Limiting dynamics for spherical models of spin glasses at high temperature

We analyze the coupled non-linear integro-differential equations whose solutions is the thermodynamical limit of the empirical correlation and response functions in the Langevin dynamics for spherical p-spin disordered mean-field models. We provide a mathematically rigorous derivation of their FDT solution (for the high temperature regime) and of certain key properties of this solution, which are in agreement with earlier derivations based on physical grounds

Reduced lysosomal acid lipase activity: A new marker of liver disease severity across the clinical continuum of non-alcoholic fatty liver disease?

Lysosomal acid lipase (LAL) plays a key role in intracellular lipid metabolism. Reduced LAL activity promotes increased multi-organ lysosomal cholesterol ester storage, as observed in two recessive autosomal genetic diseases, Wolman disease and Cholesterol ester storage disease. Severe liver steatosis and accelerated liver fibrosis are common features in patients with genetic LAL deficiency. By contrast, few reliable data are available on the modulation of LAL activity in vivo and on the epigenetic and metabolic factors capable of regulating its activity in subjects without homozygous mutations of the Lipase A gene. In the last few years, a less severe and non-genetic reduction of LAL activity was reported in children and adults with non-alcoholic fatty liver disease (NAFLD), suggesting a possible role of LAL reduction in the pathogenesis and progression of the disease. Patients with NAFLD show a significant, progressive reduction of LAL activity from simple steatosis to non-alcoholic steatohepatitis and cryptogenic cirrhosis. Among cirrhosis of different etiologies, those with cryptogenic cirrhosis show the most significant reductions of LAL activity. These findings suggest that the modulation of LAL activity may become a possible new therapeutic target for patients with more advanced forms of NAFLD. Moreover, the measurement of LAL activity may represent a possible new marker of disease severity in this clinical setting

The N=1 Supersymmetric Landau Problem and its Supersymmetric Landau Level Projections: the N=1 Supersymmetric Moyal-Voros Superplane

The N=1 supersymmetric invariant Landau problem is constructed and solved. By considering Landau level projections remaining non trivial under N=1 supersymmetry transformations, the algebraic structures of the N=1 supersymmetric covariant non(anti)commutative superplane analogue of the ordinary N=0 noncommutative Moyal-Voros plane are identified

Do stochastic inhomogeneities affect dark-energy precision measurements?

The effect of a stochastic background of cosmological perturbations on the luminosity-redshift relation is computed to second order through a recently proposed covariant and gauge-invariant light-cone averaging procedure. The resulting expressions are free from both ultraviolet and infrared divergences, implying that such perturbations cannot mimic a sizable fraction of dark energy. Different averages are estimated and depend on the particular function of the luminosity distance being averaged. The energy flux, being minimally affected by perturbations at large z, is proposed as the best choice for precision estimates of dark-energy parameters. Nonetheless, its irreducible (stochastic) variance induces statistical errors on \Omega_{\Lambda}(z) typically lying in the few-percent range.Comment: 5 pages, 3 figures. Comments and references added. Typos corrected. Version accepted for publication in Phys. Rev. Let

qq-graded Heisenberg algebras and deformed supersymmetries

The notion of $q$-grading on the enveloping algebra generated by products of q-deformed Heisenberg algebras is introduced for $q$ complex number in the unit disc. Within this formulation, we consider the extension of the notion of supersymmetry in the enveloping algebra. We recover the ordinary $\mathbb{Z}_2$ grading or Grassmann parity for associative superalgebra, and a modified version of the usual supersymmetry. As a specific problem, we focus on the interesting limit $q\to -1$ for which the Arik and Coon deformation of the Heisenberg algebra allows to map fermionic modes to bosonic ones in a modified sense. Different algebraic consequences are discussed.Comment: 2 figure

Slow relaxation, dynamic transitions and extreme value statistics in disordered systems

We show that the dynamics of simple disordered models, like the directed Trap Model and the Random Energy Model, takes place at a coexistence point between active and inactive dynamical phases. We relate the presence of a dynamic phase transition in these models to the extreme value statistics of the associated random energy landscape

Harmonic oscillator in a background magnetic field in noncommutative quantum phase-space

We solve explicitly the two-dimensional harmonic oscillator and the harmonic oscillator in a background magnetic field in noncommutative phase-space without making use of any type of representation. A key observation that we make is that for a specific choice of the noncommutative parameters, the time reversal symmetry of the systems get restored since the energy spectrum becomes degenerate. This is in contrast to the noncommutative configuration space where the time reversal symmetry of the harmonic oscillator is always broken.Comment: 7 pages Late

Magnetic resonance studies of the fundamental spin-wave modes in individual submicron Cu/NiFe/Cu perpendicularly magnetized disks

Spin wave spectra of perpendicularly magnetized disks with trilayers consisting of a 100 nm permalloy (Py) layer sandwiched by two Cu layers of 30 nm, are measured individually with a Magnetic Resonance Force Microscope (MRFM). It is demonstrated by 3D micromagnetic simulations that in disks having sub-micron size diameters, the lowest energy spin wave mode of the saturated state is not spatially uniform but rather is localized at the center of the Py/Cu interface in the region of a minimum demagnetizing field

A Random Walk to a Non-Ergodic Equilibrium Concept

Random walk models, such as the trap model, continuous time random walks, and comb models exhibit weak ergodicity breaking, when the average waiting time is infinite. The open question is: what statistical mechanical theory replaces the canonical Boltzmann-Gibbs theory for such systems? In this manuscript a non-ergodic equilibrium concept is investigated, for a continuous time random walk model in a potential field. In particular we show that in the non-ergodic phase the distribution of the occupation time of the particle on a given lattice point, approaches U or W shaped distributions related to the arcsin law. We show that when conditions of detailed balance are applied, these distributions depend on the partition function of the problem, thus establishing a relation between the non-ergodic dynamics and canonical statistical mechanics. In the ergodic phase the distribution function of the occupation times approaches a delta function centered on the value predicted based on standard Boltzmann-Gibbs statistics. Relation of our work with single molecule experiments is briefly discussed.Comment: 14 pages, 6 figure

Sub-Riemannian Fast Marching in SE(2)

We propose a Fast Marching based implementation for computing sub-Riemanninan (SR) geodesics in the roto-translation group SE(2), with a metric depending on a cost induced by the image data. The key ingredient is a Riemannian approximation of the SR-metric. Then, a state of the art Fast Marching solver that is able to deal with extreme anisotropies is used to compute a SR-distance map as the solution of a corresponding eikonal equation. Subsequent backtracking on the distance map gives the geodesics. To validate the method, we consider the uniform cost case in which exact formulas for SR-geodesics are known and we show remarkable accuracy of the numerically computed SR-spheres. We also show a dramatic decrease in computational time with respect to a previous PDE-based iterative approach. Regarding image analysis applications, we show the potential of considering these data adaptive geodesics for a fully automated retinal vessel tree segmentation.Comment: CIARP 201