Malware detection issues, future trends and challenges: a survey

This paper focuses on the challenges and issues of detecting malware in to-day's world where cyberattacks continue to grow in number and complexity. The paper reviews current trends and technologies in malware detection and the limitations of existing detection methods such as signature-based detection and heuristic analysis. The emergence of new types of malware, such as file-less malware, is also discussed, along with the need for real-time detection and response. The research methodology used in this paper is presented, which includes a literature review of recent papers on the topic, keyword searches, and analysis and representation methods used in each study. In this paper, the authors aim to address the key issues and challenges in detecting malware today, the current trends and technologies in malware detection, and the limitations of existing methods. They also explore emerging threats and trends in malware attacks and highlight future directions for research and development in the field. To achieve this, the authors use a research methodology that involves a literature review of recent papers related to the topic. They focus on detecting and analyzing methods, as well as representation and extraction methods used in each study. Finally, they classify the literature re-view, and through reading and criticism, highlight future trends and problems in the field of malware detection

Social engineering in social network: a systematic literature review

Social engineering is hacking and manipulating people's minds to obtain access to networks and systems in order to acquire sensitive data. A social engineering attack happens when victims are unaware of the strategies utilised and how to avoid them. Although rapid developments in communication technology made communication between individuals easier and faster, on the other hand, individuals' personal and private information is likely to be available online via social networking or other services without adequate security measures to protect such sensitive data. Hackers can use social engineering to target them no matter the technology they use to protect themselves. The methods differ, and the goal is the same, which is to manipulate and deceive organisations, companies, and individuals to obtain sensitive and private in-formation that attackers can benefit from, perhaps to sell it on the dark web or steal the payment card information of victims. The current research presents the attack techniques used in social engineering, as well as ways for pre-venting social engineering assaults. The major purpose of this study is to systematically and impartially conduct a systematic review of previous research on current social engineering attacks and the methods used to reduce these attacks

The genetic landscape of autism spectrum disorder in the Middle Eastern population

Introduction: Autism spectrum disorder (ASD) is characterized by aberrations in social interaction and communication associated with repetitive behaviors and interests, with strong clinical heterogeneity. Genetic factors play an important role in ASD, but about 75% of ASD cases have an undetermined genetic risk.Methods: We extensively investigated an ASD cohort made of 102 families from the Middle Eastern population of Qatar. First, we investigated the copy number variations (CNV) contribution using genome-wide SNP arrays. Next, we employed Next Generation Sequencing (NGS) to identify de novo or inherited variants contributing to the ASD etiology and its associated comorbid conditions in families with complete trios (affected child and the parents).Results: Our analysis revealed 16 CNV regions located in genomic regions implicated in ASD. The analysis of the 88 ASD cases identified 41 genes in 39 ASD subjects with de novo (n = 24) or inherited variants (n = 22). We identified three novel de novo variants in new candidate genes for ASD (DTX4, ARMC6, and B3GNT3). Also, we have identified 15 de novo variants in genes that were previously implicated in ASD or related neurodevelopmental disorders (PHF21A, WASF1, TCF20, DEAF1, MED13, CREBBP, KDM6B,SMURF1, ADNP, CACNA1G, MYT1L, KIF13B, GRIA2, CHM, and KCNK9). Additionally, we defined eight novel recessive variants (RYR2, DNAH3, TSPYL2, UPF3B KDM5C, LYST, and WNK3), four of which were X-linked.Conclusion: Despite the ASD multifactorial etiology that hinders ASD genetic risk discovery, the number of identified novel or known putative ASD genetic variants was appreciable. Nevertheless, this study represents the first comprehensive characterization of ASD genetic risk in Qatar's Middle Eastern population

Etudes écotoxicologique et protéomique avec deux souches de Daphnia magna (crustacea, cladocera) après exposition a la Deltaméthrine (insecticide pyréthrinoïdes)

International audienc

Etude écotoxicologique de la mixture de la deltaméthrine (pesticide pyréthrinoïdes) et du malathion (pesticide Organophosphore) sur Daphnia magna (Crustacé, Cladocère)

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A Novel Missense Mutation in Causes Congenital Disorder of Glycosylation Type I (Cerebello-Ocular Syndrome)

A consanguineous Qatari family having an autosomal recessive disorder characterized by severe mental retardation, cerebellar vermis hypoplasia, retinal degeneration, optic nerve atrophy, ataxic gait, and seizures was studied for identification of the offending gene and mutation. Homozygosity mapping identified an 11.4 Mb critical interval at 4q12 to q13.2 that would contain the gene responsible for the disorder. Ten positional candidate genes were screened for pathogenic mutations, but none were identified. Next-generation exome sequencing in one affected individual identified a novel SRD5A3 missense mutation c.T744G/p.F248L, which was subsequently confirmed by Sanger sequencing, suggesting a congenital disorder of glycosylation type IQ defect. Isoelectric focusing of serum transferrin showed a type I pattern indicative of an N -glycan assembly defect. This is a novel pathogenic mutation and the first SRD5A3 missense mutation as all others are protein-truncating mutations

Enhancement of the Optical and Dielectric Properties at Low Frequency of (Sr1−xCax)5Ti4O13, (0 ≤ x ≤ 0.06) Structure Ceramics

Low loss Ruddlesden–Popper (RP) series, i.e., (Sr1−xCax)5Ti4O13, 0.0 ≤ x ≤ 0.06, has been synthesized by a mixed oxide route. In this work, the substitution of Ca2+ cation in Sr5Ti4O13 sintered ceramics was chosen to enhance the structural, optical, and dielectric properties of the product. It was found that the Ca2+ content has significant effects on enhancing the dielectric properties as compared to Mn and glass additions. It was observed that the relative density, band gap energy, and dielectric loss (tangent loss) increase while relative permittivity decreases along with Ca2+ content. High relative density (96.7%), low porosity, and high band gap energy (2.241 eV) values were obtained in (Sr1−xCax)5Ti4O13, 0.0 ≤ x ≤ 0.06 sintered ceramics. These results will play a key role in the application of dielectric resonators

New Bi-Nuclear Nickel(II) Complex-Based Salen Schiff Base: Synthesis, Crystal Structure, Spectroscopic, Thermal, and Electrical Investigations

In this study, a new bi-nuclear nickel complex [Ni2HL2(EtOH)2](Cl)(EtOH) of a Schiff base ligand, 2-[3-[2-hydroxybenzylideneamino]propyliminomethyl]phenol, was synthesized and characterized using UV/Vis, IR, HRMS, and TGA/DTA analysis. The molecular structure of the obtained complex was corroborated by the single crystal X-ray diffraction technique. It was found in the complex that two molecules of the ligand coordinate with two nickel atoms through azomethine-N and phenoxy-O, resulting in 6-coordinate distorted octahedral geometry, in which two ethanol molecules occupy the axial positions. The dielectric and electrical properties of the obtained samples were studied by impedance spectroscopy at different frequencies (from 1 Hz to 1 MHz) in the temperature range 298–343 K. It is found that the electrical conductivity of the Ni(II) complex is lower than that of the free ligand H2L, suggesting that the complexation traps the charge carriers contained in the ligand

New Bi-Nuclear Nickel(II) Complex-Based Salen Schiff Base: Synthesis, Crystal Structure, Spectroscopic, Thermal, and Electrical Investigations

In this study, a new bi-nuclear nickel complex [Ni2HL2(EtOH)2](Cl)(EtOH) of a Schiff base ligand, 2-[3-[2-hydroxybenzylideneamino]propyliminomethyl]phenol, was synthesized and characterized using UV/Vis, IR, HRMS, and TGA/DTA analysis. The molecular structure of the obtained complex was corroborated by the single crystal X-ray diffraction technique. It was found in the complex that two molecules of the ligand coordinate with two nickel atoms through azomethine-N and phenoxy-O, resulting in 6-coordinate distorted octahedral geometry, in which two ethanol molecules occupy the axial positions. The dielectric and electrical properties of the obtained samples were studied by impedance spectroscopy at different frequencies (from 1 Hz to 1 MHz) in the temperature range 298–343 K. It is found that the electrical conductivity of the Ni(II) complex is lower than that of the free ligand H2L, suggesting that the complexation traps the charge carriers contained in the ligand