45 research outputs found

    Spiral inflow feeding the nuclear starburst in M83, observed in H-alpha emission with the GHAFAS Fabry-Perot interferometer

    Full text link
    We present observations of the nearby barred starburst galaxy, M83 (NGC5236), with the new Fabry-Perot interferometer GHAFAS mounted on the 4.2 meter William Herschel Telescope on La Palma. The unprecedented high resolution observations, of 16 pc/FWHM, of the H-alpha-emitting gas cover the central two kpc of the galaxy. The velocity field displays the dominant disk rotation with signatures of gas inflow from kpc scales down to the nuclear regions. At the inner Inner Lindblad Resonance radius of the main bar and centerd at the dynamical center of the main galaxy disk, a nuclear 5.5(±0.9)×108M5.5 (\pm 0.9) \times 10^8 M_\odot rapidly rotating disk with scale length of 60±2060 \pm 20 pc has formed. The nuclear starburst is found in the vicinity as well as inside this nuclear disk, and our observations confirm that gas spirals in from the outer parts to feed the nuclear starburst, giving rise to several star formation events at different epochs, within the central 100 pc radius of M83.Comment: Accepted for publication in ApJ Letters. High-resolution version can be found at http://www.astro.su.se/~kambiz/DOC/paper-M83.pd

    BRCA2 polymorphic stop codon K3326X and the risk of breast, prostate, and ovarian cancers

    Get PDF
    Background: The K3326X variant in BRCA2 (BRCA2*c.9976A>T; p.Lys3326*; rs11571833) has been found to be associated with small increased risks of breast cancer. However, it is not clear to what extent linkage disequilibrium with fully pathogenic mutations might account for this association. There is scant information about the effect of K3326X in other hormone-related cancers. Methods: Using weighted logistic regression, we analyzed data from the large iCOGS study including 76 637 cancer case patients and 83 796 control patients to estimate odds ratios (ORw) and 95% confidence intervals (CIs) for K3326X variant carriers in relation to breast, ovarian, and prostate cancer risks, with weights defined as probability of not having a pathogenic BRCA2 variant. Using Cox proportional hazards modeling, we also examined the associations of K3326X with breast and ovarian cancer risks among 7183 BRCA1 variant carriers. All statistical tests were two-sided. Results: The K3326X variant was associated with breast (ORw = 1.28, 95% CI = 1.17 to 1.40, P = 5.9x10- 6) and invasive ovarian cancer (ORw = 1.26, 95% CI = 1.10 to 1.43, P = 3.8x10-3). These associations were stronger for serous ovarian cancer and for estrogen receptor–negative breast cancer (ORw = 1.46, 95% CI = 1.2 to 1.70, P = 3.4x10-5 and ORw = 1.50, 95% CI = 1.28 to 1.76, P = 4.1x10-5, respectively). For BRCA1 mutation carriers, there was a statistically significant inverse association of the K3326X variant with risk of ovarian cancer (HR = 0.43, 95% CI = 0.22 to 0.84, P = .013) but no association with breast cancer. No association with prostate cancer was observed. Conclusions: Our study provides evidence that the K3326X variant is associated with risk of developing breast and ovarian cancers independent of other pathogenic variants in BRCA2. Further studies are needed to determine the biological mechanism of action responsible for these associations

    Modelos quantitativos de apoio às decisões - I

    No full text

    Effects of peach or hybrid rootstocks on growth and cropping of two cultivars of peach trees (Emeraude and Zephyr)

    No full text
    Effects of peach or hybrid rootstocks on growth and cropping of two cultivars of peach trees (Emeraude and Zephyr). Abstract - Introduction. Rootstock is an important consideration for a productive peach orchard, especially in a replanting situation. A peach and two hybrid rootstocks, grafted with an early and a late-season peach cultivar, were planted and their growth compared. The experimental area had been used since 1970, for two generations of successive peach crops. Materials and methods. Emeraude (early-season) and Zephyr (late-season) were grafted onto GF 305 (peach rootstock), GF 677 and Cadaman®^{\circledR} Avimag (hybrid rootstocks), and were planted in a split-plot experimental design. Fruit yield and vegetative growth were assessed annually. Results. Vegetative growth was greater with the hybrid rootstocks than with the peach rootstock. Fruit production was higher with Cadaman than with GF 677, which was higher than with GF 305. Yield differences associated with rootstocks were greater with Emeraude in comparison with Zephyr, as suggested by the rootstock × cultivar interaction. Discussion. Compared to the previous peach plantation on the same land, the differences observed in this current experiment, between the peach rootstock GF 305 and the hybrid rootstock GF 677, widened, suggesting a replanting decline with the peach rootstock. In the given conditions, the hybrid rootstock Cadaman appeared to be better suited than GF 677 to improving peach production
    corecore