Prevalence and risk factors for chronic obstructive lung disease in HIV-infected patients in the HAART era

Our results suggest a role for HIV infection itself and for current cigarette smoking in the development of respiratory symptoms and COPD in HIV-infected patients. HAART did not seem to reduce the risk of respiratory symptoms and COPD, in our cases. Thus, our results suggest that HIV-infected patients should be screened for chronic respiratory disease in order to early identify those at risk or those who need specific treatment

The interplay of wind and uplift facilitates over-water flight in facultative soaring birds.

Flying over the open sea is energetically costly for terrestrial birds. Despite this, over-water journeys of many birds, sometimes hundreds of kilometres long, are uncovered by bio-logging technology. To understand how these birds afford their flights over the open sea, we investigated the role of atmospheric conditions, specifically wind and uplift, in subsidizing over-water flight at a global scale. We first established that ΔT, the temperature difference between sea surface and air, is a meaningful proxy for uplift over water. Using this proxy, we showed that the spatio-temporal patterns of sea-crossing in terrestrial migratory birds are associated with favourable uplift conditions. We then analysed route selection over the open sea for five facultative soaring species, representative of all major migratory flyways. The birds maximized wind support when selecting their sea-crossing routes and selected greater uplift when suitable wind support was available. They also preferred routes with low long-term uncertainty in wind conditions. Our findings suggest that, in addition to wind, uplift may play a key role in the energy seascape for bird migration that in turn determines strategies and associated costs for birds crossing ecological barriers such as the open sea

Patterns of GPS Tracks Suggest Nocturnal Foraging by Incubating Peruvian Pelicans (Pelecanus thagus)

Most seabirds are diurnal foragers, but some species may also feed at night. In Peruvian pelicans (Pelecanus thagus), the evidence for nocturnal foraging is sparse and anecdotal. We used GPS-dataloggers on five incubating Peruvian pelicans from Isla Lobos de Tierra, Perú, to examine their nocturnality, foraging movements and activities patterns at sea. All instrumented pelicans undertook nocturnal trips during a 5–7 day tracking period. Eighty-seven percent of these trips (n = 13) were strictly nocturnal, whereas the remaining occurred during the day and night. Most birds departed from the island after sunset and returned a few hours after sunrise. Birds traveled south of the island for single-day trips at a maximum range of 82.8 km. Overall, 22% of the tracking period was spent at sea, whereas the remaining time was spent on the island. In the intermediate section of the trip (between inbound and outbound commutes), birds spent 77% of the trip time in floating bouts interspersed by short flying bouts, the former being on average three times longer than the latter. Taken together, the high sinuosity of the bird's tracks during floating bouts, the exclusively nocturnal trips of most individuals, and the fact that all birds returned to the island within a few hours after sunrise suggest that pelicans were actively feeding at night. The nocturnal foraging strategy of Peruvian pelicans may reduce food competition with the sympatric and strictly diurnal Guanay cormorants (Phalacrocorax bougainvillii), Peruvian boobies (Sula variegata) and Blue-footed boobies (S. nebouxii), which were present on the island in large numbers. Likewise, plankton bioluminescence might be used by pelicans as indirect cues to locate anchovies during their upward migration at night. The foraging success of pelicans at night may be enhanced by seizing prey close to the sea surface using a sit-and-wait strategy

Association of kidney disease measures with risk of renal function worsening in patients with type 1 diabetes

Background: Albuminuria has been classically considered a marker of kidney damage progression in diabetic patients and it is routinely assessed to monitor kidney function. However, the role of a mild GFR reduction on the development of stage 653 CKD has been less explored in type 1 diabetes mellitus (T1DM) patients. Aim of the present study was to evaluate the prognostic role of kidney disease measures, namely albuminuria and reduced GFR, on the development of stage 653 CKD in a large cohort of patients affected by T1DM. Methods: A total of 4284 patients affected by T1DM followed-up at 76 diabetes centers participating to the Italian Association of Clinical Diabetologists (Associazione Medici Diabetologi, AMD) initiative constitutes the study population. Urinary albumin excretion (ACR) and estimated GFR (eGFR) were retrieved and analyzed. The incidence of stage 653 CKD (eGFR < 60 mL/min/1.73 m2) or eGFR reduction > 30% from baseline was evaluated. Results: The mean estimated GFR was 98 \ub1 17 mL/min/1.73m2 and the proportion of patients with albuminuria was 15.3% (n = 654) at baseline. About 8% (n = 337) of patients developed one of the two renal endpoints during the 4-year follow-up period. Age, albuminuria (micro or macro) and baseline eGFR < 90 ml/min/m2 were independent risk factors for stage 653 CKD and renal function worsening. When compared to patients with eGFR > 90 ml/min/1.73m2 and normoalbuminuria, those with albuminuria at baseline had a 1.69 greater risk of reaching stage 3 CKD, while patients with mild eGFR reduction (i.e. eGFR between 90 and 60 mL/min/1.73 m2) show a 3.81 greater risk that rose to 8.24 for those patients with albuminuria and mild eGFR reduction at baseline. Conclusions: Albuminuria and eGFR reduction represent independent risk factors for incident stage 653 CKD in T1DM patients. The simultaneous occurrence of reduced eGFR and albuminuria have a synergistic effect on renal function worsening

Perspectives and challenges for the use of radar in biological conservation

Radar is at the forefront for the study of broad-scale aerial movements of birds, bats and insects and related issues in biological conservation. Radar techniques are especially useful for investigating species which fly at high altitudes, in darkness, or which are too small for applying electronic tags. Here, we present an overview of radar applications in biological conservation and highlight its future possibilities. Depending on the type of radar, information can be gathered on local- to continental-scale movements of airborne organisms and their behaviour. Such data can quantify flyway usage, biomass and nutrient transport (bioflow), population sizes, dynamics and distributions, times and dimensions of movements, areas and times of mass emergence and swarming, habitat use and activity ranges. Radar also captures behavioural responses to anthropogenic disturbances, artificial light and man-made structures. Weather surveillance and other long-range radar networks allow spatially broad overviews of important stopover areas, songbird mass roosts and emergences from bat caves. Mobile radars, including repurposed marine radars and commercially dedicated ‘bird radars’, offer the ability to track and monitor the local movements of individuals or groups of flying animals. Harmonic radar techniques have been used for tracking short-range movements of insects and other small animals of conservation interest. However, a major challenge in aeroecology is determining the taxonomic identity of the targets, which often requires ancillary data obtained from other methods. Radar data have become a global source of information on ecosystem structure, composition, services and function and will play an increasing role in the monitoring and conservation of flying animals and threatened habitats worldwide

Functional feasibility in optimal evaluation of water distribution network performances

The traditional approach for the optimization of water distribution networks (WDNs) does not always lead to consistent solutions from an operational point of view. The latest optimization algorithms identify solutions that are “the best solutions” in mathematical terms but that can be less than robust against changes in operating conditions, resulting in the worst case in hydraulically infeasible configurations. Thus, this paper aims to provide a methodology that can synthesize the network performance capabilities under the change in operating conditions with two convergent strategies. The first consists of the implementation of new performance indices (PIs), the demand deficit and the pressure range, and the evaluation of their ability to criticality highlight in operating conditions. The second is the introduction of a new approach to weight the infeasible solutions in the final result, which are those inconsistent with the real hydraulic network performances. The analysis shows that the use of these new indices makes it easier to understand the behavior of the network and to identify any weaknesses. This is true if these indices consider the hydraulically inconsistent solutions that may arise from the simulations of different operation conditions; otherwise, results that poorly represent the real behavior of the network would be obtained

Negli ambiti fluviali: limitazione del rischio idraulico e riequilibrio ambientale e insediativo

Il contributo affronta il tema della gestione integrata delle acque negli ambiti fluviali, proponendosi di superare da un lato il settorialismo di molti interventi recenti, e dall’altro i limiti di strumenti quali i Contratti di fiume, che pur abbracciando una scala intercomunale e promuovendo una visione intersettoriale, hanno inciso marginalmente sulle decisioni assunte. Si propone di formulare dieci progetti-pilota per altrettanti ambiti di bacino italiani, selezionati in base alle criticità ambientali e territoriali emergenti, e qui promuovere interventi idraulici-territoriali integrati entro due principali ambiti d’azione. “A monte”, manutenzione programmata dei versanti e opere di ingegneria verde a basso impatto ambientale, entro un più generale sostegno delle aree interne montane a partire da un ripensamento della politica forestale. “A valle” la massimizzazione degli ambiti di esondazione naturali, la riorganizzazione dell’edificato e del suolo urbanizzato vicino ai corsi d’acqua e un più equilibrato prelievo nei periodi di secca

Laboratory study on the rainfall influence over the sediment transport dynamics on pervious pavements discharge

Infiltration capacity reduction due to the progressive clogging of land surfaces is the most important feature controlling pervious pavement life use. It is influenced by material and local characteristics. The rainfall regime can be influenced by water volume and rainfall intensity. A laboratory study was conducted to analyze the influence of the rainfall intensity on the sediments dynamics on pervious pavements. Three different rainfall intensities were settled using a rainfall simulator: 50 mm/h, 100 mm/h and 150 mm/h. Pervious concrete (PC) and porous asphalt (PA) slabs of 50 × 26 × 5 cm, with void contents of 15%, 20% and 25% were tested. They were clogged using sediments containing mostly sand and an assembled PSD (particle size distribution) that fall within the range of real case scenarios. The sediments were applied over the slabs on aerial loadings of 0.5 kg/m2, 1.0 kg/m2 and 2.0 kg/m2. Using a falling head permeameter discharge measurements were made over the samples in newly built conditions, after clogging and after rainfall simulation. The obtained results showed that in most cases the rainfall intensity does not produce significant differences in discharge time. The information obtained through this study provides better understanding of sediments transport mechanisms on pervious pavements and could lead to customized maintenance routines