Typology of Innovative Development of AIRR-Regions (Association of Russian Innovative Regions)

The article describes typology of regions of AIRR based on factor and cluster analysis. The main purpose of typology in this study is seeking for opportunities to transform interregional differentiation from problem into an additional source of development of regions with different complementary models of innovation development. It highlights 4 main and 2 additional types (subtypes) of regions of AIRR: Type 1 “Industrial innovation-active regions” (Subtype 1 “regions with developed medium-technological industries” and Subtype 2 “regions with developed high-technological industries”), Type 2 “Industrial regions providing demand for innovations (“market”), Type 3 “Regions with developed scientific-educational complex”, Type 4 “Mixed (catching-up)”. Peculiarities of different types of regions allow each region achieving an efficient innovative activity through complementarity of resources if each region fulfills its role, defined by type of innovative development. It makes actual the problem of development of mechanism of interregional innovation policy as one of the area of development of a synergistic approach in the state innovative policy

Typology of Innovative Development of AIRR-Regions (Association of Russian Innovative Regions)

The article describes typology of regions of AIRR based on factor and cluster analysis. The main purpose of typology in this study is seeking for opportunities to transform interregional differentiation from problem into an additional source of development of regions with different complementary models of innovation development. It highlights 4 main and 2 additional types (subtypes) of regions of AIRR: Type 1 “Industrial innovation-active regions” (Subtype 1 “regions with developed medium-technological industries” and Subtype 2 “regions with developed high-technological industries”), Type 2 “Industrial regions providing demand for innovations (“market”), Type 3 “Regions with developed scientific-educational complex”, Type 4 “Mixed (catching-up)”. Peculiarities of different types of regions allow each region achieving an efficient innovative activity through complementarity of resources if each region fulfills its role, defined by type of innovative development. It makes actual the problem of development of mechanism of interregional innovation policy as one of the area of development of a synergistic approach in the state innovative policy

Economic and Technological Role of Kuzbass Industry in the Implementation of National Energy Strategy of Russian Federation

This article describes the problems and prospects of development of coal mining in Kuzbass - the center of coal production in Siberia and Russia, in the framework of the major initiatives of the National Energy Strategy for the period until 2035. The structural character of the regional coal industry problems, caused by decline in investment activity, high level of fixed assets depreciation, slow development of deep coal processing and technological reduction of coal mining is shown

Innovative Technics of Managing Engineers' Global Competencies

Higher education modernization in the CIS countries takes place under the conditions of dynamic changes in economy and society. These changes are determined by the social and economic development of the country and the world globalization processes - cross-border intercultural communication, knowledge transparency, and the establishment of information society. Educational globalization is a continuous process of creating a unified global educational system, in which the distinctions between its member educational systems are being blended

Comparative assessment of physicians’ and senior medical students’ basic knowledge in treatment of chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is one of the most common pathologies of the respira-tory system. This disease ranks third in the group of the main causes of death in the world. The effective treatment of COPD has been developed by today. However, a significant part of physicians has an insufficient amount of education in this matter

Повышение цифровых навыков: ключ к цифровой вовлеченности пожилых людей (на примере Вьетнама)

Digital transformation taking place rapidly in all aspects of socioeconomic activities across Vietnam in recent years is affecting the lives of people of all ages. Vietnamese older people, due to the impact of digitization, demographic category and socioeconomic status as well as age-related issues, become vulnerable, facing many challenges in adapting to the digital environment. In the article, the existence of a digital divide within Vietnamese older persons at different levels and the disparities in digital skills that have a dominant influence on Internet usage and benefits have been confirmed; low basic digital skills was considered as a barrier to digital inclusion of older adults in the emerging digital society. The aim of the study is to predict the socio-economic consequences and find practical solutions to improve the literacy and disease skills of people in Vietnam, including the formation of an effective form of digital literacy and digital skills training. The article proposes measures to bridge the sudden gap in human diseases and encourage their adaptation to the emerging digital societyЦифровая трансформация, быстро происходящая во всех аспектах социально-экономической деятельности во Вьетнаме в последние годы, влияет на жизнь людей всех возрастов. Пожилые вьетнамцы под влиянием цифровизации, объективных демографических и социально-экономических процессов, а также проблем, связанных с возрастом, становятся уязвимыми, сталкиваясь со многими проблемами при адаптации к цифровой среде. В статье подтверждается наличие цифрового неравенства среди пожилых вьетнамцев на разных уровнях овладения цифровыми навыками, которые оказывают доминирующее влияние на использование преимуществ сети Интернет. В ходе исследования установлено, что низкие базовые цифровые навыки послужили препятствием для интеграции пожилых людей в развивающееся цифровое общество. Цель исследования заключается в прогнозировании социально-экономических последствий и поиске практических решений по повышению цифровой грамотности и навыков пожилых людей Вьетнама, включая становление эффективных форм распространения цифровой грамотности и обучения цифровым навыкам. В статье предложены меры по преодолению цифрового разрыва среди пожилых людей и поощрению их адаптации к формирующемуся цифровому обществ

Assessment of physicians’ and senior medical students’ knowledge in treatment of patients with community-acquired pneumonia: Current results of the KNOCAP project

Community-acquired pneumonia (CAP) remains one of the most acute problems of bronchopulmonary pathology being the 4th in the mortality structure (after cardiovascular, cerebrovascular diseases and malignant neoplasms) and the 1st among all fatalities from infectious diseases. Thanks to the scientific progress achieved in the antibiotic therapy and vaccine prophylaxis, the death toll has decreased four times compared to its rate during the “pre-antibiotic era“. However, nowadays there is a steadily increasing trend in the pneumonia mortality rate in Russia. The only possible way to increase efficacy of CAP treatment is timely initiated rational antibiotic therapy, considering the possible etiologies, risk factors and the severity of the patient’s condition

Canagliflozin and renal outcomes in type 2 diabetes and nephropathy

BACKGROUND Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium–glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes. METHODS In this double-blind, randomized trial, we assigned patients with type 2 diabetes and albuminuric chronic kidney disease to receive canagliflozin, an oral SGLT2 inhibitor, at a dose of 100 mg daily or placebo. All the patients had an estimated glomerular filtration rate (GFR) of 30 to <90 ml per minute per 1.73 m2 of body-surface area and albuminuria (ratio of albumin [mg] to creatinine [g], >300 to 5000) and were treated with renin–angiotensin system blockade. The primary outcome was a composite of end-stage kidney disease (dialysis, transplantation, or a sustained estimated GFR of <15 ml per minute per 1.73 m2), a doubling of the serum creatinine level, or death from renal or cardiovascular causes. Prespecified secondary outcomes were tested hierarchically. RESULTS The trial was stopped early after a planned interim analysis on the recommendation of the data and safety monitoring committee. At that time, 4401 patients had undergone randomization, with a median follow-up of 2.62 years. The relative risk of the primary outcome was 30% lower in the canagliflozin group than in the placebo group, with event rates of 43.2 and 61.2 per 1000 patient-years, respectively (hazard ratio, 0.70; 95% confidence interval [CI], 0.59 to 0.82; P=0.00001). The relative risk of the renal-specific composite of end-stage kidney disease, a doubling of the creatinine level, or death from renal causes was lower by 34% (hazard ratio, 0.66; 95% CI, 0.53 to 0.81; P<0.001), and the relative risk of end-stage kidney disease was lower by 32% (hazard ratio, 0.68; 95% CI, 0.54 to 0.86; P=0.002). The canagliflozin group also had a lower risk of cardiovascular death, myocardial infarction, or stroke (hazard ratio, 0.80; 95% CI, 0.67 to 0.95; P=0.01) and hospitalization for heart failure (hazard ratio, 0.61; 95% CI, 0.47 to 0.80; P<0.001). There were no significant differences in rates of amputation or fracture. CONCLUSIONS In patients with type 2 diabetes and kidney disease, the risk of kidney failure and cardiovascular events was lower in the canagliflozin group than in the placebo group at a median follow-up of 2.62 years

Quality of life of an elderly person in the conditions of urban space

The article considers the problem of the quality of life of the elderly in the city. A high-quality innovative urban environment is understood as a safe, comfortable space for living and recreation using smart city (home) technologies, adapted for all social groups of the population, including age groups. In modern Russia, the demographic situation requires paying attention to the compliance with city standards and criteria for the quality of life of seniors in a digital economy. This work is relevant today due to the increase in the retirement age. Principles of the active ageing effective strategy shall be based on the social partnership of state and elderly people. In the context of the foregoing, the quality of life of an elderly person is becoming increasingly important for the formation of a humanistic social urban environment in connection with the need to adapt a person to living conditions that change late in life

Structure of professional knowledge in interstadial transition

The relevance of work is determined by the need for a detailed analysis of the crucial role of knowledge in industrial and post-industrial society through the prism of the «axis principle» of social dynamics and construction of public structures. The main aim of the study: to prove the necessity of determining knowledge parameters in industrial and post-industrial environment, to identify their internal consistency based on network principles; to show the relation between the multiplicity of social development vectors and to identify the underlying causes of the crisis in professional education system.Methods: The authors have applied the approach to society as a system of self-knowledge. Concrete historical specificity and forms of self-sustaining systems of knowledge to industrial society on the basis of the dialectic of living and embodied knowledge are shown. Results: The paper shows the way of encoding the process of structure formation by embodied knowledge dominance in the social scale; what «structural» institutions appear in this process and, the way of programming social dynamics in the generated structures. The authors identified the features of rational knowledge in industrialized world and specific nature of a progress linear model based on dominance of the embodied knowledge. The transition to the dominant role of living knowledge as a social substance determines multiple (alternative) character of the generated (constructible) social reality, social role spectrum of its participants. The structure of social and creative knowledge is changing. Social-role knowledge of the subjects of reality generated plays growing role in this knowledge. The authors make conclusions on congruence of social and creative activity based on knowledge, and the system of forming knowledge ofparticipants of this activit