L’immunothérapie combinée à la chimioembolisation transartérielle contre le HCC

Dans le contexte de la lutte contre le cancer hépatocellulaire, l'objectif principal de ce projet est d'élaborer un vecteur pouvant joindre l’immunothérapie et l’approche locale comme traitement thérapeutique. L’immunomodulateur choisi est un Ligand de STING le 2’3’cGAMP qui par stimulation des cytokines inflammatoires, déclenche la maturation des cellules dendritiques et ainsi l’activation des cellules T. l’approche locale est la chimioembolisation transartérielle (TACE) par des microsphères à élution de médicaments, provocant une hypoxie tumorale

Tridentate cobalt complexes as alternative redox couples for high-efficiency dye-sensitized solar cells

Cobalt terpyridine complexes could rival the classical triiodide/iodide redox couple as efficient alternative redox couples for dye-sensitized solar cells. Cobalt bis(2,2',6',2 ''-terpyridine) complexes enable systematic tuning of the redox potential by variation of the substituents on the terpyridine ligand to optimize the open circuit voltage and the overall photovoltaic performance of the device. A [Co-II(Cl-terpy)(2)](TFSI)(2)/[Co-III(Cl-terpy)(2)](TFSI)(3) based electrolyte in combination with the Y123 donor-pi-acceptor dye yielded a solar to electric power conversion efficiency (PCE) of 8.7% under standard air mass 1.5 global (AM 1.5G) simulated sunlight. Transient photocurrent and photovoltage decay as well as electrochemical impedance spectroscopy was used to rationalize the differences in the photovoltaic parameters of devices with iodide/triiodide and cobalt complex based redox electrolytes

VARICOCELE INDUCE OXIDATIVE STRESS AND SPERM DNA DAMAGES IN INFERTILES PATIENTS.

76th Scientific Congress of the American-Society-for-Reproductive-Medicine, ELECTR NETWORK, OCT 17-21, 2020International audienc