201 research outputs found

    Rubble Pile Characterization Model

    Get PDF
    Rubble piles created following the collapse of a building in a combat situation can significantly impact mission accomplishment, particularly in the area of movement and maneuver. Rubble characteristics must be known, for example, in order to predict the ability of a vehicle to override the collateral damage from weapon effects in urban areas. Two types of models are developed: a first-order model and a first-principles-based model. In both models, we assume complete rubblization of the building and develop a rubble profile model using the size and composition of the collapsed structure to predict the rubble volume. In both cases, this profile model includes the size of the footprint area surrounding the original building assuming that the rubble is free to expand horizontally as well as the resulting height of such a rubble pile. Empirical data is now needed to verify the predictive capabilities of these models

    Continuous Concrete Beams Reinforced With CFRP Bars.

    Get PDF
    yesThis paper reports the testing of three continuously and two simply supported concrete beams reinforced with carbon fibre reinforced polymer (CFRP) bars. The amount of CFRP reinforcement in beams tested was the main parameter investigated. A continuous concrete beam reinforced with steel bars was also tested for comparison purposes. The ACI 440.1R-06 equations are validated against the beam test results. Test results show that increasing the CFRP reinforcement ratio of the bottom layer of simply and continuously supported concrete beams is a key factor in enhancing the load capacity and controlling deflection. Continuous concrete beams reinforced with CFRP bars exhibited a remarkable wide crack over the middle support that significantly influenced their behaviour. The load capacity and deflection of CFRP simply supported concrete beams are reasonably predicted using the ACI 440.1R-06 equations. However, the potential capabilities of these equations for predicting the load capacity and deflection of continuous CFRP reinforced concrete beams have been adversely affected by the de-bonding of top CFRP bars from concrete

    The status of hepatitis C virus infection among people who inject drugs in the Middle East and North Africa.

    Get PDF
    BACKGROUND AND AIMS: People who inject drugs (PWID) are a key population at high risk of hepatitis C virus (HCV) infection. The aim of this study was to delineate the epidemiology of HCV in PWID in the Middle East and North Africa (MENA). METHODS: Syntheses of data were conducted on the standardized and systematically assembled databases of the MENA HCV Epidemiology Synthesis Project, 1989-2018. Random-effects meta-analyses and meta-regressions were performed. Meta-regression variables included country, study site, year of data collection and year of publication [to assess trends in HCV antibody prevalence over time], sample size and sampling methodology. Numbers of chronically infected PWID across MENA were estimated. The Shannon Diversity Index was calculated to assess genotype diversity. RESULTS: Based on 118 HCV antibody prevalence measures, the pooled mean prevalence in PWID for all MENA was 49.3% [95% confidence interval (CI) = 44.4-54.1%]. The country-specific pooled mean ranged from 21.7% (95% CI = 4.9-38.6%) in Tunisia to 94.2% (95% CI = 90.8-96.7%) in Libya. An estimated 221 704 PWID were chronically infected, with the largest numbers found in Iran at 68 526 and in Pakistan at 46 554. There was no statistically significant evidence for a decline in HCV antibody prevalence over time. Genotype diversity was moderate (Shannon Diversity Index of 1.01 out of 1.95; 52.1%). The pooled mean percentage for each HCV genotype was highest in genotype 3 (42.7%) and in genotype 1 (35.9%). CONCLUSION: Half of people who inject drugs in the Middle East and North Africa appear to have ever been infected with hepatitis C virus, but there are large variations in antibody prevalence among countries. In addition to > 200 000 chronically infected current people who inject drugs, there is an unknown number of people who no longer inject drugs who may have acquired hepatitis C virus during past injecting drug use. Harm reduction services must be expanded, and innovative strategies need to be employed to ensure accessibility to hepatitis C virus testing and treatment

    Biophilic architecture: a review of the rationale and outcomes

    Get PDF
    Contemporary cities have high stress levels, mental health issues, high crime levels and ill health, while the built environment shows increasing problems with urban heat island effects and air and water pollution. Emerging from these concerns is a new set of design principles and practices where nature needs to play a bigger part called “biophilic architecture”. This design approach asserts that humans have an innate connection with nature that can assist to make buildings and cities more effective human abodes. This paper examines the evidence for this innate human psychological and physiological link to nature and then assesses the emerging research supporting the multiple social, environmental and economic benefits of biophilic architecture

    The evolving SARS-CoV-2 epidemic in Africa: insights from rapidly expanding genomic surveillance

    Get PDF
    Investment in SARS-CoV-2 sequencing in Africa over the past year has led to a major increase in the number of sequences generated, now exceeding 100,000 genomes, used to track the pandemic on the continent. Our results show an increase in the number of African countries able to sequence domestically, and highlight that local sequencing enables faster turnaround time and more regular routine surveillance. Despite limitations of low testing proportions, findings from this genomic surveillance study underscore the heterogeneous nature of the pandemic and shed light on the distinct dispersal dynamics of Variants of Concern, particularly Alpha, Beta, Delta, and Omicron, on the continent. Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve, while the continent faces many emerging and re-emerging infectious disease threats. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century
    corecore