45 research outputs found
Spiral inflow feeding the nuclear starburst in M83, observed in H-alpha emission with the GHAFAS Fabry-Perot interferometer
We present observations of the nearby barred starburst galaxy, M83 (NGC5236),
with the new Fabry-Perot interferometer GHAFAS mounted on the 4.2 meter William
Herschel Telescope on La Palma. The unprecedented high resolution observations,
of 16 pc/FWHM, of the H-alpha-emitting gas cover the central two kpc of the
galaxy. The velocity field displays the dominant disk rotation with signatures
of gas inflow from kpc scales down to the nuclear regions. At the inner Inner
Lindblad Resonance radius of the main bar and centerd at the dynamical center
of the main galaxy disk, a nuclear rapidly
rotating disk with scale length of pc has formed. The nuclear
starburst is found in the vicinity as well as inside this nuclear disk, and our
observations confirm that gas spirals in from the outer parts to feed the
nuclear starburst, giving rise to several star formation events at different
epochs, within the central 100 pc radius of M83.Comment: Accepted for publication in ApJ Letters. High-resolution version can
be found at http://www.astro.su.se/~kambiz/DOC/paper-M83.pd
Анализ системы оплаты и стимулирования труда (на примере ООО «Левобережный СтройМаркет»)
заработная плата, фонд, оплата труда, мотивацияwages, fund, salary, motivatio
BRCA2 polymorphic stop codon K3326X and the risk of breast, prostate, and ovarian cancers
Background: The K3326X variant in BRCA2 (BRCA2*c.9976A>T; p.Lys3326*; rs11571833) has been found to be associated with small increased risks of breast cancer. However, it is not clear to what extent linkage disequilibrium with fully pathogenic mutations might account for this association. There is scant information about the effect of K3326X in other hormone-related cancers.
Methods: Using weighted logistic regression, we analyzed data from the large iCOGS study including 76 637 cancer case patients and 83 796 control patients to estimate odds ratios (ORw) and 95% confidence intervals (CIs) for K3326X variant carriers in relation to breast, ovarian, and prostate cancer risks, with weights defined as probability of not having a pathogenic BRCA2 variant. Using Cox proportional hazards modeling, we also examined the associations of K3326X with breast and ovarian cancer risks among 7183 BRCA1 variant carriers. All statistical tests were two-sided.
Results: The K3326X variant was associated with breast (ORw = 1.28, 95% CI = 1.17 to 1.40, P = 5.9x10- 6) and invasive ovarian cancer (ORw = 1.26, 95% CI = 1.10 to 1.43, P = 3.8x10-3). These associations were stronger for serous ovarian cancer and for estrogen receptor–negative breast cancer (ORw = 1.46, 95% CI = 1.2 to 1.70, P = 3.4x10-5 and ORw = 1.50, 95% CI = 1.28 to 1.76, P = 4.1x10-5, respectively). For BRCA1 mutation carriers, there was a statistically significant inverse association of the K3326X variant with risk of ovarian cancer (HR = 0.43, 95% CI = 0.22 to 0.84, P = .013) but no association with breast cancer. No association with prostate cancer was observed.
Conclusions: Our study provides evidence that the K3326X variant is associated with risk of developing breast and ovarian cancers independent of other pathogenic variants in BRCA2. Further studies are needed to determine the biological mechanism of action responsible for these associations
Antioxidant supplementation and exercise-induced oxidative stress in the 60-year-old as measured by antipyrine hydroxylates
Intra-Operative Radiotherapy – 5 Years of Experience in the Palliative Treatment of Recurrent and Advanced Head and Neck Cancers
Blockade of Nitric Oxide Synthesis Inhibits Hippocampal Hyperemia in Kainic Acid-Induced Seizures
Physico-Chemical, Biological and Therapeutic Characteristics of Electrolyzed Reduced Alkaline Water (ERAW)
Effects of peach or hybrid rootstocks on growth and cropping of two cultivars of peach trees (Emeraude and Zephyr)
Effects of peach or hybrid rootstocks on growth and cropping
of two cultivars of peach trees (Emeraude and Zephyr).
Abstract - Introduction. Rootstock is an important consideration for a productive peach
orchard, especially in a replanting situation. A peach and two hybrid rootstocks, grafted
with an early and a late-season peach cultivar, were planted and their growth compared. The
experimental area had been used since 1970, for two generations of successive peach crops.
Materials and methods. Emeraude (early-season) and Zephyr (late-season) were grafted
onto GF 305 (peach rootstock), GF 677 and Cadaman Avimag (hybrid rootstocks), and
were planted in a split-plot experimental design. Fruit yield and vegetative growth were
assessed annually. Results. Vegetative growth was greater with the hybrid rootstocks
than with the peach rootstock. Fruit production was higher with Cadaman than with GF 677,
which was higher than with GF 305. Yield differences associated with rootstocks were greater
with Emeraude in comparison with Zephyr, as suggested by the rootstock × cultivar
interaction. Discussion. Compared to the previous peach plantation on the same land,
the differences observed in this current experiment, between the peach rootstock GF 305 and
the hybrid rootstock GF 677, widened, suggesting a replanting decline with the peach
rootstock. In the given conditions, the hybrid rootstock Cadaman appeared to be better suited
than GF 677 to improving peach production