9,655 research outputs found
Integrated electronic prescribing and robotic dispensing: a case study
INTRODUCTION: To quantify the benefits of electronic prescribing directly linked to a robotic dispensing machine. CASE DESCRIPTION: Quantitative case study analysis is used on a single case. Hospital A (1,000 beds) has used an integrated electronic prescribing system for 10 years, and in 2009 linked two robotic dispensing machines to the system. The impact on dispensing error rates (quality) and efficiency (costs) were assessed. EVALUATION AND DISCUSSION: The implementation delivered staff efficiencies above expectation. For the out-patient department, this was 16% more than the business case had suggested. For the in-patients dispensary, four staff were released for re-deployment. Additionally, £500,000 in stockholding efficiency above that suggested by the business case was identified. Overall dispensing error rates were not adversely affected and products dispensed by the electronic prescribing - robot system produced zero dispensing errors. The speed of dispensing increased also, as the electronic prescribing - robot combination permitted almost instantaneous dispensing from the point of a doctor entering a prescription. CONCLUSION: It was significant that the combination of electronic prescribing and a robot eliminated dispensing errors. Any errors that did occur were not as a result of the electronic prescribing - robotic system (i.e. the product was not stocked within the robot). The direct linking of electronic prescribing and robots as a dispensing system together produces efficiencies and improves the quality of the dispensing process
An investigation into the behaviour of air rifle pellets in ballistic gel and their interaction with bone
Although air weapons are considerably lower in power than other firearms, there is increasing concern that serious injuries can result from their misuse. The present study was therefore carried out to improve understanding of the terminal ballistic behaviour of air rifle pellets. Pellets were fired into ballistic gel under a variety of conditions. The pellets penetrated further than anticipated from their low cross-sectional density, and Bloom number was not necessarily a good guide to gel behaviour. Pellet penetration into the gel decreased with increasing gel concentration, and appeared to be linear at higher concentrations. Pointed pellets penetrated up to 50% further than rounded pellets. Power and range affect penetration, but other factors are also important, and power alone is not a simple guide to potential penetration. Test firings were also carried out firing pellets into ballistic gel that contained sections of animal bone. Computed tomography (CT) and visual observation were employed to record the interactions. CT scanning showed potential as a tool for examining pellet damage. The bone appeared to be undamaged, but the pellets were severely deformed on impact. If the pellet strikes the bone at an angle, less energy is absorbed by the impact and the pellet fragments may ricochet and cause further damage in the gel. A tentative model is proposed for estimating the energy absorbed by the impact
Treatments for spasticity and pain in multiple sclerosis: a systematic review
Objectives:
To identify the drug treatments currently
available for the management of spasticity and pain in
multiple sclerosis (MS), and to evaluate their clinical and
cost-effectiveness.
Data sources:
Electronic bibliographic databases,
National Research Register, MRC Clinical Trials Register
and the US National Institutes of Health Clinical Trials
Register.
Review methods:
Systematic searches identified 15
interventions for the treatment of spasticity and 15
interventions for treatment of pain. The quality and
outcomes of the studies were evaluated. Reviews of
the treatment of spasticity and pain when due to other
aetiologies were also sought.
Results:
There is limited evidence of the effectiveness
of four oral drugs for spasticity: baclofen, dantrolene,
diazepam and tizanidine. Tizanidine appears to be no
more effective than comparator drugs such as baclofen
and has a slightly different side-effects profile. Despite
claims that it causes less muscle weakness, there was
very little evidence that tizanidine performed any
better in this respect than other drugs, although it is
more expensive. The findings of this review are
consistent with reviews of the same treatments for
spasticity derived from other aetiologies. There is good
evidence that both botulinum toxin (BT) and intrathecal
baclofen are effective in reducing spasticity, and both
are associated with functional benefit. However, they
are invasive, and substantially more expensive. None of
the studies included in the review of pain were
designed specifically to evaluate the alleviation of pain
in patients with MS and there was no consistency
regarding the use of validated outcome measures. It
was suggested that, although expensive, the use of
intrathecal baclofen may be associated with significant
savings in hospitalisation costs in relation to bed-bound
patients who are at risk of developing pressure sores,
thus enhancing its cost-effectiveness. No studies of
cost-effectiveness were identified in the review
of pain. There is evidence, albeit limited, of the
clinical effectiveness of baclofen, dantrolene,
diazepam, tizanidine, intrathecal baclofen and BT
and of the potential cost-effectiveness of intrathecal
baclofen in the treatment of spasticity
in MS.
Conclusions:
Many of the interventions identified are
not licensed for the alleviation of pain or spasticity in
MS and the lack of evidence relating to their
effectiveness may also limit their widespread use.
Indeed, forthcoming information relating to the use of
cannabinoids in MS may result in there being better
evidence of the effectiveness of new treatments than of
any of the currently used drugs. It may therefore be of
value to carry out double-blind randomised controlled
trials of interventions used in current practice, where
outcomes could include functional benefit and impact
on quality of life. Further research into the
development and validation of outcomes measures for
pain and spasticity may also be useful, as perhaps would
cost–utility studies
Subordination in Children’s Writing
This paper reports an investigation into the use of subordinate clauses in the writing of a class of seven to nine year old children when attempting five different writing tasks. The investigation was undertaken in part-response to an inspection report on the school by the Office for Standards in Education (Ofsted) which recommended that the school should extend the writing skills of pupils in this age-range. The importance of developing subordination in writing is related to previous research and to evidence from reviews of Ofsted inspection evidence. The different patterns of subordination are discussed, between tasks and pupils and in relation to variation in the writing of individual children when tackling the different tasks. The paper ends by suggesting how similar informal investigations can assist schools in promoting writing development. It also outlines how the teaching approaches outlined in the National Literacy Strategy will provide opportunities for this promotion, particularly by exploiting links between reading and writing
Study of the 2-d CP(N-1) models at \theta=0 and \pi
We present numerical results for 2-d CP(N-1) models at \theta=0 and \pi
obtained in the D-theory formulation. In this formulation we construct an
efficient cluster algorithm and we show numerical evidence for a first order
transition for CP(N-1\geq 2) models at \theta = \pi. By a finite size scaling
analysis, we also discuss the equivalence in the continuum limit of the
D-theory formulation of the 2-d CP(N-1) models and the usual lattice
definition.Comment: 3 pages, 2 figures. Talk presented at Lattice2004(spin), Fermilab,
June 21-26, 200
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