Finite nuclear size correction to the bound-electron g factor in a hydrogenlike atom

The finite nuclear size correction to the bound-electron g factor in hydrogenlike atoms is investigated in the range Z=1-20. An analytical formula for this correction which includes the non-relativistic and dominant relativistic contributions is derived. In the case of the 1s state, the results obtained by this formula are compared with previous non-relativistic analytical and relativistic numerical calculations.Comment: 5 page

Delbruck scattering and the g-factor of a bound electron

The leading contribution of the light-by-light scattering effects to g-factor of a bound electron is derived. The corresponding amplitude is expressed in terms of low-energy Delbruck scattering of a virtual photon. The result reads Delta g = (7/216) alpha (Z alpha)^5

EMD273316 & EMD95833, type 4 phosphodiesterase inhibitors, stimulate fibroblastic-colony formation by bone marrow cells via direct inhibition of PDE4 and the induction of endogenous prostaglandin synthesis

BACKGROUND: Type 4 phosphodiesterase (PDE4) inhibitors have been shown to stimulate bone formation in vivo and to stimulate osteoblastic differentiation in vitro. As one possible mechanism for the stimulation of bone formation is the recruitment of osteoprogenitor cells from the bone marrow, we have investigated the effect of the PDE4 inhibitors EMD273316, EMD95833, EMD249615 and EMD 219906 on fibroblastic colony formation by whole bone marrow cells and on the ability of these colonies to adopt an osteoblastic phenotype. RESULTS: All four agents stimulated colony formation in a concentration dependent manner, however, in the case of EMD273316 & EMD95833, the effect was evident at lower concentrations and the addition of prostaglandin E2 (PGE2) was not necessary for maximal stimulation. It was subsequently found that co-incubation with indomethacin reduced the stimulatory effects of EMD273316 & EMD95833 but had no effect on the actions of EMD249615 and EMD 219906 and that EMD273316 & EMD95833 stimulated the synthesis of endogenous PGE2 by whole bone marrow cells whereas EMD249615 and EMD 219906 had no significant effect. CONCLUSIONS: These data suggest that EMD249615, EMD 219906, EMD273316 & EMD95833 can promote the recruitment of bone marrow osteoprogenitor cells leading to a stimulation of bone formation via their direct inhibitory effects on PDE4. The actions of EMD273316 & EMD95833 however, are augmented by their ability to stimulate endogenous prostanoids synthesis which acts synergistically with their direct effects on PDE4

Pulmonary giant cells and traumatic asphyxia

A morphometrical analysis was performed to elucidate the significance of pulmonary polynuclear giant cells as a histological sign of asphyxiation. A total of 13 cases of homicidal strangulation of throttling, 8 cases of traumatic asphyxia due to chest compression and 10 control cases (cause of death: severe head injury, no signs of aspiration or other relevant pulmonary alterations, smokers and non-smokers) were investigated. The number of alveolar macrophages containing 1 or 2 nuclei and of polynuclear giant cells per microscopic field (0.000025 cm2) was estimated and a statistical evaluation was carried out. A considerable individual variation was observed in all groups with a tendency to higher numbers of cells in cases of smokers or advanced individual age. However, no significant differences were detectable in the content of alveolar macrophages and in particular of polynuclear giant cells between the asphyxiated individuals and the controls. Since polynuclear giant cells occurred in similar amounts in healthy, functionally normal lungs of non-asphyxiated individuals, the detection of such cells cannot be regarded as a reliable indicator for asphyxiation

Mass Measurements and the Bound--Electron g Factor

The accurate determination of atomic masses and the high-precision measurement of the bound-electron g factor are prerequisites for the determination of the electron mass, which is one of the fundamental constants of nature. In the 2002 CODATA adjustment [P. J. Mohr and B. N. Taylor, Rev. Mod. Phys. 77, 1 (2005)], the values of the electron mass and the electron-proton mass ratio are mainly based on g factor measurements in combination with atomic mass measurements. In this paper, we briefly discuss the prospects for obtaining other fundamental information from bound-electron g factor measurements, we present some details of a recent investigation of two-loop binding corrections to the g factor, and we also investigate the radiative corrections in the limit of highly excited Rydberg S states with a long lifetime, where the g factor might be explored using a double resonance experiment.Comment: 13 pages, LaTeX; dedicated to Prof. H.-J. Kluge on the occasion of his 65th birthday, to appear in Int. J. Mass. Spectrometr