2,371 research outputs found

    Caring for America’s aging population: a profile of the direct-care workforce

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    Direct-care workers constitute a low-wage, high-turnover workforce with low levels of health insurance; taking these characteristics into account guides the challenge of how to deal with the growing demand for long-term care by an aging U.S. population

    Investigation of variables in turbine erosion, influence of aerodynamic and geometric parameters

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    Influence of aerodynamic and geometric parameters in turbine erosio

    The Creation of a Next-Generation Cancer Treatment Using Photodynamic Therapy

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    Photodynamic therapy (PDT) is a treatment for various health disorders, including cancer, that uses a photosensitive agent and light. Unlike other cancer treatments, PDT is a focused treatment that kills cancerous cells without harming the surrounding tissues. When a photosensitive agent is administered, it accumulates in the tumor as it binds to low density lipoproteins. When the tumor is exposed to a specific wavelength of light, the photosensitive agent is activated; this results in the release singlet oxygen, which kills the tumor. The objective of this research was to synthesize and characterize a novel photosensitive agent, H2TPP-2A2E. Purification of the novel be used in the next generation of photodynamic therapy. material was achieved using column chromatography. In addition, IR, UV-vis, and NMR spectroscopies were used to characterize the product, and purity was determined using HPLC. After determining that our product was refined, cytotoxicity testing in light and dark conditions revealed that the novel H2TPP-2A2E, could potentially be used in the next generation of photodynamic therapy

    Distinctive versus Common Feature Knowledge across Three Levels of Importance: Relationship with Word Retrieval Performance in People with Aphasia

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    Semantic Feature Analysis (SFA) is a well established intervention technique for improving word retrieval in people with aphasia. This technique uses features of target words to activate semantic networks and thereby improve word retrieval as supported by the spreading activation theory of semantic processing (Collins & Loftus, 1975). Variations of this intervention technique have been successful at improving word retrieval of some people with aphasia (e.g., Boyle, 2004; Coelho, McHugh, & Boyle, 2000; Peach & Reuter, 2010; Wambaugh & Ferguson, 2007). As part of an effort to increase the effectiveness of semantic treatments such as SFA, semantic feature knowledge of people with aphasia has been examined in depth (Cox, 2009; Germani & Pierce 1995; Mason-Baughman, 2009; Mason-Baughman, 2010; Vecchi, 1994). For purposes of this research, feature knowledge refers to the ability to identify that a feature belongs to a particular target word during a sorting task as described below. To develop understanding of the semantic knowledge of people with aphasia, researchers have primarily examined two aspects of features: importance and distinctiveness
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