Exotic and excited-state radiative transitions in charmonium from lattice QCD

We compute, for the first time using lattice QCD methods, radiative transition rates involving excited charmonium states, states of high spin and exotics. Utilizing a large basis of interpolating fields we are able to project out various excited state contributions to three-point correlators computed on quenched anisotropic lattices. In the first lattice QCD calculation of the exotic 1-+ eta_c1 radiative decay, we find a large partial width Gamma(eta_c1 -> J/psi gamma) ~ 100 keV. We find clear signals for electric dipole and magnetic quadrupole transition form factors in chi_c2 -> J/psi gamma, calculated for the first time in this framework, and study transitions involving excited psi and chi_c1,2 states. We calculate hindered magnetic dipole transition widths without the sensitivity to assumptions made in model studies and find statistically significant signals, including a non-exotic vector hybrid candidate Y_hyb? -> eta_c gamma. As well as comparison to experimental data, we discuss in some detail the phenomenology suggested by our results and the extent to which it mirrors that of quark potential models and make suggestions for the interpretation of our results involving exotic quantum numbered states

Semântica cultural nacional através do prisma de unidades fraseológicas

The phraseological fund of language is the most valuable source of data on culture, stereotypes of national consciousness; it includes people's ideas about myths, customs, ceremonies, rituals, habits, morals, behavior. Each person belongs to the certain national culture including national traditions, language, history, literature. Economic, cultural and scientific contacts of the countries and their people increase the relevance of the topics connected with a research of cross-cultural communications, interactions and interferences of languages and cultures, studying of the language personality.Studying of how the phraseological component of language reflects the outlook characteristic of "national spirit" in the images gives a special impulse to development of phraseology. Phraseological units (PU) reproduce this outlook in processes of the speech and by that form it, becoming property of language consciousness. The addressing to PU in which figurative basis is imprinted outlook of the English and Russian linguocultural societies defines relevance of the present research.El fondo de fraseología del lenguaje es la fuente de datos más valiosa sobre la cultura, los estereotipos de la conciencia nacional; Incluye las ideas de las personas sobre mitos, costumbres, ceremonias, rituales, hábitos, moral, comportamiento. Cada persona pertenece a la cultura nacional determinada, incluidas las tradiciones nacionales, el idioma, la historia, la literatura. Los contactos económicos, culturales y científicos de los países y sus pueblos aumentan la relevancia de los temas relacionados con la investigación de las comunicaciones interculturales, las interacciones y las interferencias de idiomas y culturas, el estudio de la personalidad lingüística.El estudio de cómo el componente fraseológico del lenguaje refleja la perspectiva característica del "espíritu nacional" en las imágenes da un impulso especial al desarrollo de la fraseología. Las unidades de Phraseological (PU) reproducen esta perspectiva en los procesos del discurso y por eso lo forman, convirtiéndose en propiedad de la conciencia del lenguaje. Dirigirse a PU en el que figura figurativa está impresa la perspectiva de las sociedades linguoculturales inglesas y rusas define la relevancia de la presente investigación.O fundo de fraseologia da linguagem é a fonte mais valiosa de dados sobre cultura, os estereótipos da consciência nacional; Inclui as idéias das pessoas sobre mitos, costumes, cerimônias, rituais, hábitos, moral, comportamento. Cada pessoa pertence à cultura nacional determinada, incluindo tradições nacionais, língua, história, literatura. Os contatos econômicos, culturais e científicos dos países e seus povos aumentam a relevância de temas relacionados à pesquisa de comunicações interculturais, às interações e interferências de línguas e culturas, ao estudo da personalidade lingüística.O estudo de como o componente fraseológico da linguagem reflete a perspectiva característica do "espírito nacional" nas imagens dá um impulso especial ao desenvolvimento da fraseologia. As unidades de fraseologia (PU) reproduzem essa perspectiva nos processos de discurso e, portanto, formam-na, tornando-se propriedade da consciência da linguagem. Dirigindo PU em que figura figurativa é impressa a perspectiva de sociedades linguísticas culturais inglesas e russas define a relevância da presente investigação

Early infant feeding and adiposity risk: from infancy to adulthood

Introduction: Systematic reviews suggest that a longer duration of breast-feeding is associated with a reduction in the risk of later overweight and obesity. Most studies examining breast-feeding in relation to adiposity have not used longitudinal analysis. In our study, we aimed to examine early infant feeding and adiposity risk in a longitudinal cohort from birth to young adulthood using new as well as published data. Methods: Data from the Western Australian Pregnancy Cohort (Raine) Study in Perth, W.A., Australia, were used to examine associations between breast-feeding and measures of adiposity at 1, 2, 3, 6, 8, 10, 14, 17, and 20 years. Results: Breast-feeding was measured in a number of ways. Longer breast-feeding (in months) was associated with reductions in weight z-scores between birth and 1 year (β = -0.027; p \u3c 0.001) in the adjusted analysis. At 3 years, breast-feeding for \u3c4 months increased the odds of infants experiencing early rapid growth (OR 2.05; 95% CI 1.43-2.94; p \u3c 0.001). From 1 to 8 years, children breast-fed for ≤4 months compared to ≥12 months had a significantly greater probability of exceeding the 95th percentile of weight. The age at which breast-feeding was stopped and a milk other than breast milk was introduced (introduction of formula milk) played a significant role in the trajectory of the BMI from birth to 14 years; the 4-month cutoff point was consistently associated with a higher BMI trajectory. Introduction of a milk other than breast milk before 6 months compared to at 6 months or later was a risk factor for being overweight or obese at 20 years of age (OR 1.47; 95% CI 1.12-1.93; p = 0.005). Discussion: Breast-feeding until 6 months of age and beyond should be encouraged and is recommended for protection against increased adiposity in childhood, adolescence, and young adulthood. Adverse long-term effects of early growth acceleration are fundamental in later overweight and obesity. Formula feeding stimulates a higher postnatal growth velocity, whereas breast-feeding promotes slower growth and a reduced likelihood of overweight and obesity. Biological mechanisms underlying the protective effect of breast-feeding against obesity are based on the unique composition and metabolic and physiological responses to human milk

Measurement of J/psi to eta_c gamma at KEDR

We present a study of the inclusive photon spectra from 5.9 million J/psi decays collected with the KEDR detector at the VEPP-4M e+e- collider. We measure the branching fraction of radiative decay J/psi to eta_c gamma, eta_c width and mass. Our preliminary results are: M(eta_c) = 2979.4+-1.5+-1.9 MeV, G(eta_c) = 27.8+-5.1+-3.3 MeV, B(J/psi to eta_c gamma) = (2.34+-0.15+-0.40)%.Comment: To be published in Proceedings of the PhiPsi09, Oct. 13-16, 2009, Beijing, Chin

Ontology of the nanoworld: system approach and the concept of evolutionism

The article deals with the ontological subsystem of the philosophical foundations of the corresponding picture of the world, defining the typical understanding of the world as a unity in a variety of properties and relations typical of a particular historical period on the basis of appropriate philosophical interpretation of such categories as matter, motion, space and time, necessary and accidental, possible and real, and other categories, attracted from the classical philosophical heritage and non-classical philosophical teaching

Fat mass and obesity-associated obesity-risk genotype is associated with lower foetal growth: An effect that is reversed in the offspring of smoking mothers

Fat mass and obesity-associated (FTO) gene variants are associated with childhood and adult obesity; however, the influence of FTO polymorphisms on foetal growth is unknown. Associations between the FTO variant rs9939609 and the foetal growth trajectories, maternal pregnancy weight gain, anthropometric measures at birth and body mass index (BMI) at age 14 years were assessed in 1079 singleton-birth Australian Caucasians. Analyses were repeated in 3512 singleton-birth Dutch Caucasians. The rs9939609 obesity-risk AA genotype was associated with symmetrical intrauterine growth restriction; an effect reversed in mothers who smoked during pregnancy. The effect increased over time and was modified by maternal smoking for head circumference (P = 0.007), abdominal circumference (P = 0.007), femur length (P = 0.02) and estimated foetal weight (P = 0.001). The modification of the association between the AA genotype and birth anthropometrics by maternal smoking was consistent across birth weight (P = 0.01) and birth length (P = 0.04) and neonatal day 2 anthropometry. Consistent associations were replicated in the Generation R cohort. Maternal pregnancy weight gain matched the pattern of birth weight and was independent of placental weight. In adolescents, the AA genotype was associated with increased BMI-adjusted-for-age in males (P = 0.00009), but no effect was detected in females. A variant in the FTO gene influences foetal growth trajectories in the third trimester, early postnatal growth and adiposity in adolescence. Maternal smoking during pregnancy reversed the direction of association of rs9939609 on foetal growth, which was probably mediated by maternal energy intake. The detection of genetic variants associated with foetal growth has the potential to identify novel molecular mechanisms underlying growth and targeted early life intervention. Copyrigh

D∗DπD^*D\pi and B∗BπB^*B\pi couplings in QCD

We calculate the $D^*D\pi$ and $B^*B\pi$ couplings using QCD sum rules on the light-cone. In this approach, the large-distance dynamics is incorporated in a set of pion wave functions. We take into account two-particle and three-particle wave functions of twist 2, 3 and 4. The resulting values of the coupling constants are $g_{D^*D\pi}= 12.5\pm 1$ and $g_{B^*B\pi}= 29\pm 3$. From this we predict the partial width \Gamma (D^{*+} \ra D^0 \pi^+ )=32 \pm 5~ keV . We also discuss the soft-pion limit of the sum rules which is equivalent to the external axial field approach employed in earlier calculations. Furthermore, using $g_{B^*B\pi}$ and $g_{D^*D\pi}$ the pole dominance model for the B \ra \pi and D\ra \pi semileptonic form factors is compared with the direct calculation of these form factors in the same framework of light-cone sum rules.Comment: 27 pages (LATEX) +3 figures enclosed as .uu file MPI-PhT/94-62 , CEBAF-TH-94-22, LMU 15/9

Regulation of GSK-3 Activity as A Shared Mechanism in Psychiatric Disorders

Serin/Treonin kinaz ailesinin üyelerinden bir kinaz olarak ilk kez glikojen sentaz’ı inhibe ettiği keşfedilen glikojen sentaz kinaz-3 (GSK-3), günümüzde bilinen 50’den fazla substratı ile birçok hücre içi düzenleyici mekanizmada görev alan geniş etki spektrumlu bir enzim olarak kabul edilmektedir. GSK-3’ün memelilerde GSK-3α ve GSK-3β olmak üzere yapısal olarak yüksek homoloji gösteren iki izoformu bulunmaktadır. Her iki izoform birçok dokuda yaygın dağılım göstermekle beraber, en yüksek oranda beyinde bulunmakta ve genellikle benzer fonksiyonlar göstermektedirler. Diğer protein kinazların aksine GSK-3 uyarılmamış hücrede yapısal olarak aktif yani defosforile halde bulur. Protein kinaz A (PKA), protein kinaz B (PKB;AKT) ve protein kinaz C (PKC) gibi diğer protein kinazlarla fosforilasyona uğrayarak olarak inaktive edilir. Günümüzde artmış GSK-3 aktivitesinin major depresyon, bipolar bozukluk, hiperaktivite bozuklukları gibi hastalıklar ve şizofreni oluşumunda rol oynayabileceğine ilişkin önemli bulgular mevcuttur. Bu nedenle söz konusu psikiyatrik hastalıklarda arttığı gösterilen GSK-3 aktivitesinin azaltılmasının tedavide umut verici bir yaklaşım olabileceği kabul edilebilir. Bu gözden geçirme çalışmasında yukarıda sözü edilen psikiyatrik hastalıkların oluşmasında görev alan GSK-3 aracılı mekanizmalara kısaca değinilerek GSK-3’ün aktivitesinin düzenlenmesinde rol oynadığı gösterilen klinikte kullanılan ilaçlara yer verilmiştir. Anahtar sözcükler: GSK-3, depresyon, bipolar bozukluk, şizofren

Body mass index, adiposity rebound and early feeding in a longitudinal cohort (Raine study)

Objective: This study examined the influence of type and duration of infant feeding on adiposity rebound and the tracking of body mass index (BMI) from birth to 14 years. Methods: A sample of 1330 individuals over eight follows-ups was drawn from the Western Australian Pregnancy Cohort (Raine) Study. Trajectories of BMI from birth to adolescence using linear mixed model (LMM) analysis investigated the influence of age breastfeeding stopped and age other milk introduced (binomial 4-month cut-point). A sub-sample of LMM predicted BMI was used to determine BMI and age at nadir for early infant feeding groups. Results: Chi square analysis between early feeding and weight status (normal weight, overweight and obese) groups found a significant difference between age breastfeeding stopped (p Conclusions: Early infant feeding was important in the timing and BMI at adiposity rebound. The relationship between infant feeding and BMI remained up to age 14 years. Although confounding factors cannot be excluded, these findings support the importance of exclusive breastfeeding for longer than four months as a protective behaviour against the development of adolescent obesity