Design Status of the Capillary Brine Residual in Containment Water Recovery System

One of the goals of the AES Life Support System (LSS) Project is to achieve 98% water loop closure for long duration human exploration missions beyond low Earth orbit. To meet this objective, the AES LSS Project is developing technologies to recover water from wastewater brine; highly concentrated waste products generated from a primary water recovery system. The state of the art system used aboard the International Space Station (ISS) has the potential to recover up to 85% water from unine wastewater, leaving a significant amounts of water in the waste brine, the recovery of which is critical technology gap that must be filled in order to enable long duration human exploration. Recovering water from the urine wastewater brine is complicated by the concentration of solids as water is removed from the brine, and the concentration of the corrosive, toxic chemicals used to stabilize the urine which fouls and degrades water processing hardware, and poses a hazard to operators and crew. Brine Residual in Containment (BRIC) is focused on solids management through a process of "in-place" drying - the drying of brines within the container used for final disposal. Application of in-place drying has the potential to improve the safety and reliability of the system by reducing the exposure to curew and hardware to the problematic brine residual. Through a collaboration between the NASA Johnson Space Center and Portland Status University, a novel water recovery system was developed that utilizes containment geometry to support passive capillary flow and static phase separation allowing free surface evaporation to take place in a microgravity environment. A notional design for an ISS demonstration system was developed. This paper describes the testing performed to characterize the performance of the system as well as the status of the system level design

The Historic Preservation Program in Lincoln, Nebraska and Nomination of the South Bottoms Neighborhood as a Landmark District in Lincoln, Nebraska

Across the nation, thousands of historic properties are preserved, protected, and visited each year. These historic properties and historic preservation programs work to highlight historically significant places, by not only recognizing the past, but also by working to protect the significant sites into the future so they will continue to serve as reminders and examples of the historical events that have made it notable. Currently, the Historic Preservation Program in Lincoln, Nebraska recognizes over 1,400 properties as Local Landmark Sites or Districts within Lancaster County. Through this locally organized program, these properties receive a greater level of protection and financial relief opportunities by being designated within the program. This document focuses on Lincoln’s Historic Preservation Program, with an analysis regarding how the program began, operates, and continues to protect thousands of properties within Lancaster County. Data collection regarding these properties within the program was collected for further analysis and understanding of the program’s impacts and size today. This document details the benefits and enacted guidelines found in the nomination of a property, giving examples of previously nominated local sites and districts, and how the program assisted the continuing use of designated properties. Finally, an application for the proposed nomination of a local neighborhood is completed and can be utilized as an example for how the Historic Preservation Program approves and designates new local landmark sites and districts within the county. This application serves as a visual guide for the required items and research that must be conducted to fulfill a local landmark district application for Lincoln’s Historic Preservation Program. Professional Project Advisory Committee: Professor Gordon Scholz, Chair Professor Rodrigo Cantarero Professor Daniel Piatkowsk

Beginning of Viniculture in France

Chemical analyses of ancient organic compounds absorbed into the pottery fabrics of imported Etruscan amphoras (ca. 500-475 B.C.) and into a limestone pressing platform (ca. 425-400 B.C.) at the ancient coastal port site of Lattara in southern France provide the earliest biomolecular archaeological evidence for grape wine and viniculture from this country, which is crucial to the later history of wine in Europe and the rest of the world. The data support the hypothesis that export of wine by ship from Etruria in central Italy to southern Mediterranean France fueled an ever-growing market and interest in wine there, which, in turn, as evidenced by the winepress, led to transplantation of the Eurasian grapevine and the beginning of a Celtic industry in France. Herbal and pine resin additives to the Etruscan wine point to the medicinal role of wine in antiquity, as well as a means of preserving it during marine transport

Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy.

MotivationMultiple biological clocks govern a healthy pregnancy. These biological mechanisms produce immunologic, metabolomic, proteomic, genomic and microbiomic adaptations during the course of pregnancy. Modeling the chronology of these adaptations during full-term pregnancy provides the frameworks for future studies examining deviations implicated in pregnancy-related pathologies including preterm birth and preeclampsia.ResultsWe performed a multiomics analysis of 51 samples from 17 pregnant women, delivering at term. The datasets included measurements from the immunome, transcriptome, microbiome, proteome and metabolome of samples obtained simultaneously from the same patients. Multivariate predictive modeling using the Elastic Net (EN) algorithm was used to measure the ability of each dataset to predict gestational age. Using stacked generalization, these datasets were combined into a single model. This model not only significantly increased predictive power by combining all datasets, but also revealed novel interactions between different biological modalities. Future work includes expansion of the cohort to preterm-enriched populations and in vivo analysis of immune-modulating interventions based on the mechanisms identified.Availability and implementationDatasets and scripts for reproduction of results are available through: https://nalab.stanford.edu/multiomics-pregnancy/.Supplementary informationSupplementary data are available at Bioinformatics online

Pectin-based Bioink and Bioprinting Parameter Optimization and Industrialization

Bioprinting for tissue engineering and regenerative medicine offers a promising solution to the growing demand for organ transplants. A pectin-based bioink was engineered to offer cost-effectiveness and operational simplicity. This project focuses on the commercialization and industrial production of this bioink. The bioink formulation and bioprinting parameters for extrusion-based bioprinting were optimized, as extrusion-based bioprinters are most commonly used in bioprinting. The optimization process focused on structural integrity, resolution, and cell viability. Additionally, an industrial-scale production process was designed using SuperPro Designer. The bioink formulation with optimized bioprinting parameters shows great potential for extrusion-based bioprinting with scalable manufacturing capabilities

The ATLAS TRT electronics

The ATLAS inner detector consists of three sub-systems: the pixel detector spanning the radius range 4cm-20cm, the semiconductor tracker at radii from 30 to 52 cm, and the transition radiation tracker (TRT), tracking from 56 to 107 cm. The TRT provides a combination of continuous tracking with many projective measurements based on individual drift tubes (or straws) and of electron identification based on transition radiation from fibres or foils interleaved between the straws themselves. This paper describes the on and off detector electronics for the TRT as well as the TRT portion of the data acquisition (DAQ) system