3,182 research outputs found

    Fastening on the F-14A for cost effective fatigue resistance

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    Cost effectiveness airframe considerations dictated a variable geometry wing design that requires weight optimization, maximum working stress resistance and minimum fatigue concentration factors. The extensive use of titanium structural materials employed electron beam welding methods and interference fit fastening techniques as principle mechanical joining means for economic F-14A production and reliability engineering

    The influence of single base triplet changes on the stability of a Pur·Pur·Pyr triple helix determined by affinity cleaving

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    The influence of sixteen base triplet changes at a single position within a pur·pur·pyr triple helix was examined by affinity cleaving. For the 15 base pair target site studied here, G·GC, A·AT and T·AT triplets stabilize a triple helix to a greater extent than the other 13 natural triplets (pH = 7.4, 25°C). Weaker interactions were detected for the C·AT, A·GC and T·CG triplets. The absence of specific, highly stabilizing interactions between third strand bases and the CG or TA base pairs demonstrates a current sequence limitation to formation of this structure. Models for the two dimensional base triplet interactions for all possible 16 natural triplets are presented

    Effects of Cathode Configuration on Hall Thruster Cluster Plume Properties

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76620/1/AIAA-24636-518.pd

    Plasma Properties in the Plume of a Hall Thruster Cluster

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76225/1/AIAA-3765-486.pd

    Low NO sub x heavy fuel combustor concept program

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    A gas turbine technology program to improve and optimize the staged rich lean low NOx combustor concept is described. Subscale combustor tests to develop the design information for optimization of the fuel preparation, rich burn, quick air quench, and lean burn steps of the combustion process were run. The program provides information for the design of high pressure full scale gas turbine combustors capable of providing environmentally clean combustion of minimally of minimally processed and synthetic fuels. It is concluded that liquid fuel atomization and mixing, rich zone stoichiometry, rich zone liner cooling, rich zone residence time, and quench zone stoichiometry are important considerations in the design and scale up of the rich lean combustor

    Active inference, evidence accumulation, and the urn task

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    Deciding how much evidence to accumulate before making a decision is a problem we and other animals often face, but one that is not completely understood. This issue is particularly important because a tendency to sample less information (often known as reflection impulsivity) is a feature in several psychopathologies, such as psychosis. A formal understanding of information sampling may therefore clarify the computational anatomy of psychopathology. In this theoretical letter, we consider evidence accumulation in terms of active (Bayesian) inference using a generic model of Markov decision processes. Here, agents are equipped with beliefs about their own behavior--in this case, that they will make informed decisions. Normative decision making is then modeled using variational Bayes to minimize surprise about choice outcomes. Under this scheme, different facets of belief updating map naturally onto the functional anatomy of the brain (at least at a heuristic level). Of particular interest is the key role played by the expected precision of beliefs about control, which we have previously suggested may be encoded by dopaminergic neurons in the midbrain. We show that manipulating expected precision strongly affects how much information an agent characteristically samples, and thus provides a possible link between impulsivity and dopaminergic dysfunction. Our study therefore represents a step toward understanding evidence accumulation in terms of neurobiologically plausible Bayesian inference and may cast light on why this process is disordered in psychopathology

    Correspondence from E.B. Lovejoy, August 13, 1862

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    Correspondence from E.B. Lovejoy regarding absent soldiers from Androscoggin Countyhttps://digitalmaine.com/absent_soldiers/1005/thumbnail.jp

    The influence of single base triplet changes on the stability of a Pur·Pur·Pyr triple helix determined by affinity cleaving

    Get PDF
    The influence of sixteen base triplet changes at a single position within a pur·pur·pyr triple helix was examined by affinity cleaving. For the 15 base pair target site studied here, G·GC, A·AT and T·AT triplets stabilize a triple helix to a greater extent than the other 13 natural triplets (pH = 7.4, 25°C). Weaker interactions were detected for the C·AT, A·GC and T·CG triplets. The absence of specific, highly stabilizing interactions between third strand bases and the CG or TA base pairs demonstrates a current sequence limitation to formation of this structure. Models for the two dimensional base triplet interactions for all possible 16 natural triplets are presented
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