Methods for 3D Geometry Processing in the Cultural Heritage Domain

This thesis presents methods for 3D geometry processing under the aspects of cultural heritage applications. After a short overview over the relevant basics in 3D geometry processing, the present thesis investigates the digital acquisition of 3D models. A particular challenge in this context are on the one hand difficult surface or material properties of the model to be captured. On the other hand, the fully automatic reconstruction of models even with suitable surface properties that can be captured with Laser range scanners is not yet completely solved. This thesis presents two approaches to tackle these challenges. One exploits a thorough capture of the object’s appearance and a coarse reconstruction for a concise and realistic object representation even for objects with problematic surface properties like reflectivity and transparency. The other method concentrates on digitisation via Laser-range scanners and exploits 2D colour images that are typically recorded with the range images for a fully automatic registration technique. After reconstruction, the captured models are often still incomplete, exhibit holes and/or regions of insufficient sampling. In addition to that, holes are often deliberately introduced into a registered model to remove some undesired or defective surface part. In order to produce a visually appealing model, for instance for visualisation purposes, for prototype or replica production, these holes have to be detected and filled. Although completion is a well-established research field in 2D image processing and many approaches do exist for image completion, surface completion in 3D is a fairly new field of research. This thesis presents a hierarchical completion approach that employs and extends successful exemplar-based 2D image processing approaches to 3D and fills in detail-equipped surface patches into missing surface regions. In order to identify and construct suitable surface patches, selfsimilarity and coherence properties of the surface context of the hole are exploited. In addition to the reconstruction and repair, the present thesis also investigates methods for a modification of captured models via interactive modelling. In this context, modelling is regarded as a creative process, for instance for animation purposes. On the other hand, it is also demonstrated how this creative process can be used to introduce human expertise into the otherwise automatic completion process. This way, reconstructions are feasible even of objects where already the data source, the object itself, is incomplete due to corrosion, demolition, or decay.Methoden zur 3D-Geometrieverarbeitung im Kulturerbesektor In dieser Arbeit werden Methoden zur Bearbeitung von digitaler 3D-Geometrie unter besonderer Berücksichtigung des Anwendungsbereichs im Kulturerbesektor vorgestellt. Nach einem kurzen Überblick über die relevanten Grundlagen der dreidimensionalen Geometriebehandlung wird zunächst die digitale Akquise von dreidimensionalen Objekten untersucht. Eine besondere Herausforderung stellen bei der Erfassung einerseits ungünstige Oberflächen- oder Materialeigenschaften der Objekte dar (wie z.B. Reflexivität oder Transparenz), andererseits ist auch die vollautomatische Rekonstruktion von solchen Modellen, die sich verhältnismäßig problemlos mit Laser-Range Scannern erfassen lassen, immer noch nicht vollständig gelöst. Daher bilden zwei neuartige Verfahren, die diesen Herausforderungen begegnen, den Anfang. Auch nach der Registrierung sind die erfassten Datensätze in vielen Fällen unvollständig, weisen Löcher oder nicht ausreichend abgetastete Regionen auf. Darüber hinaus werden in vielen Anwendungen auch, z.B. durch Entfernen unerwünschter Oberflächenregionen, Löcher gewollt hinzugefügt. Für eine optisch ansprechende Rekonstruktion, vor allem zu Visualisierungszwecken, im Bildungs- oder Unterhaltungssektor oder zur Prototyp- und Replik-Erzeugung müssen diese Löcher zunächst automatisch detektiert und anschließend geschlossen werden. Obwohl dies im zweidimensionalen Fall der Bildbearbeitung bereits ein gut untersuchtes Forschungsfeld darstellt und vielfältige Ansätze zur automatischen Bildvervollständigung existieren, ist die Lage im dreidimensionalen Fall anders, und die Übertragung von zweidimensionalen Ansätzen in den 3D stellt vielfach eine große Herausforderung dar, die bislang keine zufriedenstellenden Lösungen erlaubt hat. Nichtsdestoweniger wird in dieser Arbeit ein hierarchisches Verfahren vorgestellt, das beispielbasierte Konzepte aus dem 2D aufgreift und Löcher in Oberflächen im 3D unter Ausnutzung von Selbstähnlichkeiten und Kohärenzeigenschaften des Oberflächenkontextes schließt. Um plausible Oberflächen zu erzeugen werden die Löcher dabei nicht nur glatt gefüllt, sondern auch feinere Details aus dem Kontext rekonstruiert. Abschließend untersucht die vorliegende Arbeit noch die Modifikation der vervollständigten Objekte durch Freiformmodellierung. Dies wird dabei zum einen als kreativer Prozess z.B. zu Animationszwecken betrachtet. Zum anderen wird aber auch untersucht, wie dieser kreative Prozess benutzt werden kann, um etwaig vorhandenes Expertenwissen in die ansonsten automatische Vervollständigung mit einfließen zu lassen. Auf diese Weise werden auch Rekonstruktionen ermöglicht von Objekten, bei denen schon die Datenquelle, also das Objekt selbst z.B. durch Korrosion oder mutwillige Zerstörung unvollständig ist

Complementary Sensory and Associative Microcircuitry in Primary Olfactory Cortex

The three-layered primary olfactory (piriform) cortex is the largest component of the olfactory cortex. Sensory and intracortical inputs converge on principal cells in the anterior piriform cortex (aPC).Wecharacterize organization principles of the sensory and intracortical microcircuitry of layer II and III principal cells in acute slices of rat aPC using laser-scanning photostimulation and fast two-photon population Ca²⁺ imaging. Layer II and III principal cells are set up on a superficial-to-deep vertical axis. We found that the position on this axis correlates with input resistance and bursting behavior. These parameters scale with distinct patterns of incorporation into sensory and associative microcircuits, resulting in a converse gradient of sensory and intracortical inputs. In layer II, sensory circuits dominate superficial cells, whereas incorporation in intracortical circuits increases with depth. Layer III pyramidal cells receive more intracortical inputs than layer II pyramidal cells, but with an asymmetric dorsal offset. This microcircuit organization results in a diverse hybrid feedforward/recurrent network of neurons integrating varying ratios of intracortical and sensory input depending on a cell’s position on the superficial-to-deep vertical axis. Since burstiness of spiking correlates with both the cell’s location on this axis and its incorporation in intracortical microcircuitry, the neuronal output mode may encode a given cell’s involvement in sensory versus associative processing

How 'situational' is judgment in situational judgment tests?

Whereas situational judgment tests (SJTs) have traditionally been conceptualized as low-fidelity simulations with an emphasis on contextualized situation descriptions and context-dependent knowledge, a recent perspective views SJTs as measures of more general domain (context-independent) knowledge. In the current research, we contrasted these 2 perspectives in 3 studies by removing the situation descriptions (i.e., item stems) from SJTs. Across studies, the traditional contextualized SJT perspective was not supported for between 43% and 71% of the items because it did not make a significant difference whether the situation description was included or not for these items. These results were replicated across construct domains, samples, and response instructions. However, there was initial evidence that judgment in SJTs was more situational when (a) items measured job knowledge and skills and (b) response options denoted context-specific rules of action. Verbal protocol analyses confirmed that high scorers on SJTs without situation descriptions relied upon general rules about the effectiveness of the responses. Implications for SJT theory, research, and design are discussed

Dendritic compartment and neuronal output mode determine pathway-specific long-term potentiation in the piriform cortex

The apical dendrite of layer 2/3 pyramidal cells in the piriform cortex receives two spatially distinct inputs: one projecting onto the distal apical dendrite in sensory layer 1a, the other targeting the proximal apical dendrite in layer 1b. We observe an expression gradient of A-type K(+) channels that weakens the backpropagating action potential-mediated depolarization in layer 1a compared with layer 1b. We find that the pairing of presynaptic and postsynaptic firing leads to significantly smaller Ca(2+) signals in the distal dendritic spines in layer 1a compared with the proximal spines in layer 1b. The consequence is a selective failure to induce long-term potentiation (LTP) in layer 1a, which can be rescued by pharmacological enhancement of action potential backpropagation. In contrast, LTP induction by pairing presynaptic and postsynaptic firing is possible in layer 1b but requires bursting of the postsynaptic cell. This output mode strongly depends on the balance of excitation and inhibition in the piriform cortex. We show, on the single-spine level, how the plasticity of functionally distinct synapses is gated by the intrinsic electrical properties of piriform cortex layer 2 pyramidal cell dendrites and the cellular output mode

Qualitative prediction of blood–brain barrier permeability on a large and refined dataset

The prediction of blood–brain barrier permeation is vitally important for the optimization of drugs targeting the central nervous system as well as for avoiding side effects of peripheral drugs. Following a previously proposed model on blood–brain barrier penetration, we calculated the cross-sectional area perpendicular to the amphiphilic axis. We obtained a high correlation between calculated and experimental cross-sectional area (r = 0.898, n = 32). Based on these results, we examined a correlation of the calculated cross-sectional area with blood–brain barrier penetration given by logBB values. We combined various literature data sets to form a large-scale logBB dataset with 362 experimental logBB values. Quantitative models were calculated using bootstrap validated multiple linear regression. Qualitative models were built by a bootstrapped random forest algorithm. Both methods found similar descriptors such as polar surface area, pKa, logP, charges and number of positive ionisable groups to be predictive for logBB. In contrast to our initial assumption, we were not able to obtain models with the cross-sectional area chosen as relevant parameter for both approaches. Comparing those two different techniques, qualitative random forest models are better suited for blood-brain barrier permeability prediction, especially when reducing the number of descriptors and using a large dataset. A random forest prediction system (ntrees = 5) based on only four descriptors yields a validated accuracy of 88%

Towards the next generation of 3D content creation

In this paper we present a novel integrated 3D editing environment that combines recent advantages in various fields of computer graphics, such as shape modelling, video-based Human Computer Interaction, force feedback and VR finemanipulation techniques. This integration allows us to create a new compelling form of 3D object creation and manipulation preserving the metaphors designers, artists and painters have accustomed to during their day to day practice. Our system comprises a novel augmented reality workbench and enables users to simultaneously perform natural fine pose determination of the edited object with one hand and model or paint the object with the other hand. The hardware setup features a non-intrusive, video-based hand tracking subsystem, see-through glasses and a 3D 6-degree of freedom input device. The possibilities delivered by our AR workbench enable us to implement traditional and recent editing metaphors in an immersive and fully threedimensional environment, as well as to develop novel approaches to 3D object interaction