients and Western blot (WB) analysis in NHL cell-lines were also performed. Moreover, the novel, clinical-grade, ATP-competitive CK2-inhibitor CX-4945 (Silmitasertib) was assayed on lymphoma cells. CK2 was detected in 98.4% of cases with a trend towards a stronger CK2\u3b1 immunostain in BL compared to FL and DLBCL. No significant differences were observed between Germinal Center B (GCB) and non-GCB DLBCL types. GEP data and WB confirmed elevated CK2 mRNA and protein levels as well as active phosphorylation of specific targets in NHL cells. CX-4945 caused a dose-dependent growth-arresting effect on GCB, non-GCB DLBCL and BL cell-lines and it efficiently shut off phosphorylation of NF-\u3baB RelA and CDC37 on CK2 target sites. Thus, CK2 is highly expressed and could represent a suitable therapeutic target in BL, FL and DLBCL NHL

Knowledge discovery in databases of biomechanical variables: application to the sit to stand motor task

BACKGROUND: The interpretation of data obtained in a movement analysis laboratory is a crucial issue in clinical contexts. Collection of such data in large databases might encourage the use of modern techniques of data mining to discover additional knowledge with automated methods. In order to maximise the size of the database, simple and low-cost experimental set-ups are preferable. The aim of this study was to extract knowledge inherent in the sit-to-stand task as performed by healthy adults, by searching relationships among measured and estimated biomechanical quantities. An automated method was applied to a large amount of data stored in a database. The sit-to-stand motor task was already shown to be adequate for determining the level of individual motor ability. METHODS: The technique of search for association rules was chosen to discover patterns as part of a Knowledge Discovery in Databases (KDD) process applied to a sit-to-stand motor task observed with a simple experimental set-up and analysed by means of a minimum measured input model. Selected parameters and variables of a database containing data from 110 healthy adults, of both genders and of a large range of age, performing the task were considered in the analysis. RESULTS: A set of rules and definitions were found characterising the patterns shared by the investigated subjects. Time events of the task turned out to be highly interdependent at least in their average values, showing a high level of repeatability of the timing of the performance of the task. CONCLUSIONS: The distinctive patterns of the sit-to-stand task found in this study, associated to those that could be found in similar studies focusing on subjects with pathologies, could be used as a reference for the functional evaluation of specific subjects performing the sit-to-stand motor task

NEW TRENDS IN THE BIOACTIVE COMPOUNDS OF MILK: A REVIEW OF THE FUNCTIONAL ACTIVITIES AND PROCESSING EFFECTS

Milk has a complex highly variable nutritional com-position based on the different species and animal breeds, together with the strategy and management of the animal feed. It is the first food consumed by chil-dren, exclusively for the initial months because it contains all the nutrients necessary for body growth and the development of cognitive functions. Consid-ering the Mediterranean diet, cow and goat milk is consumed fresh or used for the production of dairy products, while sheep and buffalo milk is used exclu-sively for cheese production. In developing countries, sheep milk or milk from particular animal species such as the yak is also used for fresh consumption and is a low-cost food source for consumers. Milk is the only raw food with a complete profile of all nutri-ents, from proteins to fats, carbohydrates, water, min-erals, and vitamins. Several bioactive compounds are present in milk or originate during protein digestion and fat fraction. Thus, milk can be defined as a func-tional food because it adapts to the definition "any food or food ingredient that can provide a health ben-efit over the traditional nutrients it contains"

Non-invertible symmetries along 4d RG flows

We explore novel examples of RG flows preserving a non-invertible self-duality symmetry. Our main focus is on $\mathcal{N}=1$ quadratic superpotential deformations of 4d $\mathcal{N}=4$ super-Yang-Mills theory with gauge algebra $\mathfrak{su}(N)$. A theory that can be obtained in this way is the so-called $\mathcal{N}=1^*$ SYM where all adjoint chiral multiplets have a mass. Such IR theory exhibits a rich structure of vacua which we thoroughly examine. Our analysis elucidates the physics of spontaneous breaking of self-duality symmetry occurring in the degenerate gapped vacua. The construction can be generalized, taking as UV starting point a theory of class $\mathcal{S}$, to demonstrate how non-invertible self-duality symmetries exist in a variety of $\mathcal{N}=1$ SCFTs. We finally apply this understanding to prove that the conifold theory has a non-invertible self-duality symmetry.Comment: 48 pages + appendices. v2: refs added and typos correcte

Nuevos datos sobre Rushia parreyssi (Mulsant, 1856), Melandrydae Leach, 1815 y otros coleópteros interesantes de la sierra de Prades, Tarragona (Coleoptera)

En el estudio de la mortalidad de Pinus sylvestris por estrés hídrico en el área mediterránea, se ha querido ver la relación existente entre dicha mortalidad y los artrópodos, en concreto con los coleópteros. El área ibérica escogida para realizar el estudio ha sido el Tillar, situado en la sierra de Prades, en el término de Vimbodí i Poblet (Tarragona). La zona es un bosque mixto de P. sylvestris y Quercus sp. (robles y encinas) con árboles viejos y sin manejos recientes. Para conocer la fauna de coleópteros relacionados con P. sylvestris, se ha realizado una prospección exhaustiva con trampas de interceptación de vuelo, de caída y de berlese in situ. Se ha recolectado un grupo de especies de gran interés faunístico que merecen ser comentadas independientemente del proyecto.In a study on drought-induced Pinus sylvestris mortality in the Mediterranean, we explored the relationship between trees' mortality and arthropods, specifically with beetles. The Iberian area chosen for the study was the Tillar, located in the Sierra de Prades, nearby Vimbodí i Poblet (Tarragona). The area is in a mixed forest of P. sylvestris and Quercus sp. (oaks), including old trees and without any recent management. In order to study the fauna of beetles associated with P. sylvestris, we carried out a comprehensive survey by using flight interception traps, pitfall trap and in situ Berlese traps. We recovered a very interesting group of species which deserve to be discussed independently of the project