Analytical computation of the off-axis Effective Area of grazing incidence X-ray mirrors

Focusing mirrors for X-ray telescopes in grazing incidence, introduced in the 70s, are characterized in terms of their performance by their imaging quality and effective area, which in turn determines their sensitivity. Even though the on-axis effective area is assumed in general to characterize the collecting power of an X-ray optic, the telescope capability of imaging extended X-ray sources is also determined by the variation in its effective area with the off-axis angle. [...] The complex task of designing optics for future X-ray telescopes entails detailed computations of both imaging quality and effective area on- and off-axis. Because of their apparent complexity, both aspects have been, so far, treated by using ray-tracing routines aimed at simulating the interaction of X-ray photons with the reflecting surfaces of a given focusing system. Although this approach has been widely exploited and proven to be effective, it would also be attractive to regard the same problem from an analytical viewpoint, to assess an optical design of an X-ray optical module with a simpler calculation than a ray-tracing routine. [...] We have developed useful analytical formulae for the off-axis effective area of a double-reflection mirror in the double cone approximation, requiring only an integration and the standard routines to calculate the X-ray coating reflectivity for a given incidence angle. [...] Algebraic expressions are provided for the mirror geometric area, as a function of the off-axis angle. Finally, the results of the analytical computations presented here are validated by comparison with the corresponding predictions of a ray-tracing code.Comment: 12 pages, 11 figures, accepted for publication in "Astronomy & Astrophysics", section "Instruments, observational techniques, and data processing". Updated version after grammatical revision and typos correctio

Is arrhythmogenic right ventricular cardiomyopathy a paediatric problem too?

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a heart muscle disease that is often familial, characterized by arrhythmias of right ventricular origin, due to transmural fatty or fibrofatty replacement of atrophic myocardium. ARVC is usually diagnosed in the clinical setting between 20 and 40 years of age. The disease is seldom recognised in infancy or under the age of 10, probably because the clinical expression of the disease is normally postponed to youth and adulthood. This review focuses its attention to the pediatric age, defined as the period of life raging from birth to 18 years. During this span of life, ARVC is not so rare as previously supposed and can be identified by applying the same diagnostic criteria proposed for the adult. Ventricular arrhythmias range from isolated ventricular arrhythmias to sustained ventricular tachycardia and fibrillation. Children and adolescents with ARVC must be carefully evaluated and followed-up especially when a family positive history is present, taking into account the high probability during this life-period that asymptomatic affected patients become symptomatic or that arrhythmias worsen during follow-up. The recent identification of the first defective gene opens new avenues for the early identification of affected subjects even when asymptomatic.peer-reviewe

Drell-Yan phenomenology in the color dipole picture revisited

An extensive phenomenological study of the Drell-Yan (DY) process in $pp$ collisions at various energies is performed in the color dipole framework. Besides previously studied $\gamma^*$ production we have also included the $Z^0$ contribution relevant at large dilepton invariant masses. We investigate the DY cross section differential in invariant mass, rapidity and transverse momentum of the dilepton pair in $pp$ collisions at RHIC and LHC. We consider three different phenomenological models for the dipole cross section and found a reasonable agreement with the available data. As a further test of the color dipole formalism, we also study the correlation function in azimuthal angle between the dilepton pair and a forward pion $\Delta\phi$ for different energies, dilepton rapidites and invariant masses. The characteristic double-peak structure of the correlation function around $\Delta \phi\simeq \pi$ found for very forward pions and low-mass dilepton pairs is sensitive to the saturation effects and can be tested by future DY measurements in $pp$ collisions.Comment: 16 pages, 12 figures; typos corrected, references added, conclusions unchange

Joint Attention in the Child with Autism: An Appropriate Play Intervention for Children with Autism Spectrum Disorder

The effects of an Appropriate Play Intervention program, given to three children diagnosed with Autism Spectrum Disorder, were evaluated through a multiple-baseline design across subjects. The research targeted two main skills, appropriate play and joint attention engagement, through the use of an Appropriate Play Intervention program. Children were taught the appropriate use of toys in play behavior with another individual, and measurements collected pre- and post-treatment were used to assess their progress. Upon introduction to the intervention, children showed a rapid increase in their acquisition of appropriate play skills and joint attention engagements, revealing a new perspective from which researchers can approach the deficiencies of joint attention skills in children with low-functioning Autism Spectrum Disorder

Photon and Pomeron -- induced production of Dijets in pppp, pApA and AAAA collisions

In this paper we present a detailed comparison of the dijet production by photon -- photon, photon -- pomeron and pomeron -- pomeron interactions in $pp$, $pA$ and ${\rm AA}$ collisions at the LHC energy. The transverse momentum, pseudo -- rapidity and angular dependencies of the cross sections are calculated at LHC energy using the Forward Physics Monte Carlo (FPMC), which allows to obtain realistic predictions for the dijet production with two leading intact hadrons. We obtain that \gamma \pom channel is dominant at forward rapidities in $pp$ collisions and in the full kinematical range in the nuclear collisions of heavy nuclei. Our results indicate that the analysis of dijet production at the LHC can be useful to test the Resolved Pomeron model as well as to constrain the magnitude of the absorption effects.Comment: 11 pages, 6 figures, 1 table. Improved and enlarged version published in European Physical Journal

Scaling function in AdS/CFT from the O(6) sigma model

Asymptotic behavior of the anomalous dimensions of Wilson operators with high spin and twist is governed in planar N=4 SYM theory by the scaling function which coincides at strong coupling with the energy density of a two-dimensional bosonic O(6) sigma model. We calculate this function by combining the two-loop correction to the energy density for the O(n) model with two-loop correction to the mass gap determined by the all-loop Bethe ansatz in N=4 SYM theory. The result is in agreement with the prediction coming from the thermodynamical limit of the quantum string Bethe ansatz equations, but disagrees with the two-loop stringy corrections to the folded spinning string solution.Comment: 25 pages, 2 figure

Cusp anomalous dimension in maximally supersymmetric Yang-Mills theory at strong coupling

We construct an exact analytical solution to the integral equation which is believed to describe logarithmic growth of the anomalous dimensions of high spin operators in planar N=4 super Yang-Mills theory and use it to determine the strong coupling expansion of the cusp anomalous dimension.Comment: 5 pages. v3: minor corrections, references and important note adde

Longitudinal spin Seebeck coefficient: heat flux vs. temperature difference method

The determination of the longitudinal spin Seebeck effect (LSSE) coefficient is currently plagued by a large uncertainty due to the poor reproducibility of the experimental conditions used in its measurement. In this work we present a detailed analysis of two different methods used for the determination of the LSSE coefficient. We have performed LSSE experiments in different laboratories, by using different setups and employing both the temperature difference method and the heat flux method. We found that the lack of reproducibility can be mainly attributed to the thermal contact resistance between the sample and the thermal baths which generate the temperature gradient. Due to the variation of the thermal resistance, we found that the scaling of the LSSE voltage to the heat flux through the sample rather than to the temperature difference across the sample greatly reduces the uncertainty. The characteristics of a single YIG/Pt LSSE device obtained with two different setups was $(1.143\pm0.007)\cdot 10^{-7}$ Vm/W and $(1.101\pm0.015)\cdot 10^{-7}$ Vm/W with the heat flux method and $(2.313\pm0.017)\cdot 10^{-7}$ V/K and $(4.956\pm0.005)\cdot 10^{-7}$ V/K with the temperature difference method. This shows that systematic errors can be considerably reduced with the heat flux method.Comment: PDFLaTeX, 10 pages, 6 figure

Direct calorimetric measurements of isothermal entropy change on single crystal W-type hexaferrites at the spin reorientation transition

We report on the magnetic field induced isothermal entropy change, \Delta s(Ha, T), of W-type ferrite with CoZn substitution. Entropy measurements are performed by direct calorimetry. Single crystals of the composition BaCo$_0.62$Zn$_1.38$Fe$_16$O$_27$, prepared by the flux method, are measured at different fixed temperatures under an applied field perpendicular and parallel to the c axis. At 296 K one deduces a value of K$_1$ = 8.7 \times 10^{4} J m$^-3$ for the first anisotropy constant, which is in good agreement with the literature. The spin reorientation transition temperature is estimated to take place between 200 and 220 K

J Acquir Immune Defic Syndr

We describe HIV-1 evolutionary dynamics in the 4 participants from the TDF2-PrEP trial who became HIV-1 infected while prescribed emtricitabine and tenofovir disoproxil fumarate (FTC/TDF). At seroconversion, virus diversity in the 2 participants with detectable drug was only 0.05% (95% confidence intervals: 0.04 to 0.06) and 0.07% (0.06 to 0.08) compared with 2.25% (1.95 to 2.6) and 0.42% (0.36 to 0.49) in those with no detectable drug and 0.07%-0.69% in 5 placebo recipients (P > 0.5). At 10 months, diversity in adherent participants was only 0.37% (0.31 to 0.41) and 0.86% (0.82 to 0.90) compared with 0.5%-1.7% among participants who did not take FTC/TDF (P > 0.5). Although limited by the small number of infections that reduced the power to detect differences, we found that sequences from seroconverters with detectable drug were more homogeneous than those from placebo or nonadherent seroconverters.26689970PMC487657