3,132 research outputs found
Garment making I : household project
The subject matter context has been reviewed by Miss Essie M. Heyle, Extension Professor of Home Economics. The circular itself was arranged and re-written by Mrs. J.K. Fyer, Special Assistant in Boys' and Girls' Club Work. The drawings are by Miss Catherine Bedford, Supervisor of Art in the Columbia, Mo., public schools.--Foreword."August, 1922 (Reprinted October, 1923)."Includes index.Cover title
The Dual Feminisation of HIV/AIDS
This is an Accepted Manuscript of an article published by Taylor & Francis in Globalizations on 2011, available online: http://wwww.tandfonline.com/10.1080/14747731.2010.49302
Moderate exercise increases affinity of large very low density lipoproteins for hydrolysis by lipoprotein lipase
Context:
Postprandial triglyceride (TG) concentration is independently associated with cardiovascular disease risk. Exercise reduces postprandial TG concentrations but the mechanisms responsible are unclear.
Objective:
To determine the effects of exercise on affinity of chylomicrons, large very low density lipoproteins (VLDL1) and smaller VLDL (VLDL2) for lipoprotein lipase (LPL) mediated TG hydrolysis.
Design:
Within-participant cross-over study.
Setting:
A University metabolic investigation unit.
Participants:
Ten overweight/obese men.
Interventions:
Participants undertook two oral fat tolerance tests, separated by 7–14 days, in which they had blood taken fasting and for 4 hours after a high-fat mixed meal. On the afternoon before one test, they performed a 90-minute treadmill walk at 50% maximal oxygen uptake (EX); no exercise was performed before the control test (CON).
Main outcome measures:
Circulating TG-rich lipoprotein concentrations; affinity of chylomicrons, VLDL1, VLDL2 for LPL-mediated TG hydrolysis.
Results:
Exercise significantly reduced fasting VLDL1-TG concentration (CON: 0.49(0.33–0.72) mmol.l−1, EX: 0.36(0.22–0.59) mmol.l−1, [geometric means (95% confidence interval)]; p=0.04). Time-averaged postprandial chylomicron-TG (CON: 0.55±0.10 mmol.l−1, EX: 0.39±0.08 mmol.l−1, [mean±SEM], p=0.03) and VLDL1-TG (CON: 0.85±0.13 mmol.l−1, EX: 0.66±0.10 mmol.l−1, p=0.01) concentrations were both lower in EX than CON. Affinity of VLDL1 for LPL-mediated TG hydrolysis increased by 2.2(1.3–3.7) fold (geometric mean (95% confidence interval)) (p=0.02) in the fasted state and 2.6(1.8–2.6) fold (p=0.001) postprandially. Affinity of chylomicrons and VLDL2 was not significantly different between trials.
Conclusions:
Exercise increases affinity of VLDL1 for LPL-mediated TG hydrolysis both fasting and postprandially. This mechanism is likely to contribute to exercise's TG-lowering effect
PCR for the detection of pathogens in neonatal early onset sepsis.
BACKGROUND: A large proportion of neonates are treated for presumed bacterial sepsis with broad spectrum antibiotics even though their blood cultures subsequently show no growth. This study aimed to investigate PCR-based methods to identify pathogens not detected by conventional culture. METHODS: Whole blood samples of 208 neonates with suspected early onset sepsis were tested using a panel of multiplexed bacterial PCRs targeting Streptococcus pneumoniae, Streptococcus agalactiae (GBS), Staphylococcus aureus, Streptococcus pyogenes (GAS), Enterobacteriaceae, Enterococcus faecalis, Enterococcus faecium, Ureaplasma parvum, Ureaplasma urealyticum, Mycoplasma hominis and Mycoplasma genitalium, a 16S rRNA gene broad-range PCR and a multiplexed PCR for Candida spp. RESULTS: Two-hundred and eight samples were processed. In five of those samples, organisms were detected by conventional culture; all of those were also identified by PCR. PCR detected bacteria in 91 (45%) of the 203 samples that did not show bacterial growth in culture. S. aureus, Enterobacteriaceae and S. pneumoniae were the most frequently detected pathogens. A higher bacterial load detected by PCR was correlated positively with the number of clinical signs at presentation. CONCLUSION: Real-time PCR has the potential to be a valuable additional tool for the diagnosis of neonatal sepsis
A view from the west: a structural approach to analysing Lapita design in the Eastern Lapita Province
Plurisubharmonic polynomials and bumping
We wish to study the problem of bumping outwards a pseudoconvex, finite-type
domain \Omega\subset C^n in such a way that pseudoconvexity is preserved and
such that the lowest possible orders of contact of the bumped domain with
bdy(\Omega), at the site of the bumping, are explicitly realised. Generally,
when \Omega\subset C^n, n\geq 3, the known methods lead to bumpings with high
orders of contact -- which are not explicitly known either -- at the site of
the bumping. Precise orders are known for h-extendible/semiregular domains.
This paper is motivated by certain families of non-semiregular domains in C^3.
These families are identified by the behaviour of the least-weight
plurisubharmonic polynomial in the Catlin normal form. Accordingly, we study
how to perturb certain homogeneous plurisubharmonic polynomials without
destroying plurisubharmonicity.Comment: 24 pages; corrected typos, fixed errors in Lemma 3.3; accepted for
publication in Math.
Failure to learn from feedback underlies word learning difficulties in toddlers at risk for autism
Children’s assignment of novel words to nameless objects, over objects
whose names they know (mutual exclusivity; ME) has been described
as a driving force for vocabulary acquisition. Despite their ability to use
ME to fast-map words (Preissler & Carey, 2005), children with autism
show impaired language acquisition. We aimed to address this puzzle
by building on studies showing that correct referent selection using
ME does not lead to word learning unless ostensive feedback is
provided on the child’s object choice (Horst & Samuelson, 2008). We
found that although toddlers aged 2;0 at risk for autism can use ME to
choose the correct referent of a word, they do not benefit from feedback
for long-term retention of the word–object mapping. Further, their
difficulty using feedback is associated with their smaller receptive
vocabularies. We propose that difficulties learning from social feedback,
not lexical principles, limits vocabulary building during development
in children at risk for autism
Adding flavour to twistor strings
Twistor string theory is known to describe a wide variety of field theories
at tree-level and has proved extremely useful in making substantial progress in
perturbative gauge theory. We explore the twistor dual description of a class
of N=2 UV-finite super-Yang-Mills theories with fundamental flavour by adding
'flavour' branes to the topological B-model on super-twistor space and comment
on the appearance of these objects. Evidence for the correspondence is provided
by matching amplitudes on both sides.Comment: 6 pages; contribution to the proceedings for the European Physical
Society conference on High Energy Physics in Manchester, 19-25 July 2007. v3:
Typos correcte
Covid-19 vaccines for teenagers: conversations and consent Whatever teenagers and families decide, their views must be heard and respected
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