Improving deep decarbonization modelling capacity for developed and developing country contexts

Energy models are essential for the development of national or regional deep decarbonization pathways (DDPs), providing the necessary analytical framework to systematically explore the system transitions that are required. However, this is challenging due to the long time horizon, the numerous data requirements and the need for transparent, credible approaches that can provide insights into complex transitions. This article explores how this challenge has been met to date, based on a review of the literature and the experiences of practitioners, drawing in particular on the Deep Decarbonization Pathways Project (DDPP), a collaborative effort by 16 national modelling teams. The article finds that there are a range of modelling approaches that have been used across different country contexts, chosen for different reasons, with recognized strengths and weaknesses. The key motivations for use of a given approach include being fit-for-purpose, having in-country capacity and the intertwined goals of transparency, communicability and policy credibility. From the review, a conceptual decision framework for DDP analysis is proposed. This three step process incorporates policy priorities, national characteristics and the model-agnostic principles that drive model choices, considering the needs and capabilities of developed and developing countries, and subject to data and analytical practicalities. Finally an agenda for the further development of modelling approaches is proposed, which is vital for strengthening capacity. These include a focus on model linking, incorporating behaviour and policy impacts, the flexibility to handle distinctive energy systems, incorporating wider environmental constraints and the development of entry-level tools. The latter three are critical for application in developing countries. Policy relevance Following the Paris Agreement, it is essential that modelling approaches are available to enable governments to plan how to decarbonize their economies in the long term. This article takes stock of current practices, identifies the strengths and weaknesses of existing approaches and proposes how capacity can be strengthened. It also provides some practical guidance on the process of choosing modelling approaches, given national priorities and circumstances. This is particularly relevant as countries revisit their Nationally Determined Contributions to meet the global objective of remaining well below a 2°C average global temperature increase

Grit ingestion and size-related consumption of tubers by Graylag Geese

In herbivorous birds the processing rate of food is constrained by gizzard capacity. To enhance digestive processes, many species ingest grit to grind the food. Grit ingestion, however, may further limit the capacity of file gizzard. Graylag Geese (Anser anser) wintering in SW Spain fed mainly on Alkali Bulrush (Scirpus maritimus) tubers, showing a preference for small tubers. This preference may be due to a faster disintegration of small tubers than larger ones inside the gizzard. As larger tubers are likely coarser than smaller tubers, more grit would be necessary to process larger tubers. However, the ingestion of more grit to grind large tubers would be at the expense of ingesting additional tubers because of gizzard capacity limitations. Under these circumstances, there may be an inverse relationship between tuber size and amount of grit ingested to optimize food ingestion. Indeed, we found such a relationship. Grit facilitated the disintegration of tubers. This suggests that relying on some amount of grit to facilitate the grinding of food should outweigh the loss of gizzard capacity to the amount of food ingested.Peer Reviewe

New Technologies’ Promise to the Self and the Becoming of the Sacred: Insights from Georges Bataille’s Concept of Transgression

This article draws on Georges Bataille’s concept of transgression, a key element in Bataille’s theory of the sacred, to highlight structural implications of the way the self-empowerment ethos of new technologies suffuses the digital tracking culture. Pointing to the original conceptual stance of transgression, worked out against prohibition, I first argue that, beyond a critique of new technologies’ promise of self-empowerment as coming at the expense of an acknowledgement of the ultimate taboo—death—is the problem of the sanitizing of the tension between the crossing of the line of the symbolic taboo and prohibition; this undermines a “libidinal investment” towards the sacred, which is central in Bataille’s theory. Second, focussing on “eroticism”, since this embodies the emancipative potential of the Bataillean sacred, I argue that while a fear of eroticism marks out the digital technological realm, this is covered up by the blurring of boundaries between pleasure, fun and sex(iness) that currently governs our experience with technological devices

A humanised anti-IGF-1R monoclonal antibody (AVE1642) enhances Bortezomib-induced apoptosis in myeloma cells lacking CD45

The humanised form of an antagonistic anti-IGF-1R mAb (AVE1642) selectively inhibits the growth of CD45neg myeloma cells. AVE1642 strongly increased bortezomib-induced apoptosis, correlated with an increase of Noxa expression. These results support the therapeutic use of anti-IGF-1R/bortezomib in CD45neg Myeloma patients, particularly those with the most aggressive form, t(4,14)

Population genetics of abnormal haemoglobins in Burkina Faso, West Africa

Les fréquences géniques des hémoglobines A (HbA), HbS et HbC, ont été étudiées au Burkina-Faso (BF) ainsi que dans une région avoisinante du Niger : Ayorou. La fréquence d'HbS est plus élevée dans le Sahel (Nord du BF et Ayorou) que dans la zone de savane. L'inverse est trouvé pour HbC. Les résultats essentiels de ce travail sont : (a) la confirmation d'un pic de la fréquence génique de HbC dans le centre du BF (plateau Mossi); (b) une corrélation négative entre les fréquences de HbS et HbC. Cavalli-Sforza et Bodmer ont observé que cette corrélation atteint une intensité significativement différente de celle qui est attendue, par suite de la relation allélique entre HbS et HbC; (c) la comparaison de ces résultats avec les données rassemblées par Livingstone montre une modification de la valeur sélective des différents génotypes au cours des dernières années. Les individus AS ont une valeur sélective plus basse et les AA et SS en ont une plus haute. Nos données sont favorables à l'hypothèse du relâchement partiel de la sélection dans cette région. (Résumé d'auteur