Prediction of soil water retention properties using pore-size distribution and porosity

Several models have been suggested to link a soil's pore-size distribution to its retention properties. This paper presents a method that builds on previous techniques by incorporating porosity and particles of different sizes, shapes, and separation distances to predict soil water retention properties. Mechanisms are suggested for the determination of both the main drying and wetting paths, which incorporate an adsorbed water phase and retention hysteresis. Predicted results are then compared with measured retention data to validate the model and to provide a foundation for discussing the validity and limitations of using pore-size distributions to predict retention properties. </jats:p

Optical and Near-Infrared Observations of the Peculiar Type Ia Supernova 1999ac

We present 39 nights of optical photometry, 34 nights of infrared photometry, and 4 nights of optical spectroscopy of the Type Ia SN 1999ac. This supernova was discovered two weeks before maximum light, and observations were begun shortly thereafter. At early times its spectra resembled the unusual SN 1999aa and were characterized by very high velocities in the Ca II H and K lines, but very low velocities in the Si II 6355 A line. The optical photometry showed a slow rise to peak brightness but, quite peculiarly, was followed by a more rapid decline from maximum. Thus, the B- and V-band light curves cannot be characterized by a single stretch factor. We argue that the best measure of the nature of this object is not the decline rate parameter Delta m_15 (B). The B-V colors were unusual from 30 to 90 days after maximum light in that they evolved to bluer values at a much slower rate than normal Type Ia supernovae. The spectra and bolometric light curve indicate that this event was similar to the spectroscopically peculiar slow decliner SN 1999aa.Comment: 42 pages, 14 figures, accepted for publication in the Astronomical Journal (January 28, 2006

Haemoglobin, anaemia, dementia and cognitive decline in the elderly, a systematic review

<p>Abstract</p> <p>Background</p> <p>Anaemia may increase risk of dementia or cognitive decline. There is also evidence that high haemoglobin levels increase risk of stroke, and consequently possible cognitive impairment. The elderly are more at risk of developing dementia and are also more likely to suffer from anaemia, although there is relatively little longitudinal literature addressing this association.</p> <p>Methods</p> <p>To evaluate the evidence for any relationship between incident cognitive decline or dementia in the elderly and anaemia or haemoglobin level, we conducted a systematic review and meta-analyses of peer reviewed publications. Medline, Embase and PsychInfo were searched for English language publications between 1996 and 2006. Criteria for inclusion were longitudinal studies of subjects aged ≥65, with primary outcomes of incident dementia or cognitive decline. Other designs were excluded.</p> <p>Results</p> <p>Three papers were identified and only two were able to be combined into a meta-analysis. The pooled hazard ratio for these two studies was 1.94 (95 percent confidence intervals of 1.32–2.87) showing a significantly increased risk of incident dementia with anaemia. It was not possible to investigate the effect of higher levels of haemoglobin.</p> <p>Conclusion</p> <p>Anaemia is one factor to bear in mind when evaluating risk of incident dementia. However, there are few data available and the studies were methodologically varied so a cautionary note needs to be sounded and our primary recommendation is that further robust research be carried out.</p

Visualizing helicases unwinding DNA at the single molecule level

DNA helicases are motor proteins that catalyze the unwinding of double-stranded DNA into single-stranded DNA using the free energy from ATP hydrolysis. Single molecule approaches enable us to address detailed mechanistic questions about how such enzymes move processively along DNA. Here, an optical method has been developed to follow the unwinding of multiple DNA molecules simultaneously in real time. This was achieved by measuring the accumulation of fluorescent single-stranded DNA-binding protein on the single-stranded DNA product of the helicase, using total internal reflection fluorescence microscopy. By immobilizing either the DNA or helicase, localized increase in fluorescence provides information about the rate of unwinding and the processivity of individual enzymes. In addition, it reveals details of the unwinding process, such as pauses and bursts of activity. The generic and versatile nature of the assay makes it applicable to a variety of DNA helicases and DNA templates. The method is an important addition to the single-molecule toolbox available for studying DNA processing enzymes