2,366 research outputs found

    Fluctuations and Non-Hermiticity in the Stochastic Approach to Quantum Spins

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    We investigate the non-equilibrium dynamics of isolated quantum spin systems via an exact mapping to classical stochastic differential equations. We show that one can address significantly larger system sizes than recently obtained, including two-dimensional systems with up to 49 spins. We demonstrate that the results for physical observables are in excellent agreement with exact results and alternative numerical techniques where available. We further develop a hybrid stochastic approach involving matrix product states. In the presence of finite numerical sampling, we show that the non-Hermitian character of the stochastic representation leads to the growth of the norm of the time-evolving quantum state and to departures for physical observables at late times. We demonstrate approaches that correct for this and discuss the prospects for further development.Comment: 5 pages, 4 figures, Supplementary Materia

    Trajectory-Resolved Weiss Fields for Quantum Spin Dynamics

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    We explore the dynamics of quantum spin systems in two and three dimensions using an exact mapping to classical stochastic processes. In recent work we explored the effectiveness of sampling around the mean field evolution as determined by a stochastically averaged Weiss field. Here, we show that this approach can be significantly extended by sampling around the instantaneous Weiss field associated with each stochastic trajectory taken separately. This trajectory-resolved approach incorporates sample to sample fluctuations and allows for longer simulation times. We demonstrate the utility of this approach for quenches in the two-dimensional and three-dimensional quantum Ising model. We show that the method is particularly advantageous in situations where the average Weiss-field vanishes, but the trajectory-resolved Weiss fields are non-zero. We discuss the connection to the gauge-P phase space approach, where the trajectory-resolved Weiss field can be interpreted as a gauge degree of freedom.Comment: 11 pages, 7 figure

    Stress patterns around distal angled implants in the all-on-four concept configuration

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    nonePurpose: The All-on-Four concept advocates immediate loading and the placement of distal implants at an angle. The purpose of this study was to do a qualitative descriptive analysis of stress patterns around the distal angled implant of the All-on-Four concept. Materials and Methods: Four photoelastic acrylic resin models, each with four implants simulating the All-on-Four configuration, were prepared. The two central implants were placed vertically and parallel in each model, and the distal implant on each side was placed at an increasing angle (0, 15, 30, and 45 degrees) in each model. The four implants were splinted by means of a cast metal bar. The photoelastic models were placed between two parallel anvils. Pairs of abutments were systematically subjected to a load by suspending 5-, 10-, and 15-kg weights from one of the anvils. Photoelastic analysis was accomplished using a circular polariscope. The fringe patterns produced in the photoelastic resin for each implant and load were photographed with a digital camera. Fringe concentrations and the highest fringe order were recorded and described for the apical, central, and coronal regions of the distal angled implant for each load scenario. Results: For the implants placed at 15- and 30-degree angles, little difference in stress patterns was observed between the central straight implant and the distal angled implant. For every load scenario and for all angulations, the lowest fringe order was recorded at the central region of the implant. The highest fringe order for the apical region was always higher than the highest fringe order for the coronal region of the implant. Markedly increased isochromatic fringe concentrations were observed in model 4, which had the distal implants placed at a 45-degree angle. Conclusion: Periimplant bone surrounding the 45-degree-angled distal abutment may be more prone to occlusal overload than bone surrounding implants with lesser tilts.non

    The Waipounamu Erosion Surface: questioning the antiquity of the New Zealand land surface and terrestrial fauna and flora

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    The Waipounamu Erosion Surface is a time-transgressive, nearly planar, wave-cut surface. It is not a peneplain. Formation of the Waipounamu Erosion Surface began in Late Cretaceous time following break-up of Gondwanaland, and continued until earliest Miocene time, during a 60 million year period of widespread tectonic quiescence, thermal subsidence and marine transgression. Sedimentary facies and geomorphological evidence suggest that the erosion surface may have eventually covered the New Zealand subcontinent (Zealandia). We can find no geological evidence to indicate that land areas were continuously present throughout the middle Cenozoic. Important implications of this conclusion are: (1) the New Zealand subcontinent was largely, or entirely, submerged and (2) New Zealand's present terrestrial fauna and flora evolved largely from fortuitous arrivals during the past 22 million years. Thus the modern terrestrial biota may not be descended from archaic ancestors residing on Zealandia when it broke away from Gondwanaland in the Cretaceous, since the terrestrial biota would have been extinguished if this landmass was submerged in Oligocene–Early Miocene time. We conclude that there is insufficient geological basis for assuming that land was continuously present in the New Zealand region through Oligocene to Early Miocene time, and we therefore contemplate the alternative possibility, complete submergence of Zealandia

    EFFECTS OF STATIC STRETCHING ON MAXIMAL ISOKINETIC TORQUE

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    The effects of 20 seconds of agonist (AGO), antagonist (ANT) or no (NO) pre-exercise stretch on concentric (CON) and eccentric (ECC) maximal isokinetic torque produced at the knee were examined. Twelve male semi-pro rugby players performed dominant isokinetic knee extension following the specified stretch protocol. One-way Repeated Measures ANOVA revealed AGO to be significantly less (p < 0.05) than the other protocols for both CON (270 28 Nm) and ECC (309 42 Nm) torque. There was no difference between the ANT or NO for either CON (303 35 Nm and 304 38 Nm, respectively) or ECC (341 40 Nm and 33644 Nm). The results support the theory that pre-exercise agonist stretching may lead to performance decrements in maximal concentric torque production

    Reproducibility of measurements of potential doubling time of tumour cells in the multicentre National Cancer Institute protocol T92-0045

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    We compared the flow cytometric measurement and analysis of the potential doubling time (Tpot) between three centres involved in the National Cancer Institute (NCI) protocol T92-0045. The primary purpose was to understand and minimize the variation within the measurement. A total of 102 specimens were selected at random from patients entered into the trial. Samples were prepared, stained, run and analysed in each centre and a single set of data analysed by all three centres. Analysis of the disc data set revealed that the measurement of labelling index (LI) was robust and reproducible. The estimation of duration of S-phase (Ts) was subject to errors of profile interpretation, particularly DNA ploidy status, and analysis. The LI dominated the variation in Tpot such that the level of final agreement, after removal of outliers and ploidy agreement, reached correlation coefficients of 0.9. The sample data showed poor agreement within each of the components of the measurement. There was some improvement when ploidy was in agreement, but correlation coefficients failed to exceed values of 0.5 for Tpot. The data suggest that observer-associated analysis of Ts and tissue processing and tumour heterogeneity were the major causes of variability in the Tpot measurement. The first two aspects can be standardized and minimized, but heterogeneity will remain a problem with biopsy techniques. © 1999 Cancer Research Campaig

    Virtual patients design and its effect on clinical reasoning and student experience : a protocol for a randomised factorial multi-centre study

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    Background Virtual Patients (VPs) are web-based representations of realistic clinical cases. They are proposed as being an optimal method for teaching clinical reasoning skills. International standards exist which define precisely what constitutes a VP. There are multiple design possibilities for VPs, however there is little formal evidence to support individual design features. The purpose of this trial is to explore the effect of two different potentially important design features on clinical reasoning skills and the student experience. These are the branching case pathways (present or absent) and structured clinical reasoning feedback (present or absent). Methods/Design This is a multi-centre randomised 2x2 factorial design study evaluating two independent variables of VP design, branching (present or absent), and structured clinical reasoning feedback (present or absent).The study will be carried out in medical student volunteers in one year group from three university medical schools in the United Kingdom, Warwick, Keele and Birmingham. There are four core musculoskeletal topics. Each case can be designed in four different ways, equating to 16 VPs required for the research. Students will be randomised to four groups, completing the four VP topics in the same order, but with each group exposed to a different VP design sequentially. All students will be exposed to the four designs. Primary outcomes are performance for each case design in a standardized fifteen item clinical reasoning assessment, integrated into each VP, which is identical for each topic. Additionally a 15-item self-reported evaluation is completed for each VP, based on a widely used EViP tool. Student patterns of use of the VPs will be recorded. In one centre, formative clinical and examination performance will be recorded, along with a self reported pre and post-intervention reasoning score, the DTI. Our power calculations indicate a sample size of 112 is required for both primary outcomes
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