Species interaction between carp species in polyculture system

A three months experiment was conducted to study the species interactions of two carp species in polyculture system under supplemental feeding. Four species of fishes such as silver carp (Hypophthalmichthys molitrix), mrigal (Cirrhina cirrhosus), catla (Catla catla) and common carp (Cyprinus carpio) were cultured in four different combinations each containing two species. The combination of silver carp and mrigal in treatment 1, and silver carp and common carp in treatment 2 resulted better growth and production than other two treatments of different combinations of catla and common carp, and catla and mrigal

Optimizing seed rate for summer mungbean varieties

An experiment was conducted at the Agronomy Field Laboratory, Bangladesh Agricultural University, Mymensingh from March to June, 2007 to investigate the effect of cultivar and seed rate on morphological characters, yield attributes and yield of summer mungbean. The experiment comprised four varieties viz., BINA moog2, BINA moog5, BINA moog6 and BINA moog7 and four seed rates viz. 30, 40, 50 and 60 kg ha-1. The experiment was laid out in a randomized complete block design with four replications. Results revealed that variety and seed rate had significant effect on the studied crop characters and yield. The variety BINA moog7 showed superiority in relation to plant height, number of branches and effective pods per plant, number of seeds pod-1 compared to other varieties, which resulted in the highest seed yield both per plant and per hectare. The plant height, stover yield and number of non-effective pods per plant increased with the increase in seed rate, while branch number, number of effective pods per plant, seeds per pod, 100-seed weight, as well as seed weight per plant decreased with increasing seed rate. The higher number of branches and effective pods per plant, number of seeds pod, 100-seed weight and seed yield per plant were recorded at the rate of 30 and 40 kg seeds ha-1 and the lowest values for the above parameters were observed at the rate of 60 kg seeds ha-1. But per unit area basis, the highest seed yield was recorded in 40 kg seeds ha-1 followed by 50 kg seeds ha-1 due to accommodation of higher number of plants. BINA moog7 interacted favorably with the seed rate of 30 kg ha-1 to produce the highest seed yield

Effects of different dietary levels of vitamin E on the breeding performance of Heteropneustes fossilis (Bloch)

Experiments on the study of different dietary levels of vitamin E on the growth and breeding performance of Heteropneustes fossilis brood fish were carried out in two phases. The first phase consisted of studying its ovarian development and the second phase on breeding performance. Sixty female fishes were stocked in twelve experimental chambers of a raceway. The effects of four dietary vitamin E levels viz. 0 (served as control), 50, 100 and 200 mg/kg feed, on the somatic growth, ovarian development of brood fish and on their breeding performance were studied. Each treatment had three replications. It was observed that body growth in terms of length and weight was best with 0 mg vitamin E/kg feed and 200 mg vitamin E/kg of feed gave poorest result. The gonado-somatic index and fecundity, however, was highest in the fish fed with 100 mg vitamin E/kg of feed. In case of breeding performance such as ovulation rate, fertilization rate, hatching rate and survival rate, the best result was obtained with 200 mg vitamin E/kg of feed. The overall result of this experiment indicates that 200 mg vitamin E/kg of feed is the best vitamin E dose for H fossilis brood and vitamin E content has a positive impact on ovarian development

MEDICATION ADHERENCE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS - A CROSS-SECTIONAL STUDY

Objective: This study was conducted to determine the adherence of medications among type 2 diabetes mellitus (DM) patients. To evaluate adherence to therapy and study factors associated with non-adherence and adherence in patients with type II DM. Methods: A cross-sectional, observational study was conducted for 6 months in three hospitals. A total of 200 type II diabetic patients, who were on anti-diabetic drug therapy for at least 6 months, were enrolled. Blood glucose was measured and details of drug therapy were noted. Medication adherence was assessed using the Morisky Medication Adherence Scale and adherence scores were calculated. Results: Only 15% had high medication adherence, while 24% had moderate and 61% had low medication adherence. Only 30% were having optimally controlled glycemic levels, whereas 70% were having uncontrolled glycemic levels. Medication adherence scores were lower (reflecting lower adherence) in type II patients with uncontrolled glycemic levels than those having optimally controlled glycemic levels, but this difference was not statistically significant. Conclusion: Overall, medication adherence was low in type II diabetic patients. The study shows that to improve medication adherence, better counseling and health education of patients are required. Although several patients were adherent to therapy, adherent patients are more preferably to achieve glycemic control than nonadherent patients. Greater efforts are needed to facilitate diabetes self-management behaviors to improve patient outcomes

SYNTHESIS, IN SILICO STUDIES AND EVALUATION OF ANTIBACTERIAL ACTIVITY OF 4-SUBSTITUTED BENZYLIDENE-2-(PHENOXYMETHYL) OXAZOL-5(4H)-ONES

Objective: Arylidene-1, 3-oxazol-5-ones represent potential antibacterial agents. In the present work, a series of 4-substituted benzylidene-2- (phenoxymethyl) oxazol-5(4H)-ones were synthesized and screened for antibacterial activity against Gram-negative bacteria Escherichia coli. To explore plausible mechanisms, synthesized compounds were docked with DNA-Gyrase enzyme. Methods: All the reactants, phenoxy acetyl chloride, acetic anhydride, sodium acetate, substituted aromatic aldehydes, and glycine were triturated in a mortar by mechanical stirring. The antibacterial potentiality of the compounds was screened against E. coli using the disk diffusion method and the activity was recorded as a zone of inhibition. Results: Compound 2d, possessing 3, 4, 5-trimethoxy functionality on benzylidene ring exhibited the highest activity with 19 mm of the zone of inhibition which might be due to its higher interactions with DNA-Gyrase enzyme (ΔG-8.41 kcal/mol). Compounds 2a, 2b, and 2c exhibited moderate activity in the antimicrobial assay as well as in docking study indicating the positive contribution of substitution on benzylidene ring. Conclusion: A series of 4-substituted benzylidene-2-(phenoxymethyl) oxazol-5(4H)-ones were synthesized and evaluated for antibacterial activity. Compounds 2a, 2b, and 2c displayed moderate activity whereas 2d showed maximum zone of inhibition (19 mm). The good activity of these derivatives presumed to be due to the conformational flexibility of phenoxy methylene moiety which can be well accommodated in the target binding site

Crystal structure of (Z)-4-methylbenzyl 3-[1-(5-methylpyridin-2-yl)ethylidene]dithiocarbazate

In the title dithiocarbazate compound, C17H19N3S2, the central CN2S2 residue is essentially planar (r.m.s. deviation = 0.0288 Å) and forms dihedral angles of 9.77 (8) and 77.47 (7)° with the substituted-pyridyl and p-tolyl rings, respectively, indicating a highly twisted molecule; the dihedral angle between the rings is 85.56 (8)°. The configuration about the C=N bond is Z, which allows for the formation of an intramolecular N—H...N(pyridyl) hydrogen bond. The packing features tolyl-methyl-C—H...N(imine), pyridyl-C—H...π(tolyl) and π–π interactions [between pyridyl rings with a distance = 3.7946 (13) Å], which generates jagged supramolecular layers that stack along the b axis with no directional interactions between them

Genetic variability estimates in induced population of sesame (Sesamum indicum)

An investigation was carried out to study the nature and magnitude of induced genetic variability in sesame (Sesamum indicum L.). Seeds of three sesame genotypes, Rama, SI 1666 and IC 21706 were treated with three doses of g-rays (200 Gy, 400 Gy and 600 Gy) and four concentrations of ethyl methane sulphonate (0.5%, 1.0%, 1.5% and 2.0%), separately. Mutant generations from M1 to M2 were raised to study the extent of variability, heritability and genetic advance in mutant populations. Mutations surpassed the magnitude of variability over control population in both the generations. Genotypic and phenotypic variances were higher for sterility% and 1000-seed weight in both M1 and M2 generations. With regardless of the genotype, M1 generation professed maximum genotypic and phenotypic coefficients of variability (GCV and PCV) for number of seeds per capsule. On the contrary, in M2 generation induced populations of all the three genotypes engendered maximum GCV and PCV for seed yield per plant. High heritability for sterility percentage and 1000-seed weight coupled with high genetic advance inferred that additive gene effects were important in determining these characters and could be improved through mass selection

Potato technologies for improved food security and better income

United States Agency for International Developmen

Prediction of Cyclin-Dependent Kinase Phosphorylation Substrates

Protein phosphorylation, mediated by a family of enzymes called cyclin-dependent kinases (Cdks), plays a central role in the cell-division cycle of eukaryotes. Phosphorylation by Cdks directs the cell cycle by modifying the function of regulators of key processes such as DNA replication and mitotic progression. Here, we present a novel computational procedure to predict substrates of the cyclin-dependent kinase Cdc28 (Cdk1) in the Saccharomyces cerevisiae. Currently, most computational phosphorylation site prediction procedures focus solely on local sequence characteristics. In the present procedure, we model Cdk substrates based on both local and global characteristics of the substrates. Thus, we define the local sequence motifs that represent the Cdc28 phosphorylation sites and subsequently model clustering of these motifs within the protein sequences. This restraint reflects the observation that many known Cdk substrates contain multiple clustered phosphorylation sites. The present strategy defines a subset of the proteome that is highly enriched for Cdk substrates, as validated by comparing it to a set of bona fide, published, experimentally characterized Cdk substrates which was to our knowledge, comprehensive at the time of writing. To corroborate our model, we compared its predictions with three experimentally independent Cdk proteomic datasets and found significant overlap. Finally, we directly detected in vivo phosphorylation at Cdk motifs for selected putative substrates using mass spectrometry

Broadleaved weed management in wheat with post-emergence herbicides under strip tillage system

Conventionally wheat is grown in well prepared land followed by 3-4 full tillage which carry out degradation of natural resources and contribute to an increased cost of cultivation. Adopting strip tillage (single shallow pass) technology in wheat reduces the expenditure on field preparation and saves more than 30-60% fuel and time as well as advances the sowing time compared to conventional tillage practices (Mahal et al., 2009). But, early season weed control is critical for successful strip-till production (Mitchell et al., 2009). Moreover, weed can cause grain yield reduction in wheat by 50-80% (Montazeri et al., 2005). Both grass and broadleaved weeds infest wheat, but heavy broadleaved weed infestation causes significant wheat yield reduction (Zand et al., 2007), deteriorates the quality of wheat resulting low market value and also causes obstruction in harvesting. Broadleaved weed control in wheat could be easy and convenient if appropriate post-emergence herbicide can apply. Therefore, the study had taken to evaluate the efficacy of available post-emergence herbicides to control broadleaved weeds and to select a number of efficient post-emergence herbicides under strip tillage system